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Filtered Search Results
Medchemexpress LLC Brombuterol hydroch | 50MG
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Brombuterol hydroch | 50MG
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Medchemexpress LLC Crinecerfont hydrochloride | 321839-75-2 | MFCD05260970 | 98.0% | 519.50 g·mol⁻¹ | C27H29Cl2FN2OS | 50 MG
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Crinecerfont hydrochloride is the hydrochloride salt of crinecerfont (SSR-125543), a selective corticotropin-releasing factor type-1 (CRF1) receptor antagonist supplied as a research reagent for pharmacology and preclinical studies.
- Selective corticotropin-releasing factor type-1 (CRF1) receptor antagonist.
- Intended for pharmacology and biochemical research applications.
- Purity 98.0%.
- Molecular weight 519.50 g·mol⁻¹.
- Molecular formula C27H29Cl2FN2OS.
- Typical packaging 50 mg.
- CAS number 321839-75-2.
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Medchemexpress LLC Metipranolol hydrochloride | 36592-77-5 | 99.9% | 345.86 | 100 MG
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Metipranolol hydrochloride is a non-selective β adrenergic receptor blocking agent. It is used systemically for the treatment of arterial hypertension and topically for the management of glaucoma.
- Non-selective β adrenergic receptor blocking agent
- For research use only
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Medchemexpress LLC Eltoprazine hydrochloride | 98206-09-8 | 99.25% | 256.73 | 1 ML
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Eltoprazine hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. It shows antiaggressive and anxiogenic effects.
- Acts as a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist.
- Shows antiaggressive and anxiogenic effects.
- For research use only.
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Medchemexpress LLC Eltoprazine hydrochloride | 98206-09-8 | 99.3% | 256.73 | 25 MG
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Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. It shows antiaggressive and anxiogenic effects.
- Acts as a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist.
- Shows antiaggressive and anxiogenic effects.
- Purity of 99.25%.
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Medchemexpress LLC Benserazide (hydrochloride) | 14919-77-8 | MFCD00078571 | 99.7% | 1 G
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Benserazide hydrochloride is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. It is also a PKM2 inhibitor that directly binds to and blocks PKM2 enzyme activity, leading to the inhibition of aerobic glycolysis and concurrent up-regulation of OXPHOS. It can be used for the study of Parkinson's disease and melanoma.
- Aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor
- PKM2 inhibitor
- Directly binds to and blocks PKM2 enzyme activity
- Inhibits aerobic glycolysis
- Up-regulates OXPHOS
- Useful for the study of Parkinson's disease and melanoma
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Medchemexpress LLC Bupivacaine hydrochloride | 18010-40-7 | 99.99% | 100 MG
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Bupivacaine hydrochloride is an analytical standard intended for research and analytical applications. It functions as an NMDA receptor inhibitor and can block sodium, L-calcium, and potassium channels, with potent blocking action on SCN5A channels. This compound can be used for research related to chronic pain.
- Used as an analytical standard in qualitative, quantitative, and methodological research experiments.
- Applications include HPLC, GC, and MS.
- Inhibits NMDA receptors.
- Blocks sodium, L-calcium, and potassium channels.
- Potently blocks SCN5A channels.
- Applicable for research into chronic pain.
- Relevant for neuronal signaling, membrane transporter/ion channel research.
- Used in reference standards for metabolism, drug testing, and human metabolites.
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Medchemexpress LLC Maprotiline hydrochloride | 10347-81-6 | 100.0% | 100 MG
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Maprotiline hydrochloride is a highly selective noradrenergic reuptake inhibitor with potent antidepressant, antitumor, and neuropathic pain-relieving effects, demonstrating oral activity. It induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1.
- Inhibits growth and metastasis of Huh7 and HepG2 cells
- Triggers cell apoptosis
- Affects the ERK signaling pathway
- Regulates cholesterol biosynthesis in HCC cells by targeting CRABP1
- Suppresses liver cancer tumor growth in mice
- Reduces neuropathic pain in mice
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Medchemexpress LLC Maprotiline (hydrochloride) | 10347-81-6 | 100.0% | 1 ML
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Maprotiline hydrochloride is a highly selective noradrenergic reuptake inhibitor with strong antidepressant, antitumor, and neuropathic pain-relieving effects. It is orally active and induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1.
- Highly selective noradrenergic reuptake inhibitor
- Exhibits antidepressant, antitumor, and neuropathic pain-relieving effects
- Orally active
- Induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1
- Inhibits growth and metastasis of liver cancer cells
- Regulates cholesterol biosynthesis
- Inhibits tumor growth in liver cancer mouse models without obvious toxicity
- Attenuates neuropathic pain in mice
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Medchemexpress LLC Pilocarpine Hydrochloride | 54-71-7 | MFCD00012722 | 99.92% | 10 G
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Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist. It is provided as a hydrochloride salt, derived from a natural alkaloid, and is primarily used for research purposes.
- Potent M3-type muscarinic acetylcholine receptor agonist
- Research use only
- Stable for shipping at room temperature for less than two weeks
- Store tightly sealed at 4°C, away from moisture and direct sunlight
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Medchemexpress LLC Xylometazoline (hydrochloride) | 1218-35-5 | 99.94% | 25 G
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Xylometazoline hydrochloride is an α-adrenergic receptor agonist with a Ki ranging from 0.05 to 1.7 μM. It constricts nasal blood vessels and increases nasal airflow, making it suitable for research related to nose stuffiness and runny nose. This compound appears as a white to off-white solid.
- Acts as an α-adrenergic receptor agonist
- Constricts nasal blood vessels
- Increases nasal airflow
- Used in research for nose stuffiness and runny nose
- White to off-white solid appearance
- Purity of 99.94%
- Molecular weight of 280.84
- Chemical formula C16H25ClN2
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Medchemexpress LLC Naratriptan (hydrochloride) | 143388-64-1 | 99.7% | 1 ML
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Naratriptan hydrochloride is a selective 5-HT1B/1D receptor agonist known for its peripheral activity and good oral bioavailability. It induces cranial artery vasoconstriction and inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation, reducing sterile inflammation. This compound is primarily used in acute migraine research, focusing on cranial vascular and neuroinflammatory mechanisms.
- Selective 5-HT1B/1D receptor agonist
- Peripherally active with good oral bioavailability
- Induces cranial artery vasoconstriction
- Inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation
- Reduces sterile inflammation
- Targets human recombinant 5-HT1B and 5-HT1D receptors
- Used in research for acute migraine
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Medchemexpress LLC Venlafaxine hydrochloride | 99300-78-4 | MFCD03658865 | 99.8% | 50 MG
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Venlafaxine hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor and an antidepressant, primarily used for research purposes. It targets the Serotonin Transporter in neuronal signaling pathways.
- Potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor.
- Antidepressant properties.
- Active orally.
- Used for research only.
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Medchemexpress LLC Milnacipran hydrochloride | 101152-94-7 | 99.7% | 100 MG
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Milnacipran hydrochloride is an orally active serotonin and norepinephrine reuptake inhibitor. It inhibits monoamine transporters, specifically the norepinephrine transporter and the serotonin transporter, with Ki values of 31 nM and 8.5 nM, respectively. It also inhibits pERK1/2 activation. This compound possesses antidepressant, anxiolytic, and analgesic properties, and has been observed to inhibit biting behavior in mice.
- It is an orally active serotonin and norepinephrine reuptake inhibitor.
- It inhibits monoamine transporters, with notable activity on norepinephrine and serotonin transporters.
- The compound inhibits pERK1/2 activation.
- It demonstrates antidepressant, anxiolytic, and analgesic properties.
- It can be used in studies related to major depressive disorder, anxiety disorders, and neuropathic pain, including fibromyalgia.
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Medchemexpress LLC Rimantadine hydrochloride | 1501-84-4 | 98.0% | 10 G
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Rimantadine hydrochloride (Flumadine hydrochloride) is an orally active inhibitor for M2 protein. It blocks hydrogen ion channel activity, prevents virus entry and replication, and exhibits broad-spectrum antiviral activity. It is for research use only.
- Blocks hydrogen ion channel activity.
- Prevents virus entry and replication.
- Exhibits broad-spectrum antiviral activity.
- Inhibits RNA levels of hepatitis A virus (HAV) in Huh7 and IHH cells.
- Promotes autophagy in HAV-infected Huh7 cells.
- Shows anti-infectious activity in H3N2-infected mouse models when combined with oseltamivir.
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