Phenylhydrazines
Medchemexpress LLC M-PEG3-0-benzaldehyde | 153364-63-7 | C14H20O5 | 5 G
M-PEG3-0-benzaldehyde is a PEG-based PROTAC linker. PROTACs contain two different ligands connected by a linker, with one ligand for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Utilizes the ubiquitin-proteasome system for selective protein degradation
Medchemexpress LLC Tetracycline hydrochloride | 64-75-5 | 98.7% | 25 G
Tetracycline hydrochloride is a broad-spectrum antibiotic with oral activity, effective against a wide range of bacteria, including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, and rickettsiae. It is suitable for research on infections.
- Broad-spectrum antibiotic
- Oral activity
- Active against gram-positive and gram-negative bacteria
- Inhibits L-amyloid aggregates
- Disassembles pre-formed fibrils
eMolecules 635-26-7 | o-Tolylhydrazine hydrochloride | Ambeed | MFCD00012925 | 158.630 | C7H11ClN2 | 97.000 | Cl.Cc1ccccc1NN | 1g | 570567247
o-Tolylhydrazine hydrochloride | Ambeed | 635-26-7 | MFCD00012925 | 158.630 | C7H11ClN2 | 97.000 | Cl.Cc1ccccc1NN | 1g | 570567247
Medchemexpress LLC Hydrastinine hydrochloride | 4884-68-8 | MFCD09763656 | 99.4% | 243.69 g·mol⁻1 | C11H14ClNO3 | 10 MG
Hydrastinine hydrochloride is the hydrochloride salt of hydrastinine, an alkaloid found in goldenseal (Hydrastis canadensis). It is supplied for research and analytical use and is reported to have haemostatic activity. The product is offered in solid form and as DMSO solutions, with purity levels suitable for analytical and pharmacological studies.
- High purity (~99.4%), suitable for analytical applications.
- Available as solid and as 10 mM solutions in DMSO.
- Reported haemostatic activity used in pharmacology research.
- Supplied for research and analytical purposes only, not for human use.
- Key identifiers: CAS 4884-68-8, formula C11H14ClNO3, molecular weight 243.69 g·mol⁻1.
Medchemexpress LLC (+)-Niguldipine hydrochloride | 113145-69-0 | MFCD00873564 | 98.1% | 646.17 g/mol | C36H40ClN3O6 | 1 MG
(+)-Niguldipine hydrochloride is the S-enantiomer of niguldipine, a dihydropyridine calcium channel antagonist used in research to probe L-type calcium channel-mediated signaling and vasodilation mechanisms. It is supplied as an off-white to yellow solid with high purity for laboratory applications.
- High purity suitable for analytical and biological assays.
- S-enantiomer useful for enantiospecific pharmacology studies.
- Small vials appropriate for screening and mechanistic experiments.
- Off-white to yellow solid form simplifies handling and formulation.
- Storage recommendations provided for sealed samples and solvent solutions.
Medchemexpress LLC Valacyclovir hydrochloride | 124832-27-5 | 98.7% | 360.80 | 50 MG
Valacyclovir hydrochloride is an orally active antiviral agent effective against herpes simplex, herpes zoster, and herpes B. It inhibits HSV-1 with an IC50 of 2.9 μg/mL and is a prodrug of Aciclovir.
- Administered once a day
- Effective for treating recurrences of genital herpes
- 1 g daily dose as effective as 2 g daily for recurrences
Chemscene ChemScene | (4-Fluorophenyl)hydrazine | 10G | CS-0183141 | 0.96 | 371-14-2| MFCD00041262 | 126.13
ChemScene | (4-Fluorophenyl)hydrazine | 10G | CS-0183141 | 0.96 | 371-14-2| MFCD00041262 | 126.13
Medchemexpress LLC Pioglitazone hydrochloride | 112529-15-4 | 100.0% | C19H21ClN2O3S | 5 G
Pioglitazone hydrochloride is a potent and selective PPARγ agonist, commonly used in research for ferroptosis, metabolic disease, and cancer. It impacts cellular processes through various pathways including cell cycle/DNA damage, metabolic enzyme/protease, vitamin D related/nuclear receptor, and apoptosis.
- Functions as a potent and selective PPARγ agonist.
- Known by synonyms U 72107A and AD 4833.
- Explored in research areas such as PPAR, ferroptosis, metabolic disease, and cancer.
- Affects pathways including cell cycle/DNA damage, metabolic enzyme/protease, vitamin D related/nuclear receptor, and apoptosis.
- Demonstrates activity with human PPARδ and PPARα.
- Cited in 42 publications.
Medchemexpress LLC JBSNF-000028 hydrochloride | C11H14ClN3 | 100 MG
JBSNF-000028 hydrochloride is an orally active small molecule inhibitor of tricyclic nicotinamide N-methyltransferase (NNMT), with IC50 values for human, mouse, and monkey NNMT of 33, 210, and 190 nM, respectively. It reduces endogenous MNA levels in U2OS cells (EC50 2.5 μM) and shows significant anti-obesity and anti-diabetic activities in the diet-induced obesity (DIO) model. It is suitable for studying metabolic diseases like obesity, type 2 diabetes, and non-alcoholic fatty liver disease.
- Inhibits NNMT activity in U2OS cells (EC50 2.5 μM).
- Shows no cytotoxicity against HepG2 cells at 10-100 μM.
- Binds below a hairpin structural motif at the nicotinamide pocket.
- Inactive against a broad panel of metabolism-related targets.
- Improves glucose and lipid handling in mice with diet-induced obesity.
- Enhances glucose tolerance in NNMT knockout DIO mice.
Medchemexpress LLC Procainamide hydrochloride | 614-39-1 | 99.5% | C13H22ClN3O | 1 mL
Procainamide hydrochloride is a specific and potent inhibitor of DNA methyltransferase 1 (DNMT1). It reactivates the expression of tumor suppressor factors by demethylating tumor suppressor genes, and can induce vacuolization in various cell types, reducing cell proliferation and migration. It also relaxes airway smooth muscle by activating potassium channels. This product is suitable for use in cancer and arrhythmia research.
- Specific and potent inhibitor of DNA methyltransferase 1
- Reactivates tumor suppressor gene expression
- Induces cellular vacuolization
- Reduces cell proliferation and migration
- Relaxes airway smooth muscle
- Causes loss of CpG methylation
- Demethylates ER, p16, and RAR genes
- Useful in cancer research
- Useful in arrhythmia research