Aminophenols
eMolecules 2573217-07-7 | 5,5'-(Perfluoropropane-2,2-diyl)bis(2-(allyloxy)aniline) | Apollo Scientific446.393 | C21H20F6N2O2 | 95.000 | Nc1cc(ccc1OCC=C)C(c1ccc(OCC=C)c(N)c1)(C(F)(F)F)C(F)(F)F | 1g | 573019509
5,5'-(Perfluoropropane-2,2-diyl)bis(2-(allyloxy)aniline) | Apollo Scientific | 2573217-07-7446.393 | C21H20F6N2O2 | 95.000 | Nc1cc(ccc1OCC=C)C(c1ccc(OCC=C)c(N)c1)(C(F)(F)F)C(F)(F)F | 1g | 573019509
Medchemexpress LLC CP94253 hydrochloride | 845861-39-4 | MFCD03453293 | 98.8% | 293.79 g·mol⁻¹ | C15H20ClN3O | 1 ML
CP94253 hydrochloride is a potent, selective serotonin 5-HT1B receptor agonist supplied for research use and commonly provided as a 10 mM solution in DMSO for in vitro and in vivo studies.
- Potent 5-HT1B agonist (Ki ≈ 2 nM).
- High purity (≈98.8%).
- Supplied as a 10 mM, 1 mL solution in DMSO; also available as solid in multiple milligram quantities.
- Chemical formula C15H20ClN3O; molecular weight 293.79 g·mol⁻¹.
- Light yellow solid appearance; store sealed and away from moisture; in solvent: -80°C (up to 6 months) or -20°C (1 month).
Medchemexpress LLC CGP71683 hydrochloride | 192322-50-2 | MFCD07783999 | 99.4% | 512.07 | C26H30ClN5O2S | 10 MG
CGP71683 hydrochloride is the hydrochloride salt of a selective neuropeptide Y Y5 receptor antagonist used as a research tool in neuroscience and endocrinology. It is supplied as a high-purity solid for non-clinical laboratory use, with supporting datasheet and certificate of analysis available.
- Selective antagonist for the neuropeptide Y Y5 receptor (Ki ~1.3 nM).
- High reported purity, 99.4%.
- Molecular weight 512.07 g/mol; chemical formula C26H30ClN5O2S.
- CAS number 192322-50-2 for unambiguous identification.
- Solid powder suitable for dissolution in appropriate solvents for assays.
- Supplied with datasheet and certificate of analysis for quality assurance.
- Available in small milligram pack sizes for screening and mechanistic studies.
Medchemexpress LLC OATD-02 hydrochloride | 2146132-73-0 | 99.9% | 308.61 g/mol | C12H26BClN2O4 | 10 MG
OATD-02 hydrochloride is the hydrochloride salt form of an orally active, competitive, reversible, noncovalent dual inhibitor of arginase 1 and arginase 2, intended for preclinical cancer research. It is supplied as a high-purity, water-soluble solid suitable for in vitro and in vivo studies.
- High purity: 99.9%.
- White to off-white solid physical form.
- High aqueous solubility: 250 mg/mL in water (may require ultrasonic).
- Dual arginase 1 and 2 inhibitory activity for tumor immunology research.
- Available in small research pack sizes for preclinical use.
![eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 6mg | 564356415](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000127359.jpg-250.jpg)
eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 6mg | 564356415
Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 6mg | 564356415
Medchemexpress LLC Daurk-4 (hydrochloride) | 99.44% | 1071.93 | 25 MG
dAURK-4 hydrochloride, an Alisertib derivative, is a potent and selective PROTAC AURKA (Aurora A) degrader with anticancer effects. It is composed of a ligand for the target protein, a linker, and a ligand for E3 ligase Thalidomide-O-COOH.
- Potent and selective PROTAC AURKA degrader
- Demonstrates dose-dependent degradation of AURKA
- Inhibits protein level of AURKA in MM.1S cells
- Composed of a ligand for the target protein, a linker, and a ligand for E3 ligase
Medchemexpress LLC Biotin-4-aminophenol | 901770-40-9 | 99.45% | C16H21N3O3S | 100 MG
Biotin-4-aminophenol is a biotin-phenol analog that generates free radicals. It conjugates to tyrosine residues in proteins more efficiently and selectively than the previously reported BP1.
- Biotin-phenol analog
- Generates free radicals
- Efficiently conjugates to tyrosine residues in proteins
- More selective than BP1
- Molecular weight: 335.42
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC AT7519 Hydrochloride | 902135-91-5 | 99.2% | C16H18Cl3N5O2 | 100 MG
AT7519 Hydrochloride is a potent inhibitor of Cyclin-Dependent Kinases (CDKs), exhibiting strong inhibitory activity against CDK1, CDK2, CDK4 to CDK6, and CDK9. It induces dose-dependent cytotoxicity and apoptosis in MM cells and inhibits cell cycle progression in various human tumor cell lines. In preclinical studies, AT7519 Hydrochloride effectively inhibits tumor growth in both human MM and HCT116 xenograft mouse models.
- Potent inhibitor of CDKs (IC50 values range from <10 nM to 210 nM)
- Induces cytotoxicity and apoptosis in MM cells
- Overcomes cytokine and BMSC protective effects
- Inhibits RNA polymerase II CTD phosphorylation and RNA synthesis
- Inhibits cell cycle progression and induces apoptosis in tumor cell lines
- Reduces antiapoptotic protein levels
- Inhibits tumor growth in MM and HCT116 xenograft models
Medchemexpress LLC Nefopam (hydrochloride) | 23327-57-3 | 99.9% | 500 MG
Nefopam hydrochloride is a centrally-acting, non-opioid analgesic drug used for the relief of moderate to severe pain. It also targets β-catenin protein levels in mesenchymal cells both in-vitro and in-vivo.
- Functions as a pain reliever for moderate to severe pain.
- Is a non-opioid drug.
- Targets β-catenin protein levels in mesenchymal cells.
Medchemexpress LLC AT7519 Hydrochloride | 902135-91-5 | 98.6% | C16H18Cl3N5O2 | 25 MG
AT7519 Hydrochloride is a potent inhibitor of CDKs, with IC50s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. It is for research use only.
- Potent inhibitor of CDKs.
- Induces dose-dependent cytotoxicity and apoptosis in multiple myeloma cells.
- Inhibits cell cycle progression and induces apoptosis in human tumor cell lines.
- Inhibits transcription and RNA polymerase II in leukemia cell lines.
- Inhibits tumor growth in human xenograft mouse models.
- Investigated in clinical trials for various cancers.
Medchemexpress LLC Lavendustin B | 125697-91-8 | 98.0% | 365.38 | 500 MG
Lavendustin B is an inhibitor of HIV-1 integrase interaction with LEDGF/p75 with an IC50 of 94.07 μM. It also acts as an ATP-competitive GLUT1 inhibitor with a Ki of 15 μM, and a weak inhibitor of tyrosine kinases.
- Purity: 98.02%
- Appearance: Solid
- Color: White to yellow
- In vitro solubility: 50 mg/mL (136.84 mM)
- Shipping: Room temperature (continental US)
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Thiethylperazine dimaleate | 1179-69-7 | 100.0% | 1 ML
Thiethylperazine dimaleate is a phenothiazine derivative that acts as an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. It is also a selective ABCC1 activator that reduces amyloid-β (Aβ) load in mice. This compound exhibits anti-emetic, antipsychotic, and antimicrobial effects.
- Phenothiazine derivative
- Orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist
- Selective ABCC1 activator
- Reduces amyloid-β (Aβ) load in mice
- Exhibits anti-emetic, antipsychotic, and antimicrobial effects
Medchemexpress LLC Biotin-4-aminophenol | 901770-40-9 | 99.45% | C16H21N3O3S | 25 MG
Biotin-4-aminophenol is a biotin-phenol analog. It is designed for research use only and generates free radicals that conjugate to tyrosine residues in proteins more efficiently and selectively than previously reported BP1. This product is suitable for various laboratory applications.
- Generates free radicals
- Efficiently conjugates to tyrosine residues in proteins
- More selective than BP1
- For research use only
- White to off-white solid appearance