Aminophenols
Medchemexpress LLC CX-6258 hydrochloride hydrate | 1353858-99-7 | 99.23% | 516.42 | 100 MG
CX-6258 hydrochloride hydrate is a potent and kinase-selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM, and 16 nM for Pim-1, Pim-2, and Pim-3, respectively. It is intended for research use only and not for sale to patients.
- Potent and kinase selective pan-Pim kinases inhibitor.
- Inhibits the phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites (S112, S65, and T37/46 respectively).
- Diminishes steady-state levels of ectopic NKX3.1 in PC3 cells.
- Reduces NKX3.1 half-life.
- Exhibits robust in vivo efficacy in two Pim kinases driven tumor models, showing dose-dependent tumor growth inhibition (TGI) of 45% at 50 mg/kg and 75% at 100 mg/kg in MV-4-11 xenograft models in nude mice.
eMolecules 103-90-2 | Acetaminophen | Combi-Blocks | MFCD00002328 | 151.165 | C8H9NO2 | 98.000 | CC(=O)Nc1ccc(O)cc1 | 1kg | 335345646
Acetaminophen | Combi-Blocks | 103-90-2 | MFCD00002328 | 151.165 | C8H9NO2 | 98.000 | CC(=O)Nc1ccc(O)cc1 | 1kg | 335345646
Medchemexpress LLC V-0219 hydrochloride | 2922283-73-4 | 99.4% | C20H26ClF3N4O2 | 1 ML
V-0219 hydrochloride is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). This compound is suitable for research related to obesity-associated diabetes.
- Orally active GLP-1R positive allosteric modulator
- Useful for obesity-associated diabetes research
- Purity of 99.39%
- Molecular weight of 446.89
- Chemical formula: C20H26ClF3N4O2
- CAS number: 2922283-73-4
- Appearance: White to off-white solid
- Target: GLP-1R
Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | MFCD09882200 | 99.95% | 372.89 | 50 MG
CBL0137 hydrochloride | 1197397-89-9 | MFCD09882200 | 99.95% | 372.89 | 50 MG
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 1 ML
Hypidone hydrochloride is a research-grade small molecule reported to act as an orally active antidepressant agent with activity at serotonin (5-HT) receptors. It is provided for laboratory research use and is available both as solid quantities and as a ready-to-use solution in DMSO, with supporting product documentation and safety data.
- Research-grade 5-HT receptor agonist for laboratory studies.
- High purity suitable for research (reported 99.73%).
- Available as solids and as a 10 mM, 1 mL solution in DMSO.
- Chemical identifiers: CAS 1339058-04-6; formula C18H23ClN2O2; MW 334.84 g/mol.
- Intended for in vitro and in vivo research; not for human use.
- Supplied with datasheet and safety data sheet for handling and storage.
Medchemexpress LLC R 59-022 (hydrochloride) | 93076-98-3 | MFCD34676749 | 98.9% | 496.04 g/mol | C27H27ClFN3OS | 25 MG
R 59-022 (hydrochloride) is the hydrochloride salt of a small-molecule diacylglycerol kinase inhibitor used for laboratory research. It is provided as an off-white to light yellow solid with molecular formula C27H27ClFN3OS and molecular weight 496.04 g/mol. The compound is reported with high purity and is accompanied by an SDS for safe handling and storage.
- Used as a diacylglycerol kinase inhibitor in biochemical assays.
- High purity (98.9%).
- Molecular weight 496.04 g/mol.
- Formula C27H27ClFN3OS.
- Off-white to light yellow solid appearance for easy visual inspection.
- Supplied in 25 mg research quantities suitable for screening and assay development.
eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET - Building Blocks236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 4mg | 344516857
Medetomidine Hydrochloride | Key Organics/BIONET - Building Blocks | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 4mg | 344516857
Medchemexpress LLC Bepridil hydrochloride | 68099-86-5 | MFCD00065498 | 100.0% | 403.00 g/mol | C24H35ClN2O | 5 MG
Bepridil hydrochloride is the hydrochloride salt of bepridil, a non-selective calcium channel blocker with antianginal activity supplied as a research reagent for in vitro and analytical applications.
- High purity solid (99.98%) suitable for analytical and in vitro research.
- Non-selective calcium channel blocker, useful for cardiovascular and ion-channel studies.
- Available in small analytical pack sizes for assay development and screening.
- Stable when stored sealed and away from moisture; recommended -20°C for long-term storage.
- Also available as a ready-to-use solution (10 mM in DMSO) for assay workflows.
Medchemexpress LLC Mepazine hydrochloride | 2975-36-2 | 99.3% | 5 MG
Mepazine hydrochloride is the hydrochloride salt of mepazine, supplied for research use as a solid or as a DMSO solution and intended for in vitro biochemical and cellular assays.
- High purity (99.25%).
- Molecular formula C19H23ClN2S.
- Molecular weight 346.92 g/mol.
- Available in small solid packs and a 10 mM DMSO solution format.
- Store sealed at 4°C; in solution, store at -80°C for long-term stability.
Medchemexpress LLC BIIL-260 hydrochlori 10mg | 192581-24-1 | 10 MG
Biil-260 hydrochloride is the hydrochloride salt of BIIL-260, a potent, orally active leukotriene B4 (LTB4) receptor antagonist with anti-inflammatory activity. It binds the human LTB4 receptor reversibly and competitively (reported Ki ≈ 1.7 nM) and is supplied as a high-purity solid for research use.
- Potent LTB4 receptor antagonist with reported high affinity (Ki ≈ 1.7 nM).
- High purity solid suitable for in vitro and preclinical research.
- Available in small milligram quantities for compound screening and assay development.
- Soluble in DMSO for preparation of concentrated stock solutions.
Medchemexpress LLC Abaucin hydrochloride | 1173022-16-6 | >98% | 426.86 | 1 ML
Abaucin hydrochloride is a potent CCR2 antagonist (IC50: 360 nM) with no effect on CCR1, primarily used in neurological disease and endocrinology research. It targets human α1a, α1d receptors, and rat brain cortex 5HT1a receptor, and suppresses wild type and D284N mutant MCP-1 receptor activity. In vivo studies show it decreases pain thresholds in rats with bone cancer pain.
- Potent CCR2 antagonist (IC50: 360 nM), no effect on CCR1
- Inhibits α1a, α1d, and 5HT1a receptors
- Suppresses wild type and D284N mutant MCP-1 receptor
- Reduces extracellular matrix protein expression
- Blocks fibronectin and type IV collagen expression in high glucose-stimulated mesangial cells
- Abrogates increased TGF-1 levels in mesangial cells
- Decreases pain threshold in rats with bone cancer pain
- Reverses NR2B, nNOS, and SIGIRR expression in spinal cord
- Used in neurological disease and endocrinology research
Medchemexpress LLC LDC4297 (hydrochloride) | 2319747-14-1 | 98.2% | 25 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7, effectively inhibiting human cytomegalovirus (HCMV) replication. It exhibits broad antiviral activities against various virus families including Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae. This compound is suitable for infection research.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Demonstrates broad antiviral activities against multiple virus families
- Useful for infection research
- Solid form storage: 4°C, sealed, away from moisture and light
- In-solvent storage: -80°C for 6 months or -20°C for 1 month, sealed, away from moisture and light
Aobchem 4-Bromo-N-(2-hydroxy-1 1-dimethylethyl)benzenesulfonamide | 95% | CAS 502484-72-2 | C10H14BrNO3S | 1g
4-Bromo-N-(2-hydroxy-1 1-dimethylethyl)benzenesulfonamide | 95% | CAS 502484-72-2 | C10H14BrNO3S | 1g