Halophenols
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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Apexbio Technology LLC TC-H 106 937039-45-7 10mg
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TC-H 106 (CAS 937039-45-7) is a selective inhibitor of class I histone deacetylases (HDACs) targeting HDAC1 HDAC2 HDAC3 and HDAC8 with reported IC50 values of 150 nM 760 nM 370 nM and 5000 nM respectively By inhibiting HDAC activity TC-H 106 interferes with the removal of acetyl groups from histone lysine residues thereby modulating chromatin structure and gene expression In cellular assays TC-H 106 increases histone H3 acetylation in lymphoblastoid cells derived from Friedreich s ataxia (FRDA) patients and enhances frataxin mRNA levels in FRDA mouse models These findings highlight its application in studying epigenetic mechanisms and therapeutic approaches related to HDAC inhibition particularly in neurodegenerative disease models
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eMolecules TRIFLUOROMETHYLTRIMETHYLS 250G
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5000358025 N N -CARBONYLDIIMIDA 250G
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5000412596 TOLPERISONE HYDROCH 5MG
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![Cambridge Isotope Laboratories Benzo[ghi]perylene (13C12 99%) 100 ug/mL in nonane 1 2 mL](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000167877.jpg-250.jpg)
Cambridge Isotope Laboratories Benzo[ghi]perylene (13C12 99%) 100 ug/mL in nonane 1 2 mL
Benzo[ghi]perylene (13C12 99%) 100 ug/mL in nonane 1 2 mL
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Cambridge Isotope Laboratories Parlar 70 (13C10 99%) 10 ug/mL in nonane 1 2 mL
Parlar 70 (13C10 99%) 10 ug/mL in nonane 1 2 mL
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Apexbio Technology LLC Lomerizine HCl 101477-54-7 10mM (in 1mL DMSO)
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Lomerizine HCl (CAS 101477-54-7) is a small molecule antagonist of voltage-gated calcium channels exhibiting inhibitory activity on both L-type and T-type subtypes By modulating calcium influx across neuronal membranes lomerizine HCl is proposed to attenuate neuronal excitability associated with migraine pathophysiology This compound is utilized in biomedical research to investigate calcium channel function and the molecular mechanisms underlying migraine and related neurological disorders
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Apexbio Technology LLC TC-H 106 937039-45-7 50mg
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TC-H 106 (CAS 937039-45-7) is a selective inhibitor of class I histone deacetylases (HDACs) targeting HDAC1 HDAC2 HDAC3 and HDAC8 with reported IC50 values of 150 nM 760 nM 370 nM and 5000 nM respectively By inhibiting HDAC activity TC-H 106 interferes with the removal of acetyl groups from histone lysine residues thereby modulating chromatin structure and gene expression In cellular assays TC-H 106 increases histone H3 acetylation in lymphoblastoid cells derived from Friedreich s ataxia (FRDA) patients and enhances frataxin mRNA levels in FRDA mouse models These findings highlight its application in studying epigenetic mechanisms and therapeutic approaches related to HDAC inhibition particularly in neurodegenerative disease models
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Apexbio Technology LLC Benidipine HCl 91599-74-5 10mM (in 1mL DMSO)
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Benidipine hydrochloride (CAS 91599-74-5) is a dihydropyridine-class small molecule that functions as an inhibitor of voltage-dependent calcium channels thereby modulating calcium influx in vascular smooth muscle and cardiac tissue Additionally benidipine hydrochloride has been shown to suppress mineralocorticoid receptor coactivator (MRC) activation induced by aldosterone This dual inhibitory activity makes it valuable for biomedical research into cardiovascular physiology calcium signaling pathways and the molecular mechanisms underlying mineralocorticoid receptor-associated conditions
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eMolecules 3-BROMOTETRAHYDROFURAN 10G
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5000434661 3-HYDROXYBENZALDEHYD 10G
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