Aminophenols
Medchemexpress LLC AFM-30a (hydrochloride) | 99.8% | 502.97 | 25 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. It can be used for the research of certain cancers and various autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.
- Potent protein arginine deiminase 2 (PAD2) inhibitor
- Excellent PAD2-selectivity
- Inhibits H3 citrullination
- Low cytotoxicity for cells
- Suppresses NLRP3 signaling and decreases airway remodeling in PAD2-/-transgenic mice
- For research use only
eMolecules 3,6-Dimethyl-2-nitrophenol | 71608-10-1 | MFCD12198862 | 1g
Combi-Blocks | 3,6-Dimethyl-2-nitrophenol | 1g | 517034738 | ST-4209 | 95.000 | 71608-10-1 | MFCD12198862 | 167.164 | C8H9NO3
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eMolecules 2-Amino-6-nitrophenol | 603-87-2 | MFCD02751769 | 1g
Combi-Blocks | 2-Amino-6-nitrophenol | 1g | 439369036 | QB-1798 | 95.000 | 603-87-2 | MFCD02751769 | 154.125 | C6H6N2O3
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Medchemexpress LLC UNC2025 hydrochloride | 2070015-17-5 | MFCD28963885 | 100.0% | 513.12 g/mol | C28H41ClN6O | 100MG
UNC2025 hydrochloride is an ATP-competitive, orally active inhibitor of Mer and FLT3 kinases used in preclinical leukemia research and kinase signaling studies. It demonstrates potent inhibition, selectivity for MERTK, and stability suitable for laboratory workflows.
- Sub-nanomolar potency against Mer and FLT3.
- Greater than 45-fold selectivity for MERTK versus Axl.
- High purity solid form suitable for biochemical and cellular assays.
- Available in multiple quantities including 100 mg for in vivo or dosing studies.
- Stable when stored sealed at 4°C; in solution store at -80°C for long term.
Cell Signaling Technology 5-Carboxylcytosine (5-caC) (D7S8U) Rabbit mAb 20 ul
5-Carboxylcytosine (5-caC) (D7S8U) Rabbit mAb 20 ul
Medchemexpress LLC GSK 690 Hydrochlorid 10mM 1mL | 2436760-79-9 | 405.92 | C24H24ClN3O | 1 ML
GSK 690 Hydrochloride is a reversible inhibitor of lysine-specific demethylase 1 (LSD1) with reported Kd 9 nM and biochemical IC50 37 nM. It is supplied for research use in solution and solid formats and is characterized by high purity suitable for biochemical assays.
- Reversible LSD1 inhibitor with Kd 9 nM and IC50 37 nM.
- Supplied as 10 mM solution in DMSO (1 mL) and as solid quantities.
- High purity (98.58%) suitable for biochemical and cell-based studies.
- Molecular weight 405.92 and formula C24H24ClN3O.
- Storage: sealed at 4°C; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC L-NAME (hydrochloride) | 51298-62-5 | 99.9% | 269.69 | 5 G
L-NAME hydrochloride is an inhibitor of nitric oxide synthase (NOS) with an IC50 of 70 μM. It acts as a precursor to the NOS inhibitor L-NOARG, which has an IC50 value of 1.4 μM. It is used for research purposes only and is not sold to patients.
- Inhibits NOS with an IC50 of 70 μM.
- Precursor to the more potent NOS inhibitor L-NOARG (IC50 = 1.4 μM).
- Can be used to induce hypertension models in animals.
- Can be used to induce preeclampsia models in animals.
Medchemexpress LLC Dimedone (5,5-dimethylcyclohexane-1,3-dione) | 126-81-8 | MFCD00001588 | 99.7% | 140.18 g/mol | C8H12O2 | 1000 G
Dimedone (5,5-dimethylcyclohexane-1,3-dione) is a small-molecule biochemical reagent used in laboratory research. It is a cyclic diketone (CAS 126-81-8) with formula C8H12O2 and molecular weight 140.18 g/mol. The material is supplied for research use only and is provided at high stated purity.
- High purity (99.7%).
- CAS number 126-81-8.
- Chemical formula C8H12O2.
- Molecular weight 140.18 g/mol.
- Soluble in DMSO.
- Available in multiple bulk pack sizes for laboratory use.
Medchemexpress LLC Abaucin hydrochloride | 1173022-16-6 | >98% | 426.86 | 1 ML
Abaucin hydrochloride is a potent CCR2 antagonist (IC50: 360 nM) with no effect on CCR1, primarily used in neurological disease and endocrinology research. It targets human α1a, α1d receptors, and rat brain cortex 5HT1a receptor, and suppresses wild type and D284N mutant MCP-1 receptor activity. In vivo studies show it decreases pain thresholds in rats with bone cancer pain.
- Potent CCR2 antagonist (IC50: 360 nM), no effect on CCR1
- Inhibits α1a, α1d, and 5HT1a receptors
- Suppresses wild type and D284N mutant MCP-1 receptor
- Reduces extracellular matrix protein expression
- Blocks fibronectin and type IV collagen expression in high glucose-stimulated mesangial cells
- Abrogates increased TGF-1 levels in mesangial cells
- Decreases pain threshold in rats with bone cancer pain
- Reverses NR2B, nNOS, and SIGIRR expression in spinal cord
- Used in neurological disease and endocrinology research
eMolecules Medchem Express / BN82002 (hydrochloride) / 5mg / 694124885 / HY-112776A / / 1049740-43-3 / MFCD08276984 / 395.880 / C19H26ClN3O4
Medchem Express / BN82002 (hydrochloride) / 5mg / 694124885 / HY-112776A / / 1049740-43-3 / MFCD08276984 / 395.880 / C19H26ClN3O4
Medchemexpress LLC Chromotropic acid disodium salt dihydrate | 5808-22-0 | MFCD00150612 | 400.29 g/mol | C10H6Na2O8S2·2H2O | 100G
Chromotropic acid disodium salt dihydrate is the disodium salt form of chromotropic acid used as a chromogenic reagent for qualitative and quantitative detection of formaldehyde. It is supplied as a solid reagent (chemical formula C10H6Na2O8S2·2H2O; molecular weight 400.29 g/mol) for analytical and reagent-preparation applications.
- Used for colorimetric detection of formaldehyde.
- Solid reagent suitable for reagent preparation and analytical assays.
- Molecular weight 400.29 g/mol; chemical formula C10H6Na2O8S2·2H2O.
- Available in common laboratory pack sizes, including 100 g.
- Store dry and cool; in solution, store at -80°C for long-term or -20°C for shorter-term storage.