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Filtered Search Results
Medchemexpress LLC Doxifluridine | 3094-09-5 | 99.4% | C9H11FN2O5 | 100 G
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Doxifluridine is a 5-FU prodrug that exhibits anticancer activity. It functions as an inhibitor of thymidine synthase and can enhance tumor inhibition through synergism with various drugs.
- Has anticancer activity
- Functions as a 5-FU prodrug
- Inhibits thymidine synthase
- Enhances tumor inhibition through synergism with other drugs
- Inhibits angiogenesis by significantly inhibiting VEGF expression in FU-MMT-1 cells
- Inhibits cell proliferation in HUVEC cells
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Medchemexpress LLC Faropenem sodium | 122547-49-3 | 98.9% | C12H14NNaO5S | 1 ML
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Faropenem sodium is an orally bioavailable penem antibiotic that regulates inorganic phosphate transporter Npt1. It inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis.
- Orally bioavailable penem antibiotic
- Regulates inorganic phosphate transporter Npt1
- Inhibits M. tuberculosis (MIC of 1.3 μg/mL)
- Inhibits B. anthracis
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Medchemexpress LLC 1-Bromo-3,5-bis(trifluoromethyl)benzene | 328-70-1 | 99.94% | C8H3BrF6 | 1 KG
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1-Bromo-3,5-bis(trifluoromethyl)benzene is a biochemical reagent suitable for use as a biological material or organic compound in life science research. It is also utilized in the preparation of the tetrakis[3,5-bis(trifluoromethyl)phenyl]borate ion.
- Functions as a stabilizing counterion for electrophilic organic and organometallic cations
- Suitable for life science related research
- Can be used as a biological material or organic compound
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Medchemexpress LLC Ibuprofen sodium ((±)-Ibuprofen sodium) | 31121-93-4 | 100.0% | 10 MM * 1 ML
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Ibuprofen sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. This nonsteroidal anti-inflammatory agent and nitric oxide (NO) donor inhibits cell proliferation and angiogenesis, and induces cell apoptosis. It is suitable for research in pain, swelling, inflammation, infection, immunology, and cancer. For research use only.
- Selective COX-1 inhibitor (IC50 of 13 μM)
- Inhibits cell proliferation and angiogenesis
- Induces cell apoptosis
- Nonsteroidal anti-inflammatory agent and nitric oxide (NO) donor
- Supports research in pain, swelling, inflammation, infection, immunology, and cancers
- Also inhibits COX-2 activity (IC50 of 370 μM)
- Demonstrates anti-tumor effects in relevant models
- Attenuates inflammatory responses
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Medchemexpress LLC 2-Hydrazinobenzothiazole | 615-21-4 | 99.95% | C7H7N3S | 50 G
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This product is a potent inhibitor of IDO1, with an IC50 of 8 μM. It functions by interacting with the enzyme's haem through its hydrazine component. This compound shows potential for research related to immune system diseases.
- Potent inhibitory activity against a specific enzyme.
- Interacts with the enzyme's active site via a hydrazine group.
- Suitable for investigation into immune system-related conditions.
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Medchemexpress LLC 1-Methylcyclohexene | 591-49-1 | 96.17 | 250 G
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1-Methylcyclohexene is identified as a male insect sex pheromone, originally sourced from animals, particularly boll weevils. This product is intended for research use only and is not suitable for patient applications.
- Male insect sex pheromone
- For research use only
- Initial source is animals, specifically boll weevils
- Appearance: liquid
- Color: colorless to light yellow
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Medchemexpress LLC Benzhydrol | 91-01-0 | 184.24 | 250 G
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Benzhydrol (Diphenylmethanol) is a biochemical reagent suitable for life science research. It serves as an intermediate in various applications, including pharmaceuticals, agrochemicals, and perfumes. Additionally, it acts as a fixative in the perfume industry and is involved in polymerization reactions as a terminating group. This compound is also a precursor for synthesizing modafinil, benztropine, and diphenhydramine.
- Biochemical reagent for life science research
- Intermediate in pharmaceuticals, agrochemicals, and perfumes
- Used as a fixative in the perfume industry
- Involved in polymerization reactions
- Precursor for modafinil, benztropine, and diphenhydramine synthesis
- High purity of 99.98%
- White to off-white solid appearance
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Medchemexpress LLC ASO 556089 sodium | 96.3% | 5414.60 | 1 MG
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ASO 556089 sodium is a 16 nucleotide length gapmer (3-10-3) that targets the human and mouse long non-coding RNA MALAT1, with the sequence: 5'-GmCATTmCTAATAGmCAGmC-3' (mC:5-methyl cytosine, 3 bases at 3' and 5' ends:constrained ethyl; cEt). This compound is for research use only.
- Targets PCSK9 and MALAT1 in 2D HRPTEC cultures.
- Causes target transcriptional downregulation in HRTEC cultured on chip.
- Inhibits MALAT1 gene expression in 2D HRPTEC culture.
- Does not cause cytotoxicity.
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Medchemexpress LLC NLRP3-IN-21 | 2956791-61-8 | 99.0% | 529.32 | 1 ML
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NLRP3-IN-21 (compound L38) is an NLRP3 inflammasome inhibitor with inflammatory properties. It inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly.
- Inhibits NLRP3 inflammasome activation.
- Suppresses pyroptosis.
- Reduces gasdermin D cleavage.
- Prevents ASC oligomerization.
- Inhibits NLRP3 inflammasome assembly.
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Medchemexpress LLC Zorevunersen sodium (STK-001 sodium) | 2415330-05-9 | 98.3% | 7197.2 (free acid) | 1 MG
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Zorevunersen sodium is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA, which in turn increases the expression of the sodium channel Nav1.1 protein. This compound is primarily used for the study of Dravet syndrome.
- Antisense oligonucleotide for SCN1A mRNA
- Increases Nav1.1 protein expression
- High purity
- Solid, white to off-white appearance
- Soluble in water at concentrations of 20 mg/mL or greater
- For research use only
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Medchemexpress LLC AMPK activator 12 | 431920-24-0 | 99.7% | 426.35 | 1 ML
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AMPK activator 12 (compound 21) is a potent AMPK activator and GDF15 inducer. It increases GDF15 protein levels in human hepatic cells.
- Potent AMPK activator
- GDF15 inducer
- Increases GDF15 protein levels
- Suitable for research use
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Medchemexpress LLC Vidutolimod sodium | 147063-80-7 | 90.2% | 9612.2 | 1 MG
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Vidutolimod sodium is a CpG-A oligodeoxynucleotide and a Toll-like receptor 9 (TLR9) agonist. It is for research use only.
- Activates plasmacytoid dendritic cells (pDCs)
- Triggers interferon alpha (IFNα) release
- Leads to anti-tumor immune effects
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Medchemexpress LLC Sefaxersen sodium | 2272983-11-4 | 99.5% | 8678.96 (free acid) | 1 MG
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Sefaxersen sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). It effectively reduces circulating levels of CFB and can be used for geographic atrophy (GA) research.
- Specific antisense oligonucleotide (ASO)
- Targets complement factor B (CFB)
- Reduces circulating levels of CFB
- Used for geographic atrophy (GA) research
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Medchemexpress LLC AChE-IN-27 | 177028-90-9 | 98.3% | 330.34 | 1 ML
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AChE-IN-27 (compound 8c) is an AChE inhibitor with an IC50 of 0.19 μM. It is suitable for research in neurological diseases such as Alzheimer's disease, dementia, ataxia, and myasthenia gravis.
- AChE inhibitor (IC50=0.19 μM)
- Utilized in studies of neurological diseases
- Applicable for Alzheimer's disease research
- Used in studies for dementia, ataxia, and myasthenia gravis
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Medchemexpress LLC Bepirovirsen sodium | 2563929-84-8 | 92.7% | 7344 (free acid) | 1 MG
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Bepirovirsen sodium is an antisense oligonucleotide targeting all HBV messenger RNAs. It leads to reductions in HBV-derived RNAs, HBV DNA, and viral proteins. Bepirovirsen sodium can be used for the research of chronic HBV infection.
- Targets all HBV messenger RNAs
- Reduces HBV-derived RNAs, HBV DNA, and viral proteins
- Useful for chronic HBV infection research
- Reduces HBV RNA transcripts in HBV-expressing HepG cells (in vitro)
- Dose-dependently reduced hepatic expression of HBV RNA and cytoplasmic hepatitis B core antigen levels in HBV-transgenic mice (in vivo)
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