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Filtered Search Results
Medchemexpress LLC Fantofarone | 114432-13-2 | MFCD00867144 | 99.9% | 550.71 g·mol⁻¹ | C31H38N2O5S | 25 MG
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Fantofarone is a potent L-type calcium channel antagonist used as a research reagent to investigate calcium channel pharmacology and related cardiovascular signaling pathways. It is a sulfone-indolizine class compound with molecular formula C31H38N2O5S and a molecular weight of 550.71 g·mol⁻¹. The material is supplied for research use only and is not intended for human or veterinary use.
- Potent L-type calcium channel antagonist for in vitro pharmacology.
- High reported purity suitable for analytical characterization.
- Solid reagent convenient for formulation and dosing in laboratory assays.
- Supplied in small research quantities appropriate for experimental workflows.
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Medchemexpress LLC CP-466722 | 1080622-86-1 | 99.7% | 349.35 | 1 ML
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CP-466722 is a rapidly reversible inhibitor of ATM (IC50 of 0.41 μM). It does not affect PI3K or related PIKK family members. This compound is for research use only. It effectively inhibits IR-induced ATM kinase activity, with this inhibition being rapid and completely reversible.
- Inhibits p53 induction and ATM-dependent phosphorylation in mouse cells.
- Does not inhibit ATR activity.
- Disrupts ATM-dependent cell cycle checkpoints.
- Completely inhibits ATM-dependent phosphorylation in MCF7 cells at 1 μM.
- Reduces pKAP1 phosphorylation in MCF7 cells (IC50 of 0.41 μM at 10 μM).
- Inhibits both pATM and pKAP1 signals.
- Inhibits proliferation of SKBr-3 cancer cells more strongly than MCF-7.
- Slightly increases proportions of MCF-7 and SKBr-3 cells in G1 phase after 48 hours.
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Medchemexpress LLC HY-100518 50mg Medchemexpress, T-26c CAS:869296-13-9 Purity:>98%
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Medchemexpress, HY-100518 50mg T-26c CAS:869296-13-9 T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC 50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Sb-3Ct 10 Mm 1 Ml In Dmso | HY-12354
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Sb-3Ct 10 Mm 1 Ml In Dmso
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Medchemexpress LLC Arn 077 (enantiomer) | 1439366-88-7 | 10MG
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Arn 077 (enantiomer) | 1439366-88-7 | 10MG
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Medchemexpress LLC Au-15330 | 2380274-50-8 | 99.9% | C39H49N9O5S | 10MG
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AU-15330 is a proteolysis-targeting chimera (PROTAC) that selectively degrades SWI/SNF ATPase subunits SMARCA2 and SMARCA4. It demonstrates potent antitumor activity in prostate cancer xenograft models and shows synergy with androgen receptor antagonists in preclinical studies.
- Selective degradation of SMARCA2 and SMARCA4
- Demonstrated antitumor activity in prostate cancer xenograft models
- Synergizes with androgen receptor antagonists
- High reported purity (≈99.9%) suitable for research use
- Solid, off-white to yellow appearance for easy handling
- Storage-stable when kept under recommended conditions
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Medchemexpress LLC Desmethyl erlotinib (OSI-420 free base) | 183321-86-0 | MFCD09841129 | 98.8% | C21H21N3O4 | 10MG
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Desmethyl erlotinib is the primary active metabolite of the epidermal growth factor receptor (EGFR) inhibitor erlotinib. Supplied as a solid research chemical, it is intended for preclinical pharmacology and biochemical studies to investigate EGFR signaling, drug metabolism, and related pharmacodynamic effects.
- High purity suitable for analytical and pharmacological studies.
- Soluble in dimethyl sulfoxide (DMSO); documented in vitro and in vivo formulations available.
- Stable when stored as a powder at -20 °C or 4 °C for recommended storage durations.
- Provided in small-mass quantities appropriate for research applications.
- Synonyms and registry identifiers support cross-referencing in chemical databases.
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Medchemexpress LLC V-9302 | 1855871-76-9 | 99.5% | 538.68 | 100 MG
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V-9302 is a competitive antagonist of transmembrane glutamine flux. It selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) but not ASCT1, inhibiting ASCT2-mediated glutamine uptake in HEK-293 cells.
- Selectively targets the amino acid transporter ASCT2 (SLC1A5) over ASCT1.
- Inhibits glutamine uptake (IC50=9.6 μM) in HEK-293 cells.
- Pharmacological blockade of ASCT2 leads to attenuated cancer cell growth and proliferation, increases cell death, and increases oxidative stress.
- Prevents tumor growth in HCT-116 and HT29 xenograft models (75 mg/kg; i.p.; daily for 21 days).
- When combined with CB-839, it elicits strong growth inhibition in SNU398 and MHCC97H xenograft models.
- High purity: 99.46%.
- Intended for research use only, not for sale to patients.
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eMolecules 1160247-92-6 | Medchem Express | VU 0238429 | 5mg | 446260776 | HY-12157 | MFCD16618396 | 351.281 | C17H12F3NO4
Medchem Express | MK-7246 | 5mg | 446266791 | HY-15853 | 1218918-62-7 | MFCD22741619 | 416.470 | C21H21FN2O4S
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eMolecules 157283-68-6 | Medchem Express | Travoprost | 1mg | 446273021 | HY-B0584 | MFCD03411995 | 500.555 | C26H35F3O6
Ambeed | 5-Bromo-2-chloro-benzoyl chloride | 1g | 595927604 | A801094 | 21900-52-7 | MFCD03208978 | 253.900 | C7H3BrCl2O
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eMolecules 2070014-78-5 | Medchem Express | Mardepodect (hydrochloride) | 5mg | 437899524 | HY-50098A | MFCD30489759 | 428.92 | C25H21ClN4O
Ambeed | 4-(Hydroxymethyl)cyclohexanone | 5g | 525035724 | A131187 | 38580-68-6 | MFCD08056334 | 128.171 | C7H12O2
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eMolecules 2366260-33-3 | Medchem Express | Tubulin inhibitor 11 | 5mg | 788478508 | HY-152156 | 409.5 | C22H23N3O3S
Medchem Express | Boc-D-norleucine | 1g | 721434795 | HY-41912B | 55674-63-0 | MFCD00063168 | 231.292 | C11H21NO4
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Medchemexpress LLC Robustine | 2255-50-7 | 215.20 | 5 MG
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Robustine is a furoquinoline alkaloid isolated from Dictamnus albus. It demonstrates inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.
- Furoquinoline alkaloid
- Inhibits human phosphodiesterase 5 (hPDE5A)
- Purity of 99.70%
- Molecular formula C12H9NO3
- Appears as a white to off-white solid
- Target: PDE5A
- Shipping at room temperature (continental US)
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
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Medchemexpress LLC HY-14875 5mg Medchemexpress, Verucerfont CAS:885220-61-1 Purity:>98%
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Medchemexpress, HY-14875 5mg Verucerfont CAS:885220-61-1 Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000 nM for CRF1, CRF2, and CRF-BP, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 2757254-99-0 | Medchem Express | TP-040 | 5mg | 713706148 | HY-131979 | 286.383 | C15H22N6
ChemScene | 99-Spirobi[fluorene]-22-diamine | 100mg | 632296562 | CS-0155955 | 67665-45-6 | MFCD16038515 | 346.433 | C25H18N2
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