Aminophenols
Selleck Chemical LLC 3-Hydroxybenzoic acid
3-Hydroxybenzoic acid (m-Hydroxybenzoic acid 3-Carboxyphenol m-Salicylic acid) is used as an intermediate in the synthesis of plasticisers resins pharmaceuticals etc
Cayman Chemical Methylhexanamine hydrochlori
A simple aliphatic amine that was once marketed as a nasal decongestant but is now sold as a bodybuilding supplement; sold as a mild stimulant in the form of party pills; intended for forensic or research purposes
Medchemexpress LLC BODIPY-581/591 NHS ester | 150152-70-8 | 98.67% | 489.28 | 5 MG
BODIPY-581/591 NHS ester is a bright, red fluorescent dye used for the labeling of amine containing biomolecules. It exhibits excitation at 581 nm and emission at 591 nm.
- It is a bright, red fluorescent dye.
- It has an excitation wavelength of 581 nm.
- It has an emission wavelength of 591 nm.
- It can be used for labeling biomolecules that contain amine groups.
Medchemexpress LLC His-Pro hydrochloride | 2415727-78-3 | 99.8% | 288.73 | 50 MG
His-Pro (Histidyl-proline) hydrochloride is a dipeptide consisting of histidyl and proline. It is for research use only and not sold to patients.
- Solid appearance
- White to off-white color
- Ships at room temperature in continental US
- Sealed storage, away from moisture and light
- Powder stable at -80°C for 2 years, -20°C for 1 year
- In solvent stable at -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Fasudil hydrochloride | 105628-07-7 | MFCD00943198 | 100.0% | 327.83 | C14H18ClN3O2S | 5 G
Fasudil hydrochloride is the monohydrochloride salt of fasudil, a small-molecule RhoA/ROCK inhibitor used in biochemical and cellular research to modulate kinase signaling. It is supplied as a solid powder with high stated purity and is suitable for in vitro assays and biochemical studies.
- RhoA/ROCK inhibitor used in kinase and cellular assays
- Monohydrochloride salt, solid powder
- High stated purity (99.97%) for analytical and research use
- Molecular formula: C14H18ClN3O2S; molecular weight: 327.83 g/mol
- Suitable for biochemical assays and cell-based studies
- Available in laboratory-scale pack sizes, including 5 g
Medchemexpress LLC MRE-269-d7 | 1265295-20-2 | 99.6% | C25H22D7N3O3 | 5 MG
MRE-269-d7 is a deuterium-labeled version of MRE-269, an active metabolite of selexipag that acts as a selective IP receptor agonist. It is intended for research use and can serve as a tracer and an internal standard for quantitative analysis. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled version of MRE-269
- Active metabolite of selexipag
- Selective IP receptor agonist
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 5 MG
Hypidone hydrochloride is a research-grade, orally active antidepressant used in preclinical pharmacology to study serotonergic mechanisms. It functions as a selective serotonin uptake inhibitor and a potent 5-HT1A receptor agonist, showing low-nanomolar activity in uptake and receptor assays. Supplied as a white to off-white solid with high purity for laboratory use.
- Orally active antidepressant with dual mechanism of action.
- Highly potent 5-HT uptake inhibitor and 5-HT1A receptor agonist.
- High purity suitable for preclinical research.
- Available in small milligram package sizes and DMSO solution format.
- Soluble in DMSO and supplied with recommended storage conditions.
![Medchemexpress LLC N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine HCl | 169505-93-5 | 99.9% | 449.41 | C24H30Cl2N2O2 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211386.png-250.jpg)
Medchemexpress LLC N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine HCl | 169505-93-5 | 99.9% | 449.41 | C24H30Cl2N2O2 | 1 ML
A selective α1A adrenoceptor antagonist supplied as a ready-to-use 10 mM solution in DMSO for in vitro pharmacology and receptor signaling studies. Demonstrates high potency and is provided at high purity for research applications.
- Supplied as a 10 mM solution in DMSO, 1 mL.
- High potency: pKi 9.1 and pA2 9.8.
- High purity: 99.9%.
- Molecular weight: 449.41.
- CAS number: 169505-93-5.
- Storage: store sealed, away from moisture; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC ZZW-115 hydrochloride | 10122-45-9 | 98.09% | 573.97 | 25 MG
ZZW-115 hydrochloride is a potent NUPR1 inhibitor with a Kd of 2.1 μM. It induces tumor cell death through necroptosis and apoptosis, demonstrating anticancer activity.
- Effective in killing cancer cells with IC50 values ranging from 0.84 μM to 4.93 μM in various cell lines in vitro.
- Induces pancreatic cell death by necrosis and apoptosis, leading to decreased ATP production and increased ROS overproduction.
- Causes higher LDH release and greater caspase 3/7 activity in a concentration-dependent manner.
- Inhibits the growth of pancreatic xenografted tumors in mice when administered at 0.5-5 mg/kg daily for 30 days via injection.
- Dosage of 5 mg/kg for 30 days resulted in almost unmeasurable tumor sizes in some cases of C57BL/6 mice.
- Caused tumors to progressively decrease and almost disappear by the end of treatment in nude mice xenografted with MiaPaCa-2 cells at a 5 mg/kg dose.
Cambridge Isotope Laboratories 4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
Medchemexpress LLC BN82002 hydrochloride | 1049740-43-3 | 99.4% | 395.88 | 25 MG
BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively. It demonstrates approximately 20-fold greater selectivity over CD45 tyrosine phosphatase. It is intended for research use only and is not sold to patients.
- Potent, selective, and irreversible inhibitor of CDC25 phosphatase family.
- Inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat at micromolar concentrations.
- Displays ~20-fold greater selectivity over CD45 tyrosine phosphatase.
- Shown to inhibit cell proliferation in several human tumor cell lines in vitro in a concentration-dependent manner.
- Causes cell cycle arrest at various stages.