Cresols
TARGETMOL CHEMICALS INC P 22077 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. P 22077 (P22077) is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 uM. It also inhibits the closely related USP47. purity: 98%
Apexbio Technology LLC Ansamitocin P-3 66547-09-9 5mg
Ansamitocin P-3 (CAS 66547-09-9) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly by potently inhibiting tubulin polymerization thereby affecting cellular processes reliant on microtubule dynamics Ansamitocin P-3 exerts its biological activity primarily through inhibition of tubulin polymerization In cell-based studies Ansamitocin P-3 demonstrates cytotoxicity with IC50 values of approximately 4 10 g/ml in human lung carcinoma A-549 and colon carcinoma HT-29 cells and 2 10 g/ml in breast carcinoma MCF-7 cells Additionally it inhibits ciliary regeneration in Tetrahymena cells at concentrations around 1 M Based on these pharmacological properties Ansamitocin P-3 holds research potential in oncology particularly in studies of microtubule dynamics anticancer drug mechanisms and ciliogenesis
Cambridge Isotope Laboratories p-n-Nonylphenol triethoxylate (unlabeled) 100 ug/mL in nonane 1 2 mL
p-n-Nonylphenol triethoxylate (unlabeled) 100 ug/mL in nonane 1 2 mL
Medchemexpress LLC PfLDH P. falciparum 10ug | 10ug
The pfHPRT (Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase) protein is a member of the LDH/MDH (lactate dehydrogenase/malate dehydrogenase) superfamily It plays a crucial role in the purine metabolism salvage pathway of the malaria-causing parasite Plasmodium falciparum PfLDH Protein P falciparum (His) is the recombinant PfLDH protein expressed by E coli with C-His labeled tag
Boston Bioproducts Inc BioAcryl-P Acrylamide/Bis-Acrylamide (40%, 29:1) - 500ml
BioAcryl-P Acrylamide/Bis-Acrylamide (40% 29/1) - 500ml (For Research Use and Further Manufacturing Only)
Medchemexpress LLC Pomalidomide-amido-PEG3-C2-NH2 | 2328070-52-4 | 99.55% | 50 MG
Pomalidomide-amido-PEG3-C2-NH2 is a high-purity, synthesized E3 ligase ligand-linker conjugate designed for research applications in PROTAC technology. This compound incorporates a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. It can be utilized in the synthesis of BI-3663, a compound known to degrade focal adhesion tyrosine kinase (PTK2) in various cell lines.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Features a 3-unit PEG linker
- Used in PROTAC technology
- For research use only
- Can be used to synthesize BI-3663
- Degrades focal adhesion tyrosine kinase (PTK2)
- Purity of 99.55%
- Solid appearance, off-white to light yellow color
Apexbio Technology LLC Ansamitocin P-3 66547-09-9 10mM (in 1mL DMSO)
Ansamitocin P-3 (CAS 66547-09-9) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly by potently inhibiting tubulin polymerization thereby affecting cellular processes reliant on microtubule dynamics Ansamitocin P-3 exerts its biological activity primarily through inhibition of tubulin polymerization In cell-based studies Ansamitocin P-3 demonstrates cytotoxicity with IC50 values of approximately 4 10 g/ml in human lung carcinoma A-549 and colon carcinoma HT-29 cells and 2 10 g/ml in breast carcinoma MCF-7 cells Additionally it inhibits ciliary regeneration in Tetrahymena cells at concentrations around 1 M Based on these pharmacological properties Ansamitocin P-3 holds research potential in oncology particularly in studies of microtubule dynamics anticancer drug mechanisms and ciliogenesis
Medchemexpress LLC p,p'-DDE | 72-55-9 | 99.9% | 1 ML
p,p'-DDE (4,4'-DDE) is a major and persistent metabolite of DDT. It acts as an orally active androgen receptor antagonist with an IC50 of 5 μM and a Ki of 3.5 μM. This compound can impact the development and function of the male reproductive system, and high serum concentrations may contribute to the risk of type 2 diabetes in women.
- Inhibits androgen binding to the androgen receptor.
- Inhibits androgen-induced transcriptional activity.
- Affects male reproductive system development and function.
- May be a risk factor for type 2 diabetes in women due to high serum concentrations.
- Effectively inhibits androgen receptor transcriptional activity at 0.2 μM.
- In vivo studies show effects on anogenital distance, puberty onset, and reproductive organ weights in male rats.
Medchemexpress LLC Tri(2-methylphenyl)phosphine | 6163-58-2 | 99.99% | C21H21P | 25 G
Tri(2-methylphenyl)phosphine is an organic phosphorus ligand that can be used as a drug intermediate to form complexes with metal salts. It is for research use only.
- Organic phosphorus ligand
- Can be used as a drug intermediate
- Forms complexes with metal salts
- White to off-white solid appearance
- For research use only
TARGETMOL CHEMICALS INC AMYLOID P-IN-1 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease amyloidosis osteoarthritis and type 2 diabetes mellitus. purity: 98%
Medchemexpress LLC Heparinase II P. he 500ug | 500ug
Heparinase II protein is an enzyme that cleaves heparin and heparan sulfate glycosaminoglycans using a beta elimination mechanism Specifically it cleaves heparin at the -D-GlcNp2S6S(1- 4) -L-IdoAp2S site and at the -D-GlcNp2Ac(or 2S)6OH(1- 4)beta-D-GlcAp position Site of cleavage of heparan sulfate Heparinase II Protein P heparinus (His) is the recombinant Heparinase II protein expressed by E coli with N-His labeled tag
![eMolecules 91524-96-8 | 2-Chlorothiazolo[5,4-b]pyridine | Ambeed | MFCD13190222 | 170.610 | C6H3ClN2S | 97.000 | Clc1nc2cccnc2s1 | 100mg | 552657396](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000192822.jpg-250.jpg)
eMolecules 91524-96-8 | 2-Chlorothiazolo[5,4-b]pyridine | Ambeed | MFCD13190222 | 170.610 | C6H3ClN2S | 97.000 | Clc1nc2cccnc2s1 | 100mg | 552657396
2-Chlorothiazolo[5,4-b]pyridine | Ambeed | 91524-96-8 | MFCD13190222 | 170.610 | C6H3ClN2S | 97.000 | Clc1nc2cccnc2s1 | 100mg | 552657396
Cayman Chemical 17phenyl trinor13 14dihydro P
17-phenyl trinor-13,14-dihydro PGA2 is a synthetic PG analog whose biological activity has not been widely reported. The PGF2α analog latanoprost, which bears the same lower side chain features, has been approved as a pharmaceutical for the treatment of glaucoma.{5338}
eMolecules 455887-97-5 | 2-(4-Bromo-2,6-dimethylphenoxy)acetic acid | Combi-Blocks, Inc. | MFCD03537971 | 259.099 | C10H11BrO3 | 98.000 | Cc1cc(Br)cc(C)c1OCC(O)=O | 1g | 797028067
2-(4-Bromo-2,6-dimethylphenoxy)acetic acid | Combi-Blocks, Inc. | 455887-97-5 | MFCD03537971 | 259.099 | C10H11BrO3 | 98.000 | Cc1cc(Br)cc(C)c1OCC(O)=O | 1g | 797028067
BIOHIPPO h/m FASN-sh-GFP/Luc
h/m FASN-sh-GFP/Luc shRNA lentiviral vector expressing GFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m FASN shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fatty acid synthase (FASN) The shRNA has been validated to meet or exceed 70% FASN knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs