Phenoxy compounds
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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences LY344864 hydrochloride >=98% (HPLC) | 1217756-94-9 | 5MG
LY344864 hydrochloride >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 387.88 | 1217756-94-9 | 5MG
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Medchemexpress LLC HY-12381 5mg Medchemexpress, ML224 CAS:1338824-21-7 Purity:>98%
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Medchemexpress, HY-12381 5mg ML224 CAS:1338824-21-7 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Repaglinide Related Compound B United States Pharmacopeia (USP) Reference Standard | 99469-99-5 | 50MG
Repaglinide Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 252.26 | 99469-99-5 | 50MG
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Medchemexpress LLC HY-14710 10mg Medchemexpress, AZ3146 CAS:1124329-14-1 Purity:>98%
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Medchemexpress, HY-14710 10mg AZ3146 CAS:1124329-14-1 AZ3146 is a reasonably potent and selective Mps1 inhibitor with IC50 of 35 nM for Mps1Cat. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Levomepromazine hydrochloride European Pharmacopoeia (EP) Reference Standard | 1236-99-3 |
Levomepromazine hydrochloride European Pharmacopoeia (EP) Reference Standard | Mol Wt: 364.93 | 1236-99-3 |
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Medchemexpress LLC Prexasertib dimesylate | 1234015-58-7 | MFCD32693943 | 98.9% | 557.60 | C20H27N7O8S2 | 10 MG
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Prexasertib dimesylate is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor supplied as a solid research compound. It causes double-stranded DNA breakage and replication catastrophe that lead to apoptosis, and is offered in multiple solid pack sizes and solution formats for laboratory use. Not for human or clinical use.
- Selective ATP-competitive CHK1 inhibitor.
- Induces DNA double-strand breaks and replication catastrophe.
- High purity: 98.9%.
- Available as solid and as 10 mM solution in DMSO.
- Solubility data provided for in vitro and in vivo protocols.
- Recommended storage: 4°C (solid) and -80°C for stock solutions.
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Aobchem AOBCHEM
5001065605 METHYL 4-PHENOXY-2-BUTYNOATE 1
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Medchemexpress LLC HY-15392 10mg , Chroman 1 ROCK-II inhibitor CAS:1273579-40-0 Purity:98%
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Medchemexpress, HY-15392 10mg Chroman 1 ROCK-II inhibitor CAS:1273579-40-0 Formula:C24H28N4O4 IC50: < 1 nM (ROCK2) Purity:98% Chroman 1 is a highly potent ROCK2 inhibitor, with an IC 50 of < 1 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Biotium MTSPS 100MG
MTSPS 100MG
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Chem-Impex International, Inc. 2-Ethoxyphenylacetic acid | MFCD00016824 | 5G
2-Ethoxyphenylacetic acid, MFCD00016824, 5G
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Chem-Impex International, Inc. o-Phenyl chlorothiocarbonate | MFCD00004920 | 25G
o-Phenyl chlorothiocarbonate, MFCD00004920, 25G
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Sigma Aldrich Fine Chemicals Biosciences Pindolol >=98% (TLC), powder | 13523-86-9 | MFCD00010530 | 250MG
Pindolol >=98% (TLC), powder | Purity: >=98% (TLC) | Mol Wt: 248.32 | 13523-86-9 | MFCD00010530 | 250MG
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Sigma Aldrich Fine Chemicals Biosciences Neostigmine methyl sulfate | 51-60-5 | MFCD00011796 | 1 g
Neostigmine methyl sulfate | Mol Wt: 334.39 | 51-60-5 | MFCD00011796 | 1 g
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Sigma Aldrich Fine Chemicals Biosciences PF-8380 >=98% (HPLC) | 1144035-53-9 | 5MG
PF-8380 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 478.33 | 1144035-53-9 | 5MG
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Medchemexpress LLC Prexasertib (dimesylate) | 1234015-58-7 | 98.9% | 557.60 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Prexasertib dimesylate is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. It also inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). This compound induces double-stranded DNA breakage and replication catastrophe, leading to apoptosis, and demonstrates potent anti-tumor activity.
- Selective, ATP-competitive CHK1 inhibitor
- Inhibits CHK1 (Ki 0.9 nM, IC50 <1 nM), CHK2, and RSK1
- Induces double-stranded DNA breakage and replication catastrophe
- Leads to apoptosis and potent anti-tumor activity
- Inhibits MELK, SIK, BRSK2, and ARK5
- Requires CDC25A and CDK2 for DNA damage
- Causes DNA damage during S-phase
- Inhibits CHK1 and CHK2 autophosphorylation
- Induces cell-cycle shift with H2AX phosphorylation
- Triggers chromosomal fragmentation and replication stress
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