Aminophenols
eMolecules 74283-34-4 | 2,4-Diaminophenol sulfate | MFCD01321156 | 1g
Combi-Blocks, Inc. | 2,4-Diaminophenol sulfate | 1g | 603144863 | QC-1959 | 98.000 | 74283-34-4 | MFCD01321156 | 222.220 | C6H10N2O5S
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Medchemexpress LLC Axc-715 hydrochloride | 2490497-93-1 | 99.5% | C18H26ClN5 | 10MG
AXC-715 hydrochloride is the hydrochloride salt of a small-molecule TLR7/TLR8 dual agonist used for preclinical immunology and oncology research. Supplied for research use only, it is described as an immune adjuvant and has been used in synthesis of antibody-adjuvant conjugates and in vivo antitumor models.
- Dual TLR7/TLR8 agonist activity for immune-modulating studies
- High purity (99.5%) for reproducible experimental results
- Hydrochloride salt form improves aqueous solubility relative to the free base
- Suitable for conjugation and formulation in antibody-adjuvant constructs
- Available in small-scale research quantities for preclinical work
- Storage recommendations provided for solid and solution forms to maintain stability
Medchemexpress LLC Tas4464 (hydrochloride) | 1848959-11-4 | 98.9% | 25 MG
TAS4464 hydrochloride is a long-acting, highly selective covalent inhibitor targeting NEDD8-activating enzyme (NAE) with an IC50 of 0.955 nM. It exhibits antiproliferative and cytotoxic effects with broad-spectrum antitumor activity against various hematologic and solid tumor cell lines and patient-derived tumor cells. This compound has a wide therapeutic window without obvious toxicity and is suitable for research in hematologic malignancies and solid tumors.
- Highly potent and selective NAE inhibitor
- Demonstrates broad-spectrum antitumor activity against various cancer models
- Induces tumor cell apoptosis
- Increases protein expression levels of CRL ubiquitin ligase substrates
- Inhibits migratory capacity of solid tumor cell lines
- Achieves complete tumor regression in various animal models
- Prolongs survival and reduces tumor burden in lymphoma models
- Possesses a wide therapeutic window without obvious toxicity
eMolecules 258331-10-1 | TERT-BUTYL 2-(2-HYDROXYPHENYL)ACETATE | AstaTech | MFCD25019077 | 208.257 | C12H16O3 | 95.000 | CC(C)(C)OC(=O)Cc1ccccc1O | 1g | 335884869
TERT-BUTYL 2-(2-HYDROXYPHENYL)ACETATE | AstaTech | 258331-10-1 | MFCD25019077 | 208.257 | C12H16O3 | 95.000 | CC(C)(C)OC(=O)Cc1ccccc1O | 1g | 335884869
Medchemexpress LLC Acetaminophen glucuronide-d3 sodium salt | 1260619-61-1 | 97.8% | 352.29 g/mol | C14H13D3NNaO8 | 2.5 MG
Acetaminophen glucuronide-d3 sodium salt is the deuterium-labeled sodium salt of acetaminophen glucuronide, supplied as a stable isotope standard for analytical and metabolic research. It is intended as a reference material for quantitative mass spectrometry and chromatographic assays to improve accuracy and traceability in metabolite measurement.
- Deuterium-labeled sodium salt suitable as an internal standard.
- Enables accurate MS and LC quantitation of acetaminophen metabolites.
- Molecular formula C14H13D3NNaO8; molecular weight 352.29 g/mol.
- Provided in a research-grade, solid form for laboratory use.
- For research use only; not for human or clinical use.
Medchemexpress LLC OTs-C6-OBn | 126519-80-0 | 98.1% | 500 MG
OTs-C6-OBn is an alkyl chain-based PROTAC linker utilized in the synthesis of PROTAC SGK3 degrader-1 (HY-125878). PROTACs, or Proteolysis Targeting Chimeras, consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to a target protein. These molecules function by exploiting the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTAC SGK3 degrader-1
- PROTACs utilize the ubiquitin-proteasome system for selective protein degradation
eMolecules 1448584-12-0 | Medchem Express | S55746 | 5mg | 446260465 | HY-117288 | 710.831 | C43H42N4O6
Ambeed | (R)-2-(6-Methylpyridin-2-yl)-4-phenyl-45-dihydrooxazole | 100mg | 649269024 | A1476160 | 199277-73-1 | 238.290 | C15H14N2O
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Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 50 MG
Hypidone hydrochloride (YL0919) is a research-stage small molecule characterized as a 5-HT (serotonin) receptor agonist. Supplied as the hydrochloride salt, it is intended for in vitro neuroscience and pharmacology research and is provided with supporting analytical documentation.
- Characterized as a 5-HT receptor agonist for neuroscience research.
- Supplied as the hydrochloride salt suitable for laboratory use.
- High purity (99.7%) as reported by the manufacturer.
- Available in small-mass formats and as a 10 mM solution in DMSO.
- Provided with datasheet, SDS, COA, and LCMS documentation.
Medchemexpress LLC Nefopam (hydrochloride) | 23327-57-3 | 99.9% | 100 MG
Nefopam hydrochloride is a centrally-acting, non-opioid, and non-steroidal analgesic drug. It is derived from benzoxazocine and is used for the relief of moderate to severe pain. It targets β-catenin protein levels in mesenchymal cells both in-vitro and in-vivo, inhibiting β-catenin mediated signaling during skin wound repair.
- Centrally-acting analgesic
- Non-opioid and non-steroidal properties
- Aids in the relief of moderate to severe pain
- Inhibits β-catenin mediated signaling
- Derived from benzoxazocine
Medchemexpress LLC Daurk-4 hydrochloride | 00-00-0 | 99.4% | C52H53Cl2FN8O12 | 10MG
dAURK-4 hydrochloride is a PROTAC derivative designed to selectively degrade Aurora A kinase (AURKA). It is supplied as a hydrochloride salt for research use in oncology and cell-cycle investigations, offering high purity and validated storage recommendations for small-scale laboratory studies.
- Potent and selective degrader of Aurora A kinase.
- High chemical purity suitable for research applications.
- Available as a hydrochloride salt for improved handling.
- Supplied in small quantities appropriate for in vitro studies.
- Detailed storage guidance provided to preserve stability.
eMolecules 1448525-91-4 | Medchem Express | S55746 (hydrochloride) | 5mg | 482204184 | HY-117288A | 747.29 | C43H43ClN4O6
Ambeed | (S)-4-Isopropyl-2-(6-methylpyridin-2-yl)-45-dihydrooxazole | 250mg | 649269036 | A1476164 | 199277-70-8 | 204.273 | C12H16N2O
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![Medchemexpress LLC N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide | 1259484-97-3 | 99.3% | 394.42 g/mol | C21H22N4O4 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000262954.png-250.jpg)
Medchemexpress LLC N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide | 1259484-97-3 | 99.3% | 394.42 g/mol | C21H22N4O4 | 5 MG
SKI-178 is a small-molecule inhibitor of sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2) that induces apoptosis in various cancer cell lines. It is provided as a high-purity research reagent for in vitro studies, with reported cytotoxic activity in the low micromolar range.
- Potent SphK1 and SphK2 inhibition
- Cytotoxic in cancer cell lines at low micromolar concentrations
- High purity suitable for research applications
- Available in multiple package sizes for screening and follow-up studies
- Molecular weight 394.42 and formula C21H22N4O4
eMolecules 1965305-06-9 | 2-(2-Tolyl)-4-(2-hydroxyphenyl)thiazole | Oakwood Chemical | MFCD28166216 | 267.350 | C16H13NOS | 97.000 | Cc1ccccc1-c1nc(cs1)-c1ccccc1O | 1g | 537706224
2-(2-Tolyl)-4-(2-hydroxyphenyl)thiazole | Oakwood Chemical | 1965305-06-9 | MFCD28166216 | 267.350 | C16H13NOS | 97.000 | Cc1ccccc1-c1nc(cs1)-c1ccccc1O | 1g | 537706224
![Medchemexpress LLC 5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-7-methyl (7aR) | 548-08-3 | 99.9% | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232094.png-250.jpg)
Medchemexpress LLC 5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-7-methyl (7aR) | 548-08-3 | 99.9% | 10 MG
Roemerine is an aporphine alkaloid small-molecule reagent used in biochemical and pharmacological research. It is supplied in small-mass packs for in vitro studies and is commonly used to probe P-glycoprotein interactions and serotonin receptor activity.
- High purity suitable for analytical and biological assays.
- Available in small pack sizes, including 10 MG.
- Molecular weight 279.33 g/mol and formula C18H17NO2 for reference.
- Store sealed at 4°C; follow low-temperature storage guidelines for solutions.
Ambeed 2 1HImidazol4yl ethan1amine di
2-(1H-Imidazol-4-yl)ethan-1-amine dihydrochloride, 56-92-8, 98%