Cresols
BIOHIPPO h/m FGF17-sh-BSD
h/m FGF17-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FGF17 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fibroblast growth factor 17 (FGF17) The shRNA has been validated to meet or exceed 70% knockdown of FGF17 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Cayman Chemical EA4 Fatty Acids and Derivative
An inhibitor of PLA2 from red blood cells (Ki = 130 µM); inhibits the ionophore-induced arachidonic acid release from human and bovine RBCs; induces mRNA expression and increases protein levels of CYP1A1 in murine hepatoma Hepa-1c1c7 cells; modulates CYP1A1 and CYP1B1 expression in MCF-7, Hep-G2, and HL-60 cells
Apexbio Technology LLC EZ Cap Mouse CD252(OX40L) mRNA (m1Ψ HA tag) 5x1mg (1mg/mL)
Mouse CD252 mRNA encodes cytokine OX40 ligand (OX40L) expressed on the surface of activated antigen-presenting cells such as dendritic cells B cells and macrophages Binding to the OX40 receptor (CD134) the CD252-OX40 signaling pathway plays a key role in the immune system promoting T cell proliferation survival and effector functions This signaling pathway significantly influences immune response regulation immune tolerance maintenance and anti-tumor immunity CD252 is involved in the pathological processes of autoimmune diseases and chronic inflammation EZ Cap Mouse CD252 (OX40L) mRNA (m1 HA tag) is provided at 1 mg/mL It expresses mouse-derived CD137 cytokine tagged with HA facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Medchemexpress LLC IHMT-MST1-39 | 2414484-01-6 | 99.68% | 460.46 | 1 ML
IHMT-MST1-39 is an orally active inhibitor for MST kinase. It activates the AMPK signaling pathway in liver cells and reduces apoptosis of pancreatic β-cells, making it suitable for studies related to type 1 and type 2 diabetes.
- Blocks pancreatic β-cell apoptosis through MST1 inhibition
- Enhances pancreatic β-cell function and survival under diabetogenic conditions
- Activates AMPK signaling in HepG2 and HL7702 cells
- Reversed diabetic symptoms in a Streptozotocin (STZ)-induced T1D mouse model
- Prevented diabetic hyperglycemia in T2D mouse models
- Significantly reduced fasting blood glucose and improved glucose tolerance
- Lowered HbA1c levels and protected pancreatic islet structure and beta cell mass
- Improved glycemic control in spontaneous T2D models and HFD/STZ-induced T2D models
- Significantly improved insulin resistance
TARGETMOL CHEMICALS INC RUBUSOSIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Rubusoside is a natural sweetener . 2. Rubusoside is a solubilizing agent with antiangiogenic and antiallergic properties. purity: 99%
TARGETMOL CHEMICALS INC V-9-M Cholecystokinin nonapept
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) is a precursor compound of cholecystokinin (CCK). Cholecystokinin (CCK) is a brain-intestinal peptide that stimulates gallbladder contraction and pancreatic exocrine. It can be extracted from the small intestine of dogs and cats and can cause gallbladder contraction. Purity 98.26%
Cayman Chemical AN7 Fatty Acids and Derivative
A potent antioxidant lipoic acid analog; has 1.5-fold increased maximal capacity over α-lipoic acid to stimulate glucose transport into myocytes
Cambridge Isotope Laboratories 1 2 4 7 9-PentaCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 4 7 9-PentaCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
Medchemexpress LLC Glyoxalase I (GLO1) protein, mouse, His-tagged | 10 UG
Recombinant mouse Glyoxalase I (GLO1) is provided lyophilized with a His tag for use in biochemical assays and enzyme characterization. The protein catalyzes conversion of hemithioacetal to S-D-lactoylglutathione and is supplied with activity and storage recommendations for reliable assay performance.
- Lyophilized recombinant mouse enzyme with His tag.
- Supplied as a 10 μg vial suitable for assay development.
- Specific activity provided to support quantitative enzymatic assays.
- Low endotoxin level to minimize assay interference.
- Stable long term at -20 °C; aliquot after reconstitution to avoid freeze-thaw.
BIOHIPPO h/m SREBP2-sh-GFP-Puro
h/m SREBP2-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m SREBP2 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse sterol regulatory element binding transcription factor 2 (SREBP2/SREBF2) The shRNA has been validated to meet or exceed 70% knockdown of SREBP2 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs