Aminophenols
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 1 ML
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This product shows broad antiviral activities against Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. It can be used for infection research.
- Dose-dependently inhibits HCMV replication with an EC50 of 24.5 nM
- Shows anti-proliferative activity in primary human fibroblast cultures with a GI50 of 4.5 μM
- Exhibits anti-HCMV activity by interfering with virus-induced Rb phosphorylation
- Demonstrates broad antiviral activities against various viruses including HCMV, GPCMV, MCMV, HIV-1, and Influenza A virus
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 10 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It demonstrates broad antiviral activities against various viruses, including human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. Its antiviral spectrum extends to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. This compound is suitable for research related to infection.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Shows broad antiviral activities against multiple virus families
- Exhibits anti-proliferative activity against human fibroblast primary cultures
- Interferes with virus-induced Rb phosphorylation
- Demonstrates promising pharmacokinetic properties in CD1 mice
Medchemexpress LLC LDC4297 (hydrochloride) | 2319747-14-1 | 98.2% | 25 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7, effectively inhibiting human cytomegalovirus (HCMV) replication. It exhibits broad antiviral activities against various virus families including Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae. This compound is suitable for infection research.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Demonstrates broad antiviral activities against multiple virus families
- Useful for infection research
- Solid form storage: 4°C, sealed, away from moisture and light
- In-solvent storage: -80°C for 6 months or -20°C for 1 month, sealed, away from moisture and light
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.23% | 100 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This compound demonstrates broad antiviral activities against various viruses, including Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. LDC4297 hydrochloride is suitable for infection research.
- Selective CDK7 inhibitor (IC50: 0.13 nM)
- Inhibits human cytomegalovirus (HCMV) replication (EC50: 24.5 nM)
- Exhibits broad antiviral activities against various viruses (EC50: 0.02-1.21 μM)
- Useful for infection research
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 50 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This compound demonstrates broad antiviral activities against Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. It is suitable for research related to infection.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Broad antiviral activities against various viruses
- Suitable for infection research
- Exhibits anti-proliferative activity in human fibroblasts
- Demonstrates good oral bioavailability and half-life in vivo
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | MFCD34676707 | 98.2% | 468.98 | C23H29ClN8O | 5 MG
LDC4297 hydrochloride is a small-molecule research reagent that selectively inhibits cyclin-dependent kinase 7 (CDK7). Supplied as the hydrochloride salt for laboratory use only, it is intended for cell-signaling and antiviral research and is available in both solid and solution formats.
- Selective CDK7 inhibition for target-specific studies.
- Suitable for in vitro cell-based assays and mechanistic studies.
- Available in multiple sizes including small solid quantities and DMSO solution.
- High purity suitable for research applications.
- Supplied as the hydrochloride salt for improved stability and solubility.
TARGETMOL CHEMICALS INC DBET6 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50 14 nM). It has antitumor activity. purity: 99%
Medchemexpress LLC 3-pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride | 6027-91-4 | MFCD00055191 | 99.9% | 163.60 g/mol | C6H10ClNO2 | 50 MG
Guvacine hydrochloride is the hydrochloride salt of guvacine, a pyridine alkaloid that inhibits GABA transporters. Supplied for research use to study GABA uptake and transporter pharmacology, it has reported activity across cloned human and rat GAT subtypes.
- Inhibits GABA transporter activity; reported IC50s include 14 μM (human GAT-1).
- High purity (≈99.9%) confirmed by COA.
- Molecular weight 163.60 g/mol; molecular formula C6H10ClNO2.
- Available in multiple pack sizes, including 50 mg, and solution formats in DMSO.
- Suitable for biochemical assays and transporter studies.
- Supplied with analytical documentation such as datasheet and COA.