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Filtered Search Results
Medchemexpress LLC 8-bromo-cGMP sodium | 51116-01-9 | 99.9% | 446.08 | C10H10BrN5NaO7P | 100 MG
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8-Bromo-cGMP sodium is a membrane-permeable cyclic GMP analogue that activates protein kinase G (PKG). Supplied as the sodium salt in solid form at high purity, it is used as a research reagent to probe cGMP signaling pathways, modulate ion channel activity, and study vascular and neuronal responses. Store sealed at -20°C; in solvent, store at -80°C for longer-term stability.
- Membrane-permeable analogue of cGMP that activates protein kinase G (PKG).
- High purity (99.9%) suitable for biochemical and cellular assays.
- Off-white to light yellow solid for straightforward handling.
- Available in lab-scale quantities, including 100 MG.
- Stable when stored sealed at -20°C; in solvent, store at -80°C for up to 6 months.
- Used to study cGMP signaling, ion channel modulation, and vascular or neuronal pharmacology.
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Medchemexpress LLC 5-Bromo-N- 4 6-dime 5g | 5G
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5-Bromo-N- 4 6-dime 5g | 5G
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Medchemexpress LLC 5-(1,3-benzodioxol-5-ylmethylene)-2,4-thiazolidinedione | 6318-41-8 | MFCD18382117 | 99.0% | 249.24 g/mol | C11H7NO4S | 1 ML
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AS-041164 is a potent, selective, orally active PI3Kγ inhibitor supplied either as a ready-to-use solution (10 mM in DMSO, 1 mL) or as a solid in multiple mg sizes for research applications investigating PI3Kγ signaling and inflammatory responses.
- Potent, selective PI3Kγ inhibition with IC50 ≈ 70 nM.
- Available as 10 mM solution (1 mL) or solids in multiple milligram sizes.
- High purity (≈99.0%) suitable for research use.
- Soluble in DMSO, convenient for in vitro assays.
- Store protected from light; in solvent conditions extend stability at low temperatures.
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Medchemexpress LLC Guadecitabine sodium | 929904-85-8 | C18H23N9NaO10P | 1 ML
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Guadecitabine sodium is a second-generation DNA methyltransferases (DNMT) inhibitor for research of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). It is for research use only and not sold to patients.
- Second-generation DNA methyltransferases (DNMT) inhibitor
- Induces dose-dependent increase in p16 expression
- Inhibits DNA methylation
- Effective in reducing DNA methylation and retarding tumor growth in vivo
- Reactivates p16 gene expression
- Better tolerated in vivo than 5-Aza-CdR
- Involved in numerous clinical trials for various conditions
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Research Products International Corp 4Nitro beta Dxylopyrano 5G
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Free PNP: <50ppm
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Medchemexpress LLC 100 bp DNA marker | 250 UL
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The 100 bp DNA Marker is provided in a solution of 1x DNA Loading Buffer and can be directly used for nucleic acid electrophoresis analysis. It contains 10 double-stranded DNA fragments ranging from 100 bp to 1000 bp. A 5 μL aliquot of this product contains approximately 120 ng for the 500 bp band and about 50 ng for the other bands, which is useful for quantitative analysis.
- Provided in 1x DNA loading buffer
- Directly usable for nucleic acid electrophoresis analysis
- Contains 10 double-stranded DNA fragments
- Fragments range from 100 bp to 1000 bp
- 5 μL of the product contains approximately 120 ng for the 500 bp band and about 50 ng for the other bands
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Medchemexpress LLC Polyethylene glycol 500 | 25322-68-3 | 500.00 | (C2H4O)nH2O | 500g
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PEG500 (Polyethylene glycol 500) is a versatile polymer that s used as a solvent dispersant lubricant and more in industries like pharmaceuticals and biotechnology and it can also modify liposomes PEG500 is commonly used as a solvent or carrier for drugs helping with capsule endoscopy to improve image quality and cecum completion rates[1][2]
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Medchemexpress LLC Recombinant human interleukin-21 (rHu IL-21) | >95.0% | 2UG
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Recombinant human interleukin-21 (rHu IL-21) is a tag-free, lyophilized cytokine produced in E. coli representing residues Q32-S162 of the human protein. It is provided with >95% purity and low endotoxin, and is intended for receptor binding studies, cell-based assays, and functional activity testing.
- Tag-free recombinant human sequence (Q32-S162).
- Lyophilized powder for convenient storage and handling.
- Purity greater than 95% by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg).
- Predicted molecular mass 15.6 kDa; observed ~15.4-18.0 kDa by SDS-PAGE.
- Demonstrated biological activity with ED50 <0.5 ng/mL in cell assays.
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Medchemexpress LLC Polyvinyl alcohol | 9002-89-5 | MFCD00081922 | 205000 (Average) | (C2H4O)n | 25g
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PVA (Polyvinyl alcohol) (Mw 205000) is a polyvinyl alcohol with a molecular weight of 205000 which is used as a biological excipient PVA (Mw 205000) has excellent optical properties high dielectric strength and excellent charge storage and can be used as an embedded pad and substrate for metal/inorganic nanofillers for sensing optoelectronic devices and many other applications[1]
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Medchemexpress LLC Acridone | 578-95-0 | 195.22 | 100 G
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Acridone is an organic compound derived from the acridine skeleton, known for its diverse biological activities. It has been observed to possess antibacterial, antimalarial, antiviral, and anti-neoplastic properties. This versatile compound has also been shown to inhibit the proliferation of human breast cancer cells in vitro and to block the expression of ATP binding cassette subfamily G member 2 (ABCG2) at both mRNA and protein levels, highlighting its potential in various research applications.
- Organic compound based on the acridine skeleton.
- Exhibits antibacterial properties.
- Possesses antimalarial activity.
- Demonstrates antiviral effects.
- Shows anti-neoplastic activities.
- Inhibits proliferation of human breast cancer cells.
- Blocks expression of ATP binding cassette subfamily G member 2 (ABCG2).
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Medchemexpress LLC DMNB | 20357-25-9 | 100.0% | 211.17 | C9H9NO5 | 25 G
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DMNB (6-nitroveratraldehyde) is a high-purity chemical intermediate used as a precursor in radiochemical synthesis, notably for preparing no-carrier-added 6-[18F]fluoro-L-DOPA for PET studies. The solid reagent is provided with analytical documentation and recommended storage to preserve stability for research applications.
- High purity: 99.98% (HPLC).
- Chemical formula C9H9NO5 and molecular weight 211.17.
- Used as a precursor for synthesis of no-carrier-added 6-[18F]fluoro-L-DOPA.
- Storage: store at 4°C under inert atmosphere; in solvent: -80°C (6 months), -20°C (1 month).
- Supplied with a certificate of analysis and safety data sheet.
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Medchemexpress LLC Activin Receptor Type IIB Antibody (YA2345) | 10 UL
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Activin Receptor Type IIB (ACVR2B) is a transmembrane serine/threonine kinase that forms an activin receptor complex with type I receptors. It functions as the primary receptor for activin-A, activin-B, and inhibin-A, regulating diverse processes including neuronal differentiation/survival, hair follicle cycling, pituitary FSH production, wound healing, extracellular matrix formation, immunosuppression and carcinogenesis. Upon activation, ACVR2B phosphorylates type I receptors to initiate SMAD2/SMAD3-SMAD4-mediated transcriptional regulation.
- Derived from rabbit host
- Reacts with human, mouse, and rat samples
- Non-conjugated
- SwissProt ID: Q13705
- Research field: Signal Transduction
- Liquid appearance
- Application: WB (1:500-1:1000 dilution)
- Storage at -20°C for 1 year; avoid repeated freeze/thaw cycles
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Medchemexpress LLC N, N, N′, N′-tetramethyl (succinimido) uronium tetrafluoroborate | 105832-38-0 | ≥99.0% | 301.05 | 100 G
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TSTU is a coupling reagent utilized in peptide chemistry. It facilitates the conversion of carboxylic acids into their corresponding N-hydroxysuccinimidyl (NHS) esters. TSTU is suitable for the in situ formation of succinimide esters in mixed aqueous/organic media for amide bond formation reactions.
- Can be applied for attaching labels to peptides, proteins, and other molecules.
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Cambridge Isotope Laboratories Heptachlor (13C10 99%) 100 ug/mL in nonane 1 2 mL
Heptachlor (13C10 99%) 100 ug/mL in nonane 1 2 mL
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Medchemexpress LLC ADAMTS13 Human CHO 100ug | 100ug
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The ADAMTS13 protein a metalloproteinase has a metalloproteinase domain a disintegrin-like domain and a thrombospondin type 1 motif It cleaves von Willebrand Factor and defects in this gene cause thrombotic thrombocytopenic purpura Alternative splicing generates multiple transcript variants ADAMTS13 is broadly expressed in various tissues including the liver testis and 24 other tissues ADAMTS13 Protein Human (CHO His) is the recombinant human-derived ADAMTS13 expressed by CHO with C-10 His labeled tag The total length of ADAMTS13 Protein Human (CHO His) is 655 a a
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