Aminophenols
Cayman Chemical N-formyl-2-AmInophenol 100mg
A bacterial secondary metabolite with antioxidant activity; scavenges DPPH radicals in a cell-free assay (IC50 = 3.23 UG/ml); has been used in the synthesis of compounds with antibacterial and antifungal activities
Medchemexpress LLC MRL-494 (hydrochloride) | 2699937-04-5 | 98.6% | 25 MG
MRL-494 hydrochloride is an antibacterial agent that acts as an inhibitor of β-barrel assembly machine A (BamA). It is impervious to efflux and the outer membrane permeability barrier, effectively inhibiting both Gram-positive and Gram-negative bacteria. The agent lethally disrupts the cytoplasmic membrane and inhibits outer membrane protein biogenesis by targeting BamA.
- Impervious to efflux and outer membrane permeability barrier
- Inhibits both Gram-positive and Gram-negative bacteria
- Lethally disrupts cytoplasmic membrane
- Inhibits outer membrane protein biogenesis
Medchemexpress LLC Cal-130 hydrochloride | 1431697-78-7 | 98.7% | 462.93 g/mol | C23H23ClN8O | 10 MG
Cal-130 hydrochloride is the hydrochloride salt of a small-molecule inhibitor selective for PI3Kδ (p110δ) and PI3Kγ (p110γ). It is supplied as a solid research reagent and shows low-nanomolar potency against its primary targets, with weaker activity toward other PI3K isoforms.
- Selective inhibition of PI3Kδ and PI3Kγ, low-nanomolar IC50 values
- Demonstrates activity against additional PI3K isoforms at higher concentrations
- High chemical purity suitable for in vitro and preclinical research
- Supplied as a solid, with common pack sizes suitable for laboratory studies
- Provided with documentation that includes molecular formula, molecular weight, and CAS number
Apexbio Technology LLC MOG (35-55) 149635-73-4 1mg
MOG (35-55) (CAS 149635-73-4) is a truncated peptide derived from human myelin oligodendrocyte glycoprotein (MOG) MOG an immunoglobulin superfamily glycoprotein specifically expressed in the central nervous system serves as a target antigen in experimental autoimmune encephalomyelitis (EAE) an animal model resembling multiple sclerosis (MS) The MOG (35-55) peptide induces strong inflammatory responses via activation of autoreactive T cells and promotion of autoantibody production leading to extensive demyelination Due to its prominent encephalitogenic properties it is widely utilized in preclinical research for studying MS pathogenesis and therapeutic interventions
Medchemexpress LLC G-5555 hydrochloride | 2319590-15-1 | 98.3% | 529.42 | 25 MG
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM. This compound is intended for research use only.
- Potent and selective p21-activated kinase 1 (PAK1) inhibitor.
- Exhibits excellent kinase selectivity.
- Shows low blood clearance and acceptable half-life.
- Offers good oral exposure and high oral bioavailability.
- Demonstrates tumor growth inhibition in xenograft models.
Medchemexpress LLC Quercetagetin-7-O-glucoside | 548-75-4 | MFCD09263523 | 480.38 g/mol | C21H20O13 | 10 MG
Quercetagitrin (quercetagetin-7-O-glucoside) is a naturally occurring flavone glycoside supplied as an analytical standard for research and analytical applications. It has reported anti-inflammatory and neuroprotective activities, inhibits Tau accumulation, and shows activity against protein tyrosine phosphatases (PTPN6, PTPN9). Researchers use it in preclinical studies of neuroinflammation, Alzheimer's disease models, and glucose uptake assays.
- Natural flavone glycoside and analytical standard.
- Reported anti-inflammatory and neuroprotective activity.
- Inhibits Tau accumulation and NF-κB activation in preclinical models.
- Shows inhibitory activity vs PTPN6 and PTPN9 and enhances glucose uptake.
- Intended for research use only; refer to Certificate of Analysis for storage and assay details.
Medchemexpress LLC NS8593 (hydrochloride) | 875755-24-1 | 99.8% | 299.80 | 25 MG
NS8593 hydrochloride is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels). It reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. It also inhibits SK1-3 subtypes in a Ca2+-dependent manner (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), but it does not affect intermediate and large conductance Ca2+-activated K+ channels (hIK and hBK channels).
- Potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor.
- Reversibly inhibits SK3-mediated currents.
- Active on apamin-insensitive SK3 channels.
- Affects firing rate and pattern of dopaminergic neurons in vivo.
Medchemexpress LLC DMT-dI Phosphoramidite | 141684-35-7 | >98.1% | 754.81 | 1 ML
DMT-dI Phosphoramidite is a modified phosphoramidite monomer specifically utilized for oligonucleotide synthesis. It is presented as a solid, appearing in a white to off-white color. The product should be stored at 4°C in a sealed container, away from moisture and light. If stored in solvent, it maintains stability at -80°C for 6 months or at -20°C for 1 month under sealed conditions, also away from moisture and light.
- Appearance: Solid
- Color: White to off-white
- Storage:
- 4°C, sealed storage, away from moisture and light.
- In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture and light).
- Solubility: Soluble in DMSO at 125 mg/mL (165.60 mM), requiring ultrasonication.
eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 9mg | 564356418
Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 9mg | 564356418
TARGETMOL CHEMICALS INC E7016 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo. purity: 98%