Phthalic acid and derivatives
AdipoGen Pifithrin-alpha cyclic HBr
Chemical. CAS 511296-88-160477-34-1 free base. Formula C16H16N2S . HBr. MW 268.4 . 80.9. Stable analog of pifithrin-alpha. p53 inhibitor.
Santa Cruz Biotechnology ETHYLENE TEREPHTHALATE CYCLIC
Ethylene Terephthalate Cyclic Trimer| Mol Wt: 576.50 | 7441-32-9 | 5 mg
Medchemexpress LLC Olsalazine (disodium) | 6054-98-4 | 99.8% | 10 G
Olsalazine Disodium is an orally active prodrug of 5-ASA. It is utilized in research for cancer, inflammation, and metabolic diseases, including colorectal cancer, inflammatory bowel disease (IBD), and hyperuricemia. This compound can inhibit cell proliferation, induce apoptosis, reduce DAI and MPO activity, and inhibit inflammatory cytokine levels.
- Orally active prodrug of 5-ASA
- Inhibits cell proliferation
- Induces apoptosis
- Reduces DAI and MPO activity
- Inhibits inflammatory cytokine levels
- Suitable for research in cancer
- Suitable for research in inflammation
- Suitable for research in metabolic diseases
Cayman Chemical 6-CarboxyfluoresceIn 1g
A single isomer derivative of 5(6)-carboxyfluorescein that can be used to fluorescently label biomolecules; excitation/emission maxima of 492 and 518 nm, respectively
Medchemexpress LLC 1,4-Benzenedicarboxylic acid | 100-21-0 | 99.9% | 166.13 | 10 G
Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. It can also be utilized to build skin tumor models.
- Can be used in animal modeling to create skin tumor models.
- It is metabolized in the body to form calcium terephthalate or calcium hydrogen terephthalate, which can lead to bladder stone formation.
- The lithogenic effect is more pronounced in weanling mice at higher doses.
- Promotes excessive cell proliferation and induces skin tumor formation by disrupting the p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway.
- Specific modeling methods for skin tumor induction involve topical application in C57BL/6 mice.
Medchemexpress LLC Terephthalic acid-13C2 | 121191-53-5 | 99.6% | 168.12 | 100 MG
Terephthalic acid-13C2 is the 13C-labeled version of Terephthalic acid, an isomer and precursor of polyester PET. It can also be used to create skin tumor models.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during drug development
- Deuteration can potentially affect the pharmacokinetic and metabolic profiles of drugs
Cayman Chemical 6-CarboxyfluoresceIn 500mg
A single isomer derivative of 5(6)-carboxyfluorescein that can be used to fluorescently label biomolecules; excitation/emission maxima of 492 and 518 nm, respectively
Medchemexpress LLC Disodium 5'-inosinate (IMP disodium salt) | 4691-65-0 | 99.74% | 100 G
Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice.
- Responds to oral stimulation in rat solitary-tract nucleus neurons and is involved in encoding umami taste.
- Produced a behavioral excitement in mice showing an increased movement, jumping and squeaking in response to tactile stimuli and enhanced preening and increased reflex response.
Medchemexpress LLC Disodium 5'-inosinate | 4691-65-0 | 99.7% | 25 G
Disodium 5'-inosinate is a nucleotide-based umami agent. It can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, it produces a transient behavioral excitement in mice.
- Responds to oral stimulation in rat solitary-tract nucleus neurons, involved in encoding umami taste.
- Produces transient behavioral excitement in mice.
- In mice (500 mg/kg, intravenous injection), it led to increased movement, jumping, squeaking, enhanced preening, and increased reflex response, with sedation after 60 minutes.
Cayman Chemical 5 6-CarboxyfluoresceIn 1g
A mixture of 5-carboxy and 6-carboxy derivatives of fluorescein; used to label biomolecules through a reaction involving the carboxyl group; membrane impermeant, with applications in studies of membrane permeability
Medchemexpress LLC Terephthalic acid-13C2 | 121191-53-5 | 99.6% | 168.12 | 25 MG
Terephthalic acid-13C2 is the 13C-labeled version of Terephthalic acid. Terephthalic acid is an isomer and a precursor of polyester PET, which is used in clothing and plastics. It can also be utilized to create skin tumor models.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.
- Stable heavy isotopes, such as carbon-13 (13C), are incorporated into drug molecules primarily as tracers for quantification during drug development.
Accela Chembio Inc 2 | 5-dibromoterephthalic Acid | 100g | 13731-82-3 | MFCD00204593 | 97+% | Shelf Life: 900 Days | Light Sensitive
2 | 5-dibromoterephthalic Acid | 100g | 13731-82-3 | MFCD00204593 | 97+% | Shelf Life: 900 Days | Light Sensitive
TARGETMOL CHEMICALS INC L-2-Hydroxyglutaric acid disod
Also available in 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively). Purity ≥98%
Medchemexpress LLC Disodium terephthalate | 10028-70-3 | MFCD00013137 | 99.9% | 210.09 g/mol | C8H4Na2O4 | 10 G
Disodium terephthalate is the disodium salt of terephthalic acid supplied as a high-purity research chemical for laboratory use. It serves as a building block and precursor in polyester (PET) synthesis and is used as a reagent in biochemical assays and model systems. The material is provided as a fine solid with defined analytical properties suitable for both analytical and preparative applications.
- High purity: 99.93%
- Molecular formula C8H4Na2O4; molecular weight 210.09 g/mol
- Solid form suitable for analytical and preparative work
- Applications include polyester precursor and biochemical assay reagent
- Available in small pack sizes for laboratory research, e.g. 10 G
Medchemexpress LLC Fosbretabulin disodium | 168555-66-6 | 99.9% | 440.29 | 1 MG
Fosbretabulin disodium (CA 4DP) is a tubulin destabilizing agent. It is a Combretastatin A4 proagent that selectively targets endothelial cells, induces regression of nascent tumor neovessels, reduces tumor blood flow, and causes central tumor necrosis.
- Tubulin destabilizing agent
- Selectively targets endothelial cells
- Induces regression of nascent tumor neovessels
- Reduces tumor blood flow
- Causes central tumor necrosis
- For research use only