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Filtered Search Results
Medchemexpress LLC STING Agonist-12 | 2259624-71-8 | 98.3% | 490.88 | 50 MG
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STING agonist-12 is a potent, orally active human STING activator with an EC50 of 185 nM. It demonstrates excellent pan-polymorph activity across STING proteins in HEK293T cells. This compound is well-absorbed in animal models, exhibiting a short terminal half-life. For research use only.
- Potent, orally active human STING activator
- EC50 of 185 nM against STING
- Excellent pan-polymorph activity
- Not active at mouse STING
- Well-absorbed in animal models
- Short terminal half-life
- Appearance: Solid, light yellow to yellow
- Shipping: Room temperature (continental US)
- Storage: 4°C, protect from light (solid)
- Storage in solvent: -80°C for 6 months; -20°C for 1 month (protect from light)
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eMolecules 494191-73-0 | Medchem Express | GPR35 agonist 2 | 5mg | 778475858 | HY-15705 | MFCD11604018 | 342.34 | C17H11FN2O3S
Medchem Express | NGR peptide (Trifluoroacetate) | 5mg | 446275986 | HY-P1043A | | 722.710 | C22H37F3N10O10S2
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eMolecules 1951408-58-4 | Medchem Express | MAK683 | 5mg | 446258308 | HY-103663 | 376.395 | C20H17FN6O
Ambeed | 24-Dichloro-5-methylbenzonitrile | 100mg | 599356365 | A393431 | 33373-88-5 | MFCD16817654 | 186.040 | C8H5Cl2N
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Accela Chembio Inc 4-bromo-2-fluorophenylacetic Acid | 1g | 114897-92-6 | MFCD09032952 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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4-bromo-2-fluorophenylacetic Acid | 1g | 114897-92-6 | MFCD09032952 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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eMolecules 334792-76-6 | Ethyl 3-bromo-2-fluorobenzoate | MFCD10566819 | 1g
Ambeed | (R)-tert-Butyl (1-oxopropan-2-yl)carbamate | 250mg | 525068467 | A155075 | 82353-56-8 | MFCD00274183 | 173.212 | C8H15NO3
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eMolecules 579-49-7 | 4-Fluorophenyl 2-thienyl ketone | Combi-Blocks | MFCD00044554 | 206.230 | C11H7FOS | 97.000 | Fc1ccc(cc1)C(=O)c1cccs1 | 25g | 448009759
4-Fluorophenyl 2-thienyl ketone | Combi-Blocks | 579-49-7 | MFCD00044554 | 206.230 | C11H7FOS | 97.000 | Fc1ccc(cc1)C(=O)c1cccs1 | 25g | 448009759
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Apexbio Technology LLC Escitalopram Oxalate 219861-08-2 50mg
Escitalopram Oxalate (CAS 219861-08-2) is the S-( )-enantiomer of citalopram and functions as a selective serotonin reuptake inhibitor (SSRI) It exhibits high affinity for the human serotonin transporter (5-HTT) inhibiting [3H]-5-HT uptake with a Ki of 6 6 nM in COS-1 cells expressing 5-HTT and displacing [125I]-RTI-55 with a Ki of 3 9 nM In rat brain synaptosomes Escitalopram Oxalate blocks the accumulation of [3H]-serotonin (IC50 2 1 nM) with markedly lower activity against norepinephrine and dopamine uptake It also shows in vitro affinity for rat histamine H1 receptors and 1 sites Escitalopram Oxalate is widely utilized in neuropharmacological research related to depression and anxiety mechanisms
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Medchemexpress LLC HY-16297A 100mg Medchemexpress, LY2835219 (free base) Abemaciclib;CDK4/6 dual inhibitor CAS:1231929-97-7 Purity:98%
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Medchemexpress,HY-16297A 100mg LY2835219 (free base) Abemaciclib;CDK4/6 dual inhibitor CAS:1231929-97-7 Formula:C27H32F2N8 LY2835219 free base is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Strem, An Ascensus Company CAS# 462-06-6. 25g. Fluorobenzene, 99%. MFCD00000280
CAS# 462-06-6. 25g. Fluorobenzene, 99%. MFCD00000280. Molecular Weight: 96.10. Molecular Formula: C6H5F. Color/form: colorless liq. Strem# 09-3480. http://www.strem.com/catalog/v/09-3480/
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Medchemexpress LLC 5-BDBD | 768404-03-1 | MFCD18086878 | 99.9% | 355.19 | C17H11BrN2O2 | 50 MG
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5-BDBD is a selective small-molecule antagonist of the P2X4 receptor used as a research tool in pharmacology and neuroscience. It inhibits P2X4-mediated currents (reported IC50 ≈0.75 μM) and has demonstrated efficacy in electrophysiology and animal pain models when formulated appropriately.
- Selective P2X4 receptor antagonist for receptor pharmacology studies.
- Demonstrated activity in electrophysiology and in vivo pain models.
- High chemical purity (≈99.9%).
- Available as solid and as 10 mM solution in DMSO for convenience.
- Soluble in DMSO; in vivo formulation protocols available.
- Suitable for in vitro assays and in vivo studies with proper formulation.
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Medchemexpress LLC PT-2385 | 1672665-49-4 | 100.0% | 100 MG
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PT-2385 is a highly selective HIF-2α inhibitor, demonstrating a Ki of less than 50 nM. It acts as an antagonist specifically targeting HIF-2 over HIF-1, with no activity against HIF-1α. In preclinical studies, PT-2385 has shown significant in vivo activity by inhibiting the expression of HIF-2α regulated genes in a dose-dependent manner. This compound has also been observed to induce rapid, dose-dependent tumor regression in models using 786-O and A498 RCC cell lines, typically when administered at 30 or 100 mg/kg via oral gavage twice daily. Additionally, it contributes to reducing tumor-derived VEGFA protein levels, which in turn diminishes proliferation (Ki67) and angiogenesis (CD-31).
- Selective HIF-2α inhibitor
- Inactive against HIF-1α
- Inhibits HIF-2α regulated gene expression
- Induces tumor regression in preclinical models
- Reduces tumor proliferation and angiogenesis
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Apexbio Technology LLC Firategrast 402567-16-2 5mg
Firategrast (CAS 402567-16-2) is a small-molecule antagonist targeting integrins 4 1 and 4 7 It is designed to block integrin-ligand interactions thereby modulating leukocyte trafficking across the vascular endothelium into tissues Firategrast exerts its biological activity primarily through inhibition of leukocyte adhesion and migration particularly suppressing cell entry into the central nervous system (CNS) Based on these pharmacological properties Firategrast holds research potential in the treatment of relapsing-remitting multiple sclerosis (MS) by reducing CNS inflammation via inhibition of leukocyte infiltration
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Medchemexpress LLC HY-113970A 5mg Medchemexpress, Nebracetam (hydrochloride) CAS:1177279-49-0 Purity:>98%
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Medchemexpress, HY-113970A 5mg Nebracetam (HCl) CAS:1177279-49-0 Nebracetam hydrochloride, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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STA Pharmaceutical Fmoc-(R)-3-Amino-4-(pentafluoro-phenyl)-butyric acid | 100 g | CAS 269398-94-9 | MDL MFCD01860941
Fmoc-(R)-3-Amino-4-(pentafluoro-phenyl)-butyric acid is a Amino Acid reagent (Subcategory: Beta AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 269398-94-9
- MDL: MFCD01860941
- InChIKey: HCBMYXPXBOUBBR-GFCCVEGCSA-N
- Molecular Weight: 491.414
- Molecular Formula: C25H18F5NO4
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(perfluorophenyl)butanoic acid
- SMILES: FC1=C(C(F)=C(C(F)=C1C[C@@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)CC(O)=O)F)F
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eMolecules 1616359-00-2 | Medchem Express | SEL24-B489 | 5mg | 719835767 | HY-120758 | 446.143 | C15H18Br2N4O2
Medchem Express | AZD3229 Tosylate | 5mg | 441681894 | HY-112802A | 2248003-71-4 | 651.710 | C31H34FN7O6S
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