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Filtered Search Results
eMolecules 220551-92-8 | Medchem Express | DAA-1106 | 5mg | 446270571 | HY-19945 | MFCD17014668 | 395.43 | C23H22FNO4
Ambeed | 3-Chloro-5-fluoroaniline | 5g | 552719184 | A373276 | 4863-91-6 | MFCD03407962 | 145.560 | C6H5ClFN
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eMolecules 1310455-86-7 | 2-(4-FLUOROPHENYL)-8,8-DIMETHYL-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRAZINE | MFCD22690265 | 0.25g
AstaTech | 3-NITROPYRIDINE-4-CARBOXALDEHYDE | 0.25g | 273171906 | 75891 | 95.000 | 153813-70-8 | MFCD06253937 | 152.109 | C6H4N2O3
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Medchemexpress LLC Egfr-in-1 Tfa | 2753348-63-7 | 99.4% | 628.60 | 5 MG
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EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. It potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. It exhibits strong antiproliferative activity against H1975 cells and the first-line mutant HCC827 cells, demonstrating antitumor activity.
- Potently inhibits Gefitinib-resistant EGFR L858R, T790M
- 100-fold selectivity over wild-type EGFR
- Strong antiproliferative activity against H1975 cells and HCC827 cells
- Antitumor activity demonstrated in vivo
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Medchemexpress LLC HY-10992 100mg , AZD-7762 CAS:860352-01-8 Purity:98%
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Medchemexpress, HY-10992 100mg AZD-7762 CAS:860352-01-8 Formula:C17H19FN4O2S IC50: 5 nM (ChK1), 5 nM (ChK2) Purity:98% AZD-7762 is a potent ATP-competitive checkpoint kinase ( Chk ) inhibitor in with IC 50 of 5 nM for Chk1. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC MK-5108 S2770-50mg
MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0 064 nM in a cell-free assay and is 220- and 190-fold more selective for Aurora A than Aurora B/C while it inhibits TrkA with less than 100-fold selectivity MK-5108 (VX-689) induces autophagy Phase 1
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eMolecules 1809403-04-0 | 1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucose | Toronto Research Chemicals460.520 | C24H25FO6SCc1ccc(cc1Cc1ccc(s1)-c1ccc(F)cc1)C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO | 500mg | 601596199
1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucose | Toronto Research Chemicals | 1809403-04-0460.520 | C24H25FO6SCc1ccc(cc1Cc1ccc(s1)-c1ccc(F)cc1)C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO | 500mg | 601596199
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Medchemexpress LLC HY-13058B 5mg Medchemexpress, (R)-ADX-47273 CAS:851881-59-9 Purity:>98%
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Medchemexpress, HY-13058B 5mg (R)-ADX-47273 CAS:851881-59-9 (R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC 50 of 168 nM for potentiation . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Abemaciclib metabolite M18 hydrochloride | 2704316-82-3 | 98.2% | 100 MG
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Abemaciclib metabolite M18 hydrochloride (LSN3106729) is a metabolite of Abemaciclib with antitumor activity, acting as a CDK inhibitor. It has been utilized in the design of PROTAC CDK4/6 degraders.
- Targets cyclin-dependent kinases (CDK4 and CDK6)
- Exhibits antitumor activity
- Soluble in DMSO up to 125 mg/mL for in vitro studies
- Soluble in H2O up to 100 mg/mL for in vitro studies
- Soluble in PBS up to 50 mg/mL for in vivo applications
- Appears as an off-white to light yellow solid
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eMolecules 109008-28-8 | Medchem Express | Mauritianin | 5mg | 495803313 | HY-N5038 | 740.664 | C33H40O19
ChemScene | 1-Bromo-4-chloro-2-ethylbenzene | 100mg | 714104594 | CS-0202561 | 1160573-89-6 | MFCD11846044 | 219.510 | C8H8BrCl
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Medchemexpress LLC RORγt inverse agonist 13 | 2170477-75-3 | 98.1% | 513.29 | C23H17Cl2F3N2O4 | 5 MG
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RORγt inverse agonist 13 (Compound 3i) is a potent, orally active, and selective inverse agonist of the RORγt nuclear receptor with a reported IC50 of 63.8 nM. The compound is supplied for research use and is available as solid and solution formulations with high analytical purity.
- Potent inverse agonist of RORγt with IC50 of 63.8 nM.
- Orally active and selective for RORγt.
- High purity (98.1%) suitable for research applications.
- Molecular weight 513.29; formula C23H17Cl2F3N2O4.
- Available as solid (5-500 mg) and as DMSO solutions for convenient dosing.
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Medchemexpress LLC TMP780 | 1422053-03-9 | 99.5% | 494.58 g/mol | C31H30N2O4 | 100 MG
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TMP780 is a small-molecule inverse agonist of the nuclear receptor RORγt used as a research compound for inflammation and immunology studies. It is reported to have potent biochemical activity and is supplied with high purity for preclinical laboratory use.
- Inverse agonist of RORγt (IC50 13 nM).
- High reported purity (99.51%).
- Molecular formula C31H30N2O4; molecular weight 494.58 g/mol.
- Typically supplied as a solid powder; soluble in DMSO.
- Available in multiple pack sizes, including 100 mg.
- Intended for research use only; not for human or veterinary use.
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Medchemexpress LLC N1,N3,N5-tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide | 2922283-38-1 | 1385.4 g/mol | C93H177N3O3 | 5 MG
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N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an ionizable lipid-like analogue intended for research use in nucleic acid delivery. It is primarily used in formulation and lipid nanoparticle (LNP) studies to evaluate delivery of mRNA, siRNA, and CRISPR/Cas components in preclinical research settings.
- Ionizable lipid-like structure suitable for mRNA and nucleic acid delivery.
- Designed for incorporation into lipid nanoparticle formulations.
- Intended for laboratory research and formulation development.
- Off-white to pale oil appearance, facilitating handling in solution.
- Stable under recommended storage: pure form -20°C (3 years), 4°C (2 years); in solvent -80°C (6 months), -20°C (1 month).
- Not classified as a hazardous substance or mixture per supplier safety data.
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Medchemexpress LLC HY-19733 5mg Medchemexpress, Lumateperone (tosylate) CAS:1187020-80-9 Purity:>98%
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Medchemexpress, HY-19733 5mg Lumateperone (tosylate) CAS:1187020-80-9 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC NAZ2329 | 2809469-05-2 | 99.0% | 501.56 | C21H18F3NO4S3 | 10 MG
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NAZ2329 is a cell-permeable small-molecule inhibitor of receptor-type protein tyrosine phosphatases PTPRZ and PTPRG supplied for research applications. It is characterized by micromolar inhibitory activity and is provided as a solid with recommended formulations for in vivo use.
- CAS number 2809469-05-2; molecular formula C21H18F3NO4S3; molecular weight 501.56.
- Purity 99.02% as supplied.
- Targets PTPRZ (IC50 = 7.5 μM) and PTPRG (IC50 = 4.8 μM); shows activity against other PTP family members.
- Solubility: DMSO 100 mg/mL; in vivo formulation examples and protocols available.
- Storage: powder -20°C (up to 3 years); in solvent -80°C (up to 6 months).
- For research use only; not for clinical use or sale to patients.
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Medchemexpress LLC HY-107486 10mg Medchemexpress, Nosiheptide CAS:56377-79-8 Purity:>98%
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Medchemexpress, HY-107486 10mg Nosiheptide CAS:56377-79-8 Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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