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Filtered Search Results
eMolecules 103-90-2 | Acetaminophen | Combi-Blocks | MFCD00002328 | 151.165 | C8H9NO2 | 98.000 | CC(=O)Nc1ccc(O)cc1 | 100g | 290693474
Acetaminophen | Combi-Blocks | 103-90-2 | MFCD00002328 | 151.165 | C8H9NO2 | 98.000 | CC(=O)Nc1ccc(O)cc1 | 100g | 290693474
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Medchemexpress LLC CGP71683 hydrochloride | 192322-50-2 | MFCD07783999 | 99.4% | 512.07 g/mol | C26H30ClN5O2S | 1 ML
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CGP71683 hydrochloride is a selective, non-peptide neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.3 nM) commonly used in receptor pharmacology and signaling research. It demonstrates substantially reduced activity at Y1 and Y2 receptors and is supplied both as a solid and as a pre-made DMSO solution for ready-to-use assays.
- Selective NPY Y5 receptor antagonist (Ki = 1.3 nM).
- High selectivity over Y1 and Y2 receptors.
- Available as solid or 10 mM solution in DMSO, 1 mL.
- High purity suitable for research applications.
- Intended for receptor pharmacology and signaling studies.
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5000744620 DC-CHOL HYDROCHLORI 25MG
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Medchemexpress LLC dAURK-4 (hydrochloride) | 99.4% | 1071.93 | 100 MG
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dAURK-4 hydrochloride is a potent and selective PROTAC AURKA (Aurora A) degrader. This derivative of Alisertib exhibits anticancer effects and is composed of a ligand for target protein, a linker, and a ligand for E3 ligase.
- Potent and selective degrader of AURKA (Aurora A)
- Exhibits anticancer effects
- Degrades AURKA in a dose-dependent manner (125-1000 nM; 4-24 hours)
- Inhibits protein level of AURKA (Aurora A) in MM.1S cells
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eMolecules 14452-34-7 | 2,4-Dimethyl-6-nitrophenol | MFCD00191633 | 1g
Ambeed | 2-(4-(Trifluoromethoxy)phenyl)ethanol | 1g | 525055889 | A145273 | 196811-90-2 | MFCD08276850 | 206.164 | C9H9F3O2
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Matrix Scientific 1-(4-HYDROXYPHENYL)PIPERAZI-10
1-(4-hydroxyphenyl)piperazine Mf C10h14n2o Mw 178.24 Cas 56621-48-8 Mdl MFCD00066156
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Medchemexpress LLC CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 100 MG
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CSRM617 hydrochloride is the hydrochloride salt of a selective small-molecule inhibitor of the transcription factor ONECUT2, supplied as a white to off-white solid for research use.
- Selective inhibitor of ONECUT2 transcription factor.
- Hydrochloride salt, white to off-white solid.
- Purity 99.97%.
- Molecular weight 291.69 g/mol.
- Soluble in DMSO (100 mg/mL; ultrasonic assistance recommended).
- Store sealed, away from moisture; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for human use.
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Medchemexpress LLC BI-9627 hydrochloride | 1422252-46-7 | 98.0% | 392.80 | 25 MG
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BI-9627 hydrochloride is a potent and selective sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor, with IC50 values of 6 nM and 31 nM. It demonstrates high selectivity over other NHE isoforms and has shown effects on autophagy, pH regulation, and Ca2+ recovery in various cell types. This compound exhibits favorable pharmacokinetic properties and cardioprotective activity. For research use only.
- Potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor (IC50 = 6 and 31 nM).
- High selectivity (>30-fold) against NHE2; no activity against NHE3.
- Decreases autophagy in HTR-8/SVneo cells.
- Reduces pHi of human sperm and partially reverses DMA effect.
- Prolongs Ca2+ recovery time in KO hiPSC-CMs.
- Low drug-drug interaction (DDI) potential.
- Excellent pharmacokinetics in rat and dog.
- Potent activity in isolated heart model of ischemia-reperfusion injury.
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Medchemexpress LLC DC-Chol hydrochloride | 166023-21-8 | >99.9% | 537.26 | 250 MG
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DC-Chol hydrochloride is a cationic lipid that inhibits Aβ40 fibril formation and amyloidogenesis of oxidized hCT. It enhances the body's immune response to antigens by inducing the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. This compound is also utilized as a gene delivery vector.
- Can inhibit Aβ40 fibril formation
- Strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner
- Induces production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines
- Enhances the body's immune response to antigens
- Used as a gene delivery vector
- Can be used in research for hepatitis B vaccines to improve vaccine immunity
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Medchemexpress LLC Biotin-4-aminophenol | 901770-40-9 | 99.45% | C16H21N3O3S | 25 MG
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Biotin-4-aminophenol is a biotin-phenol analog. It is designed for research use only and generates free radicals that conjugate to tyrosine residues in proteins more efficiently and selectively than previously reported BP1. This product is suitable for various laboratory applications.
- Generates free radicals
- Efficiently conjugates to tyrosine residues in proteins
- More selective than BP1
- For research use only
- White to off-white solid appearance
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Medchemexpress LLC SAR7334 hydrochloride | 1333207-63-8 | 98.0% | 440.79 g/mol | C21H24Cl3N3O | 10 MG
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SAR7334 hydrochloride is the hydrochloride salt of SAR7334, a potent and selective small-molecule inhibitor of the TRPC6 ion channel. It inhibits TRPC6 currents with an IC50 of 7.9 nM and is supplied as a high-purity research reagent for biochemical and cellular studies.
- Potent TRPC6 inhibitor (IC50 7.9 nM).
- Hydrochloride salt form for improved stability and solubility.
- Purity: 98.0% (as supplied).
- Molecular weight: 440.79 g/mol.
- Available as milligram quantities and as a 10 mM solution in DMSO.
- Intended for research use only; not for human or clinical use.
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Medchemexpress LLC Acetaminophen | 103-90-2 | 99.97% | C8H9NO2 | 10 G
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Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor and a widely used antipyretic and analgesic agent. It is also a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor that induces ferroptosis and can lead to acute liver injury in mice models.
- Selective COX-2 inhibitor with an IC50 of 25.8 μM
- Widely used as an antipyretic and analgesic
- Potent hepatic N-acetyltransferase 2 (NAT2) inhibitor
- Induces ferroptosis
- Can lead to acute liver injury in mice models
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Medchemexpress LLC Imiloxan hydrochloride | 81167-22-8 | MFCD01074788 | >98.0% | 280.75 | C14H17ClN2O2 | 25 MG
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Imiloxan hydrochloride is the hydrochloride salt of imiloxan, a potent and selective α2B-adrenoceptor antagonist used in pharmacology research. Supplied as a solid reagent, it is intended for distinguishing α2 receptor subtypes and for probing adrenergic signaling in both in vitro and in vivo studies.
- Potent, selective α2B-adrenoceptor antagonist for receptor pharmacology.
- Suitable for both in vitro and in vivo pharmacodynamic studies.
- High purity (≥98% HPLC) supporting reproducible results.
- Hydrochloride salt form improves aqueous solubility for dosing.
- Available in small research pack sizes appropriate for screening and dosing.
- Molecular formula C14H17ClN2O2; molecular weight 280.75 g/mol.
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Medchemexpress LLC UNC9994 hydrochloride | 2108826-33-9 | 99.5% | 457.84 | 25 MG
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UNC9994 hydrochloride is a functionally selective, β-arrestin-biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. It exhibits a binding affinity with a Ki of 79 nM for D2R. This compound also acts as an antagonist of Gi-regulated cAMP production and a partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride demonstrates antipsychotic-like activity. For research use only.
- Selectively activates β-arrestin recruitment and signaling
- Exhibits binding affinity with a Ki of 79 nM for D2R
- Acts as an antagonist of Gi-regulated cAMP production
- Functions as a partial agonist for D2R/β-arrestin-2 interactions
- Demonstrates antipsychotic-like activity
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Medchemexpress LLC NPS-2143 hydrochloride | 324523-20-8 | MFCD16038896; MFCD04113010 | 100.0% | 445.38 g/mol | C24H26Cl2N2O2 | 50 MG
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NPS-2143 hydrochloride is an orally active calcilytic small molecule that selectively antagonizes the calcium-sensing receptor (CaSR), inhibiting CaSR-mediated increases in intracellular Ca2+. It is supplied as a solid at high purity for use in biochemical and pharmacological research into CaSR signaling and related physiological pathways.
- Selective CaSR antagonist for CaSR signaling studies.
- Orally active calcilytic small molecule suitable for in vitro and in vivo research.
- High purity solid appropriate for research applications.
- Molecular weight 445.38 g/mol and chemical formula C24H26Cl2N2O2.
- Available in small research quantities, including 50 MG.
- Applicable to biochemical, cellular, and pharmacological assays.
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