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Filtered Search Results
eMolecules 176182-06-2 | Medchem Express | Depressine | 5mg | 705861638 | HY-N5070 | 688.632 | C30H40O18
Ambeed | (R)-4-Benzyl-2-(quinolin-8-yl)-45-dihydrooxazole | 100mg | 633660596 | A1371343 | 259105-55-0 | 288.350 | C19H16N2O
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Matrix Scientific 1,2-Diamino-4-fluorobenzene, 367-31-7, MFCD00042228, 5g
Molecular Formula C6H7FN2, Purity 98%, Molecular Weight 126.13, Melting Point 86-88°
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Selleck Chemical LLC MAC-545496
MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd 0 1 nM) MAC-545496 can reverse -lactam resistance in methicillin-resistant strains and synergize with CAMPs MAC-545496 shows remarkable activity in macrophages and attenuates S aureus virulence in a G mellonella larvae infection model
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Selleck Chemical LLC Pimitespib TAS-116-5mg
Pimitespib (TAS-116) is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L).
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Medchemexpress LLC HY-103107 5mg Medchemexpress, LY334370 CAS:182563-08-2 Purity:>98%
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Medchemexpress, HY-103107 5mg LY334370 CAS:182563-08-2 LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-111760 10mg Medchemexpress, NRX-252262 CAS: Purity:>98%
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Medchemexpress, HY-111760 10mg NRX-252262 CAS: NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC ELR-510444 S3725-5mg
ELR-510444 is a novel microtubule disruptor with potential antivascular effects and in vivo antitumor efficacy causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells
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Medchemexpress LLC Aurora kinase inhibitor II | 331770-21-9 | 99.1% | 400.43 g·mol⁻1 | C23H20N4O3 | 5 MG
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Aurora kinase inhibitor-2 is a selective, ATP-competitive small-molecule inhibitor of Aurora kinases A and B used in biochemical and cell-based research. It shows inhibitory activity in the low hundreds of nanomolar range and is supplied as a solid suitable for in vitro and in vivo formulation studies.
- Selective ATP-competitive inhibitor of Aurora A and Aurora B (IC50: Aurora A 310 nM; Aurora B 240 nM).
- Supplied as a white to yellow solid with high reported purity (~99.1%).
- Molecular formula C23H20N4O3 and molecular weight 400.43 g·mol⁻1.
- Dissolves readily in DMSO; recommended in vitro solubility 100 mg/mL (ultrasonic may be required).
- Formulatable for in vivo studies using common vehicles (SBE-β-CD, corn oil, PEG300/Tween-80 mixes).
- Intended for research applications probing Aurora kinase function and signaling.
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Medchemexpress LLC HY-15727A 5mg Medchemexpress, Afuresertib (hydrochloride) CAS:1047645-82-8 Purity:>98%
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Medchemexpress, HY-15727A 5mg Afuresertib (hydrochloride) CAS:1047645-82-8 Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Wnt agonist 1(Synonyms: Wnt Agonist I, Wnt signaling activator I, Wnt agonist compound 1, Wnt agonist-I), 10mg, CAS: 853220-52-7.
Wnt agonist 1 (CAS 853220-52-7) is a small-molecule stimulator of the canonical Wnt signaling pathway It functions by activating -catenin-dependent transcription mediated through the TCF transcription factor with an EC50 of approximately 0 7 M In Xenopus embryos treated from developmental stage 10 5 to stage 40 with Wnt agonist 1 (10 M) notable cephalic defects including reduced head size or absent eyes were observed mirroring phenotypes associated with increased Wnt signaling Researchers use Wnt agonist 1 to investigate Wnt pathway-regulated cellular differentiation and development
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Apexbio Technology LLC S/GSK1349572 1051375-16-6 5mg
S GSK1349572 (1051375-16-6) is a small-molecule inhibitor targeting HIV-1 integrase It is designed to inhibit the DNA strand transfer process interfering with viral replication by preventing the integration of viral genomic DNA into host cellular DNA S GSK1349572 exerts its biological activity primarily by binding to the integrase active site and occupying the integrase DNA interface thereby blocking DNA integration In in vitro studies using peripheral blood mononuclear cells S GSK1349572 demonstrates potent anti-HIV activity with an IC50 value of approximately 0 51 nM Based on these pharmacological properties S GSK1349572 holds research potential in antiretroviral resistance studies and HIV drug development
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Apexbio Technology LLC Iloperidone 133454-47-4 10mg
Iloperidone (CAS 133454-47-4) is a small molecule antagonist of dopamine D2 and serotonin 5-HT2 receptors By inhibiting dopaminergic and serotonergic neurotransmission iloperidone modulates pathways implicated in psychotic disorders This compound is utilized in research to investigate receptor pharmacology and the underlying mechanisms of antipsychotic activity Its dual antagonism profile makes it relevant for studies examining the interplay between dopamine and serotonin signaling in neuropsychiatric disease models
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Aobchem 1-Ethyl-3 5-difluorobenzene | ≥95% | CAS 117358-52-8 | C8H8F2 | 25g
1-Ethyl-3 5-difluorobenzene | ≥95% | CAS 117358-52-8 | C8H8F2 | 25g
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Medchemexpress LLC HY-16915 5mg Medchemexpress, RPR-260243 CAS:668463-35-2 Purity:>98%
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Medchemexpress, HY-16915 5mg RPR-260243 CAS:668463-35-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Aobchem Tert-butyl 3-bromo-5-fluorobenzoate | ≥97% | CAS 1262834-57-0 | C11H12BrFO2 | 1g
Tert-butyl 3-bromo-5-fluorobenzoate | ≥97% | CAS 1262834-57-0 | C11H12BrFO2 | 1g
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