Phenylhydrazines
eMolecules ChemScene (2-Methoxy-6-methylphenyl)boronic acid 250mg 632281936 CS-0146708 0 000 1567218-43-2 MFCD11043444 165 980 C8H11BO3
ChemScene (2-Methoxy-6-methylphenyl)boronic acid 250mg 632281936 CS-0146708 0 000 1567218-43-2 MFCD11043444 165 980 C8H11BO3
Medchemexpress LLC AG-636 | 1623416-31-8 | 98.07% | 343.38 | 1 ML
AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor. With an IC50 of 17 nM, it demonstrates strong anticancer effects and growth-inhibitory activity in various cancer cell lines. It has also shown robust tumor growth inhibition in xenograft lymphoma models.
- Potent, reversible, selective, and orally active DHODH inhibitor
- IC50 of 17 nM against DHODH
- Strong growth-inhibitory activity in cancer cell lines of hematologic versus solid tumor origin
- Robust tumor growth inhibition in xenograft lymphoma models
- Currently in phase 1 clinical trial for lymphoma
Medchemexpress LLC Pipendoxifene hydrochloride | 245124-69-0 | 99.8% | 493.04 | 25 MG
Pipendoxifene hydrochloride is a selective estrogen receptor modulator (SERM) intended for breast cancer research. This 2-phenyl indole SERM demonstrates an excellent preclinical pharmacological profile, making it a candidate for further development as a treatment for metastatic breast cancer.
- Purity: 99.83%
- Appearance: Solid
- Color: White to yellow
- Target: Estrogen receptor
- Molecular weight: 493.04
- Solubility in DMSO: 100 mg/mL
- Involved in a clinical trial for breast cancer (NCT00006369)
- Recommended storage: 4°C, sealed, away from moisture; in solvent: -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Idalopirdine hydrochloride | 467458-02-2 | 99.6% | C20H20ClF5N2O | 100 MG
Idalopirdine hydrochloride is a potent and selective 5-HT6 receptor antagonist with a Ki value of 0.83 nM. It is primarily used in research studies related to Alzheimer's disease and schizophrenia. It has shown to reduce food intake and body weight in over-eating rat models, and enhance cortical gamma oscillations.
- Potent and selective 5-HT6 receptor antagonist
- Ki value of 0.83 nM
- Used in studies of Alzheimer's disease and schizophrenia
- Reduces food intake and body weight in over-eating rat models
- Enhances cortical gamma oscillations
- Suitable for neurological and neurodegenerative disease research
Medchemexpress LLC Eflornithine hydrochloride | 68278-23-9 | 99.9% | 500 MG
Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. It is used as a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
- Specific, irreversible inhibitor of ornithine decarboxylase
- Treats African trypanosomiasis
- Reduces excessive facial hair growth in women
- Shown to normalize contractile intensity in hypertensive rats
Medchemexpress LLC Clomipramine hydrochloride | 17321-77-6 | 99.6% | 1 G
Clomipramine hydrochloride is a potent 5-HT reuptake blocker (IC50 = 1.5 nM) and a tricyclic antidepressant. It is utilized in research for depression and obsessive-compulsive disorder (OCD).
- Potent 5-HT reuptake blocker
- Tricyclic antidepressant for research
- Inhibits noradrenaline and 5-HT reuptake
- Interferes with autophagic flux
- Reduces autophagy in neuronal cultures
- Decreases immobility in forced swimming tests
- Inhibits marble burying behavior in OCD animal models
- Decreases autophagic flux in murine tissues
Medchemexpress LLC Tetracycline hydrochloride | 64-75-5 | 98.7% | 250 MG
Tetracycline hydrochloride is a broad-spectrum antibiotic with oral activity. It is effective against a variety of gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, and rickettsiae. This product is intended for research use only.
- Broad-spectrum antibiotic with oral activity
- Effective against gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, and rickettsiae
- Can be used for the research of infections
- Inhibits L-amyloid aggregates formation and disassembles pre-formed fibrils
- Applicable in animal modeling to create genetically engineered disease models
- Induces tumor regression based on BCR-ABL gene silencing
Medchemexpress LLC Pipendoxifene hydrochloride | 245124-69-0 | 99.8% | C29H33ClN2O3 | 10MG
Pipendoxifene hydrochloride is a selective estrogen receptor modulator (SERM) used in preclinical research, including studies of breast cancer. Supplied as the hydrochloride salt, it is a white to yellow solid with high measured purity and recommended sealed storage to maintain stability. The compound is intended for research use and is provided with supporting safety documentation.
- Selective estrogen receptor modulator for ER-targeted studies.
- High purity suitable for research applications.
- White to yellow solid form for convenient handling.
- Multiple small-scale pack sizes available for screening.
- Stable when stored sealed at recommended temperatures.
- Provided with safety data sheet and technical information.
Medchemexpress LLC Almonertinib hydrochloride | 2134096-03-8 | 98.9% | 562.11 | 100 MG
Almonertinib hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows significant inhibitory activity against T790M, T790M/L858R, and T790M/Del19 (IC50: 0.37, 0.29, and 0.21 nM, respectively) and is less effective against wild type (3.39 nM). It is used for the research of non-small cell lung cancer.
- Orally available
- Irreversible
- Third-generation EGFR tyrosine kinase inhibitor
- High selectivity for EGFR-sensitizing and T790M resistance mutations
- Significant inhibitory activity against T790M, T790M/L858R, and T790M/Del19
- Effective against other EGFR sensitive mutations including G719X, del19, L858R, and L861Q
eMolecules 502496-26-6 | 2,6-Difluorophenylhydrazine hydrochloride | Oakwood Chemical | MFCD03094169 | 180.580 | C6H7ClF2N2 | 95.000 | Cl.NNc1c(F)cccc1F | 1g | 537716019
2,6-Difluorophenylhydrazine hydrochloride | Oakwood Chemical | 502496-26-6 | MFCD03094169 | 180.580 | C6H7ClF2N2 | 95.000 | Cl.NNc1c(F)cccc1F | 1g | 537716019
eMolecules 5300-03-8 | 9-cis-Retinoic Acid | AA Blocks LLC | MFCD00270072 | 300.442 | C20H28O2 | CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O | 1mg | 586011463
9-cis-Retinoic Acid | AA Blocks LLC | 5300-03-8 | MFCD00270072 | 300.442 | C20H28O2 | CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O | 1mg | 586011463
Medchemexpress LLC CDK4/6-IN-15 (hydrochloride) | 99.0% | C21H28ClFN8S | 25 MG
CDK4/6-IN-15 hydrochloride is an orally active and selective CDK4/6 inhibitor. It is used for research purposes to study cancer cell growth, specifically by inhibiting cell proliferation and arresting the cell cycle at the G1 phase. This compound suppresses retinoblastoma tumor suppressor protein (Rb) phosphorylation and E2 factor (E2F)-regulated gene expression.
- Orally active and selective CDK4/6 inhibitor.
- Inhibits cancer cell growth by arresting the cell cycle at G1 phase.
- Suppresses retinoblastoma tumor suppressor protein (Rb) phosphorylation at S780.
- Triggers apoptosis in MV4-11 and MDA-MB-453 cells.
- Potently inhibits FLT3 and MYLK4.
eMolecules 5870-29-1 | Medchem Express | Cyclopentolate (hydrochloride) | 10mg | 527573824 | HY-B1621A | MFCD00079048 | 327.85 | C17H26ClNO3
Medchem Express | Cyclopentolate (hydrochloride) | 10mg | 527573824 | HY-B1621A | 5870-29-1 | MFCD00079048 | 327.850 | C17H26ClNO3
Aobchem (4-Bromo-2-fluoro-5-methylphenyl)(methyl)sulfane | 97% | CAS 1011460-51-7 | C8H8BrFS | 5g
(4-Bromo-2-fluoro-5-methylphenyl)(methyl)sulfane | 97% | CAS 1011460-51-7 | C8H8BrFS | 5g
Medchemexpress LLC Pexidartinib (hydrochloride) | 2040295-03-0 | 99.8% | 454.28 | 1 G
Pexidartinib (hydrochloride) | 2040295-03-0 | 99.8% | 454.28 | 1 G