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Filtered Search Results
Selleck Chemical LLC APTO-253
APTO-253 (LOR-253 LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21) promotes G0-G1 cell-cycle arrest and triggers apoptosis in acute myeloid leukemia (AML) cells APTO-253 is also an inducer of KLF4 (Kr ppel-like factor 4)
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Rieke Metals LLC 3,4-DIFLUOROPHENYL ZN BR
3,4-Difluorophenylzinc bromide, 0.5M THF, 50mL
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Medchemexpress LLC HY-15185 10mg Medchemexpress, Nirogacestat CAS:1290543-63-3 Purity:>98%
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Medchemexpress, HY-15185 10mg Nirogacestat CAS:1290543-63-3 Nirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Rac-zevaquenabant | 1610420-28-4 | 99.2% | 547.98 | C25H21ClF3N5O2S | 5 MG
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(Rac)-Zevaquenabant is a research small molecule described as a cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS) antagonist with reported CB1R Ki ~5.7 nM. It is used in preclinical studies, including liver fibrosis research, and is supplied as a solid or as a ready-to-use solution in DMSO.
- Potent CB1R antagonist with reported Ki of 5.7 nM.
- Also antagonizes inducible nitric oxide synthase (iNOS), useful for dual-pathway studies.
- High purity: 99.2%.
- Available as solid and as a 10 mM solution in DMSO.
- Molecular weight 547.98; formula C25H21ClF3N5O2S.
- Powder storage: -20°C (up to 3 years) or 4°C (up to 2 years); in solvent: -80°C (up to 6 months).
- For research use only; not for human or clinical use.
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eMolecules 1386874-06-1 | Medchem Express | Samotolisib | 5mg | 446261431 | HY-12513 | MFCD28411368 | 406.486 | C23H26N4O3
Medchem Express | Caspofungin (diacetate) | 5mg | 446268114 | HY-17006 | 179463-17-3 | 1213.435 | C56H96N10O19
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eMolecules 1893-33-0 | Medchem Express | Pipamperone | 5mg | 475641434 | HY-100703 | MFCD00242979 | 375.488 | C21H30FN3O2
AstaTech | 111-TRIFLUORO-5-METHYLHEXANE-24-DIONE | 1g | 441563845 | 78793 | 95.000 | 30984-28-2 | MFCD00045106 | 182.142 | C7H9F3O2
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Medchemexpress LLC HY-112654 10mg Medchemexpress, GCN2iB CAS:2183470-12-2 Purity:>98%
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Medchemexpress, HY-112654 10mg GCN2iB CAS:2183470-12-2 GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 85068-28-6 | 2,6-Difluorophenylacetic acid | Ambeed | MFCD00010001 | 172.131 | C8H6F2O2 | 97.000 | OC(=O)Cc1c(F)cccc1F | 1g | 591797928
2,6-Difluorophenylacetic acid | Ambeed | 85068-28-6 | MFCD00010001 | 172.131 | C8H6F2O2 | 97.000 | OC(=O)Cc1c(F)cccc1F | 1g | 591797928
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Medchemexpress LLC PRX-07034 hydrochloride | 903580-39-2 | 98.97% | C21H29Cl2N3O4S | 100 MG
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PRX-07034 hydrochloride is a potent and highly selective 5-HT6 receptor antagonist, exhibiting a Ki of 4-8 nM and an IC50 of 19 nM. This compound is valuable for research focused on enhancing working memory and cognitive flexibility.
- Highly selective 5-HT6 receptor antagonist.
- Demonstrates Ki of 4-8 nM and IC50 of 19 nM for 5-HT6 receptor.
- Supports research in enhancing working memory and cognitive flexibility.
- Shows ≥100-fold selectivity for 5-HT6 receptor over 68 other GPCRs, ion channels, and transporters.
- Inhibits multiple 5-HT and dopamine receptors at varying concentrations.
- Enhances delayed spontaneous alternation and strategy switching in animal models.
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Medchemexpress LLC HY-111271 10mg Medchemexpress, L 888607 CAS:860033-06-3 Purity:>98%
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Medchemexpress, HY-111271 10mg L 888607 CAS:860033-06-3 L 888607 is a potent, and selective CRTH2 (also known as DP2) agonist with a Ki of 0.8 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 845829-91-6 | (R)-1-(4-bromo-2-fluorophenyl)ethan-1-aminehydrochloride | MFCD19105430 | 1g
WuXi ChemSupply | (R)-1-(4-bromo-2-fluorophenyl)ethan-1-aminehydrochloride | 1g | 599169932 | LN02185216 | 95.000 | 845829-91-6 | MFCD19105430 | 254.530 | C8H10BrClFN
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Chemscene ChemScene | (3-Bromo-2-fluorophenyl)boronic acid | 10G | CS-W014779 | 0.98 | 352535-97-8| MFCD05664228 | 218.82
ChemScene | (3-Bromo-2-fluorophenyl)boronic acid | 10G | CS-W014779 | 0.98 | 352535-97-8| MFCD05664228 | 218.82
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Accela Chembio Inc 2 | 4 | 5-trifluorophenylacetic Acid | 100g | 209995-38-0 | MFCD00082479 | 97+% | Shelf Life: 2160 Days | Regular
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2 | 4 | 5-trifluorophenylacetic Acid | 100g | 209995-38-0 | MFCD00082479 | 97+% | Shelf Life: 2160 Days | Regular
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Selleck Chemical LLC GSK583
GSK583 is a highly potent and selective inhibitor of RIP2 kinase with IC50 of 5 nM GSK583 also inhibits both TNF- and IL-6 production with IC50 of 200 nM in explant cultures
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Selleck Chemical LLC Eliprodil
Eliprodil (SL-820715) is a non-competitive NR2B-selective NMDA antagonist with IC50 value of 1 M and is less potent for NR2A- and NR2C-containing receptors with IC50 100 M
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