Phenoxy compounds

Organic compounds that have one or more phenyl groups that are bonded to an oxygen with a radical electron; includes compounds with additional substitutions.

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1,186 – 1,200 of 2,716 results

1,186

Medchemexpress LLC JAK-IN-5 hydrochloride | 2751323-21-2 | 99.9% | 511.03 g/mol | C27H32ClFN6O | 5 MG

JAK-IN-5 hydrochloride is the hydrochloride salt of a Janus kinase (JAK) inhibitor disclosed in patent US20170121327A1 (compound example 283). Supplied for research use, it is characterized by high purity, defined solubility properties, and recommended storage conditions suitable for biochemical and cellular studies.

High purity: 99.86% (analytical grade).
Hydrochloride salt form for improved stability and handling.
Soluble in DMSO (5 mg/mL); sparingly soluble in water (0.5 mg/mL; sonication or warming may be required).
Storage: 4°C sealed; in solution: -80°C (6 months), -20°C (1 month).
Intended for research use as a JAK family kinase inhibitor.
Molecular weight 511.03 g/mol; molecular formula C27H32ClFN6O.

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1,187

eMolecules 926023-82-7 | Medchem Express | AMTB (hydrochloride) | 5mg | 686921644 | HY-100345 | MFCD18086917 | 430.99 | C23H27ClN2O2S

Medchem Express | AMTB (hydrochloride) | 5mg | 686921644 | HY-100345 | 926023-82-7 | MFCD18086917 | 430.990 | C23H27ClN2O2S

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1,188

Medchemexpress LLC Lucitanib | 1058137-23-7 | C26H25N3O4 | 100 MG

Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR, potently and selectively inhibiting multiple receptors. It is suitable for use in various laboratory applications, including the manufacture of substances.

Inhibits VEGFR1 with an IC50 of 7 nM
Inhibits VEGFR2 with an IC50 of 25 nM
Inhibits VEGFR3 with an IC50 of 10 nM
Inhibits FGFR1 with an IC50 of 17.5 nM
Inhibits FGFR2 with an IC50 of 82.5 nM
Targeted for cancer research

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1,189

Medchemexpress LLC 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide | 887936-68-7 | 98.9% | 436.50 g/mol | C24H28N4O4 | 100 MG

Temanogrel is a research-grade small molecule that acts as a highly selective antagonist of the serotonin 5-HT2A receptor (reported Ki = 4.9 nM). Supplied as a solid powder for in vitro and preclinical research, it is provided at high purity for biochemical and pharmacological studies.

Highly selective 5-HT2A receptor antagonist (Ki = 4.9 nM).
Intended for research use only; not for human therapeutic use.
High purity (98.94%) solid powder, white to light yellow.
Molecular formula C24H28N4O4; molecular weight 436.50 g/mol.
Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent store at -80°C (6 months) or -20°C (1 month).
Available in small milligram pack sizes suitable for laboratory studies.

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1,190

Medchemexpress LLC Epertinib hydrochloride | 2071195-74-7 | 98.2% | 596.48 g/mol | C30H28Cl2FN5O3 | 100 MG

Epertinib hydrochloride is the hydrochloride salt of epertinib, a potent, orally active, reversible, and selective inhibitor of EGFR, HER2, and HER4. It is provided for preclinical research to evaluate signaling pathways and antitumor efficacy and is compatible with click-chemistry applications because of an alkyne functional group.

Potent, selective tyrosine kinase inhibitor of EGFR, HER2, and HER4.
Used in preclinical antitumor and signaling research.
Contains an alkyne moiety compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC).
Supplied as a light yellow to yellow solid with high purity.
Stable under recommended storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
Molecular weight 596.48 g/mol; molecular formula C30H28Cl2FN5O3.

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1,191

Selleck Chemical LLC Erdafitinib

Erdafitinib is a potent and selective orally bioavailable pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity Erdafitinib also binds to RET (c-RET) CSF-1R PDGFR- /PDGFR- FLT4 Kit (c-Kit) and VEGFR-2 and induces cellular apoptosis

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1,192

Medchemexpress LLC Tucatinib hemiethanolate | 1429755-56-5 | 98.8% | 503.57 | 50 MG

Tucatinib hemiethanolate is a potent, orally active, and selective HER2 inhibitor. It demonstrates nanomolar activity against purified HER2 enzyme and is approximately 500-fold selective for HER2 versus EGFR in cell-based assays. It selectively inhibits the receptor tyrosine kinase HER2 relative to EGFR, blocking proliferation and phosphorylation of HER2 and its downstream effector, Akt in HER2 overexpressing cell lines. It is intended for research use only.

Potent and selective HER2 inhibition (IC50 of 8 nM)
Antiproliferative effects in HER2 overexpressing cell lines
Reduced EGFR-related toxicities
Anti-tumor activity and survival benefit in animal models
Significant reduction in brain pErbB2 (80%)
Dose-related tumor growth inhibition
Enhanced tumor growth inhibition when combined with trastuzumab
Studied in various clinical trials

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1,193

Medchemexpress LLC HY-15729A 5mg Medchemexpress, Rociletinib hydrobromide CAS:1446700-26-0 Purity:>98%

Medchemexpress, HY-15729A 5mg Rociletinib hydrobromide CAS:1446700-26-0 Rociletinib hydrobromide (CO-1686 hydrobromide) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,194

Medchemexpress LLC 2-(5-cyclopropyl-1-(4-ethoxy-2,6-difluorobenzyl)-4-methylpyrazol-3-yl)-5-methoxy-N-(4-pyridyl)pyrimidin-4-amine | 1445830-50-1 | 492.52 g·mol⁻¹ | C26H26F2N6O2 | 100 MG

BAY-320 is a selective, ATP-competitive inhibitor of the Bub1 serine/threonine kinase supplied as a solid for research use. It inhibits Bub1 with a reported IC50 of about 680 nM and is used to study mitotic chromosome arrangement, spindle assembly, and cancer cell proliferation. The compound is provided as a powder with recommended low-temperature storage for long-term stability.

Selective ATP-competitive Bub1 kinase inhibitor.
Reported IC50 ~680 nM against Bub1.
Solid powder suitable for biochemical and cellular assays.
Molecular weight 492.52 g·mol⁻¹; formula C26H26F2N6O2.
Recommended storage: powder -20 °C (3 years), 4 °C (2 years).
Useful for studies of mitosis and cancer cell proliferation.

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1,195

Medchemexpress LLC Schisandrin C | 61301-33-5 | MFCD00078864 | 384.42 | 50 MG

Schisandrin C, also known as Schizandrin-C or Wuweizisu-C, is a bioactive lignan derived from *Schisandra chinensis*. It is noted for its diverse biological activities, including anticancer, anti-inflammatory, and antioxidant effects. This phytochemical induces cell apoptosis and is investigated for its potential in treating cancer, Alzheimer's disease, and liver diseases. It is a phytochemical lignan isolated from *Schizandra chinensis* and can be utilized in research pertaining to cancer, Alzheimer's disease, and liver diseases.

Source: Phytochemical lignan isolated from *Schizandra chinensis*.
Biological activities: Anticancer, anti-inflammatory, and antioxidant effects.
Research applications: Used in research for cancer, Alzheimer's disease, and liver diseases.
Mechanism of action: Induces cell apoptosis.
Purity: 99.95%.
Appearance: Solid, white to off-white.

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1,196

Medchemexpress LLC HY-12026 100mg , WZ4002 CAS:1213269-23-8 Purity:98%

Medchemexpress, HY-12026 100mg WZ4002 CAS:1213269-23-8 Formula:C25H27ClN6O3 IC50: 2 nM (EGFR L858R ), 8 nM (EGFR L858R/T790M ), 3 nM (EGFR E746_A750 ), 2 nM (EGFR E746_A750/T790M ) Purity:98% WZ4002 is a mutant selective EGFR inhibitor with IC 50 s of 2, 8, 3 and 2 nM for EGFR L858R , EGFR L858R/T790M , EGFR E746_A750 and EGFR E746_A750/T790M , respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,197

Medchemexpress LLC HY-16901 10mg Medchemexpress, Firsocostat CAS:1434635-54-7 Purity:>98%

Medchemexpress, HY-16901 10mg Firsocostat CAS:1434635-54-7 Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,198

eMolecules 34394-11-1 | 14-Nonacosanone | Toronto Research Chemicals422.782 | C29H58OCCCCCCCCCCCCCCCC(=O)CCCCCCCCCCCCC | 100mg | 601599332

14-Nonacosanone | Toronto Research Chemicals | 34394-11-1422.782 | C29H58OCCCCCCCCCCCCCCCC(=O)CCCCCCCCCCCCC | 100mg | 601599332

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1,199

Medchemexpress LLC Acoramidis Hydrochloride 100Mg | HY-109165A-100MG

Acoramidis Hydrochloride 100Mg

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1,200

Selleck Chemical LLC Pacritinib

Pacritinib is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays respectively Phase 3

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Phenoxy compounds

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Medchemexpress LLC JAK-IN-5 hydrochloride | 2751323-21-2 | 99.9% | 511.03 g/mol | C27H32ClFN6O | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lucitanib | 1058137-23-7 | C26H25N3O4 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide | 887936-68-7 | 98.9% | 436.50 g/mol | C24H28N4O4 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Epertinib hydrochloride | 2071195-74-7 | 98.2% | 596.48 g/mol | C30H28Cl2FN5O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tucatinib hemiethanolate | 1429755-56-5 | 98.8% | 503.57 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-15729A 5mg Medchemexpress, Rociletinib hydrobromide CAS:1446700-26-0 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Schisandrin C | 61301-33-5 | MFCD00078864 | 384.42 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-12026 100mg , WZ4002 CAS:1213269-23-8 Purity:98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-16901 10mg Medchemexpress, Firsocostat CAS:1434635-54-7 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Acoramidis Hydrochloride 100Mg | HY-109165A-100MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More