Halophenols
Medchemexpress LLC PTP Inhibitor 1 | 2632-13-5 | 99.55% | 229.07 | 10 G
PTP inhibitor 1 is a protein tyrosine phosphatase (PTP) inhibitor that exhibits an anti-angiogenic effect. It is intended for research use only.
- Inhibits PTP.
- Shows anti-angiogenic activity with an IC50 of 3.7 μM for HUVECs.
Medchemexpress LLC Copanlisib dihydrochloride | 1402152-13-9 | C23H30Cl2N8O4 | 1 ML
Copanlisib dihydrochloride is a potent, selective, and ATP-competitive pan-class I PI3K inhibitor. It demonstrates over 2,000-fold selectivity against other lipid and protein kinases, excluding mTOR, and exhibits superior antitumor activity.
- Induces apoptosis in BT20 breast cancer cells
- Inhibits PI3K-mediated AKT phosphorylation in ELT3 cells
- Potently inhibits cell proliferation in human tumor cell lines
- Shows robust antitumor activity in athymic nude rats injected with KPL4 tumor cells
Medchemexpress LLC Defibrotide sodium | 83712-60-1 | 90.0% | 13-20 KDa | 50 MG
Defibrotide sodium | 83712-60-1 | 90.0% | 13-20 KDa | 50 MG
Medchemexpress LLC Dapiprazole (hydrochloride) | 72822-13-0 | 99.3% | C19H28ClN5 | 1 ML
Dapiprazole hydrochloride is a potent, selective, and orally active alpha-1 adrenoceptor antagonist. It is noted for suppressing opioid withdrawal symptoms and is also used in eye drops to reverse mydriasis. This product is for research use only.
- Potent, selective alpha-1 adrenoceptor antagonist
- Suppresses opioid withdrawal symptoms
- Used to reverse mydriasis
- Provided as a 10 mM, 1 mL solution in DMSO
- Purity: 99.3%
- Stable under recommended storage conditions
- White to off-white solid appearance
Medchemexpress LLC Amisulpride hydrochloride | 81342-13-4 | 99.79% | C17H28ClN3O4S | 1 ML
Amisulpride hydrochloride is a potent dopamine D2/D3 receptor antagonist, demonstrating Ki values of 2.8 nM and 3.2 nM for human dopamine D2 and D3 receptors, respectively. This compound is known to inhibit quinpirole-elicited [3H]thymidine incorporation and subtly enhance [3H]dopamine release from rat striatum slices. It is primarily intended for research applications.
- Dopamine D2/D3 receptor antagonist
- Targets human dopamine D2 and D3 receptors
- Inhibits quinpirole-elicited [3H]thymidine incorporation
- Increases [3H]dopamine release
- Involved in GPCR/G Protein pathway
- Involved in Neuronal Signaling pathway
Medchemexpress LLC Ethanone, 2-bromo-1-(4-methoxyphenyl)- | 2632-13-5 | 98.9% | 229.07 | 25 G
PTP inhibitor 1 is a protein tyrosine phosphatase (PTP) inhibitor that exhibits anti-angiogenic effects. It is intended for research use only.
- Purity: 99.55%
- Anti-angiogenic effect: Exhibits anti-angiogenic activity with an IC50 of 3.7 μM for HUVECs.
Medchemexpress LLC Pregnenolone (3β-Hydroxy-5-pregnen-20-one) | 145-13-1 | >99.9% | 25 G
Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a potent neurosteroid and the primary precursor for various steroid hormones, including steroid ketones. It functions as a signaling-specific inhibitor of the cannabinoid CB1 receptor, thereby inhibiting the effects of tetrahydrocannabinol (THC) that are mediated by CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Additionally, it acts as a TRPM3 channel activator and can weakly activate TRPM1 channels.
- Potent neurosteroid
- Primary precursor for various steroid hormones
- Signaling-specific inhibitor of CB1 receptor
- Inhibits THC effects mediated by CB1 receptors
- Protects the brain from cannabis intoxication
- Acts as a TRPM3 channel activator
- Weakly activates TRPM1 channels
Cambridge Isotope Laboratories 3 4-DiBDE (BDE-13) (unlabeled) 50 ug/mL in nonane 1 2 mL
3 4-DiBDE (BDE-13) (unlabeled) 50 ug/mL in nonane 1 2 mL
Medchemexpress LLC L-ornithine hydrochloride | 3184-13-2 | MFCD00064562 | 99.9% | 168.62 g·mol⁻1 | C5H13ClN2O2 | 500 MG
L-ornithine hydrochloride is a research-grade, non-proteinogenic amino acid used in studies of nitrogen metabolism and the urea cycle. Supplied as a white to off-white solid, the material is provided with batch-specific quality documentation for laboratory and analytical use.
- High purity (~99.9%) for research and analytical applications.
- Used in urea cycle and nitrogen metabolism studies.
- White to off-white solid, facile handling and weighing.
- Available in small laboratory sizes, including 500 mg.
- Provided with batch-specific certificate of analysis for traceability.
Medchemexpress LLC PG 116800 | 291533-11-4 | 99.8% | C24H27N3O7S | 1 MG
PG 116800 is an orally active MMP inhibitor. It demonstrates high affinity for MMP-2, -3, -8, -9, -13, and -14, with substantially lower affinity for MMP-1 and -7. This compound can be utilized in research pertaining to knee osteoarthritis.
- Orally active MMP inhibitor
- High affinity for MMP-2, -3, -8, -9, -13, and -14
- Lower affinity for MMP-1 and -7
- Can be used for knee osteoarthritis research
Medchemexpress LLC Adrenergic a2C receptor agonist-1 | 24155-42-8 | 257.12 | 500 G
Adrenergic a2C receptor agonist-1 (compound 13) is an agonist targeting the adrenergic receptor a2C.
- Available in sizes: 50 g, 100 g, 500 g.
- In-stock availability for listed sizes.
Medchemexpress LLC Adrenergic a2C receptor agonist-1 | 24155-42-8 | 257.12 | 100 G
Adrenergic a2C receptor agonist-1 (compound 13) is an agonist targeting the adrenergic receptor a2C. It is for research use only and not for sale to patients.
- Agonist targeting the adrenergic receptor a2C.
- Solid appearance, white to off-white color.
Medchemexpress LLC PF-07038124 hydrochloride | 2415317-57-4 | 99.3% | C18H23BClNO4 | 1 MG
PF-07038124 hydrochloride is a potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. It demonstrates immunomodulatory effects by inhibiting IL-13, IL4, and IFNγ, making it suitable for research related to atopic dermatitis and plaque psoriasis. This compound has been investigated in Phase 1 and Phase 2 clinical trials for these conditions. It is supplied as an off-white to light yellow solid.
- Specifically targets PDE4B2 with high potency
- Shows inhibitory activity against IL-13, IL4, and IFNγ
- Used in the study of atopic dermatitis and plaque psoriasis
- Investigated in Phase 1 and Phase 2 clinical trials
- Soluble in DMSO at 100 mg/mL
- Recommended storage is 4°C sealed, away from moisture
Medchemexpress LLC Zika virus E/envelope protein | 5 UG
Recombinant Zika virus envelope (E) protein fragment (residues V593-K699) expressed in HEK293 cells with a His tag, supplied as a 0.22 μm filtered PBS solution for research use. The fragment is ~107 amino acids (~13 kDa) with endotoxin <1 EU/μg; store at -80°C and avoid repeated freeze-thaw cycles.
- Expressed in HEK293 human cells for mammalian post-translational modifications.
- His tag facilitates purification and detection.
- Supplied as a sterile 0.22 μm filtered PBS solution.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Fragment corresponds to residues V593-K699 (≈107 aa, ~13 kDa).
- Stable long-term at -80°C; avoid repeated freeze-thaw cycles.
Medchemexpress LLC Ibuprofen sodium ((±)-Ibuprofen sodium) | 31121-93-4 | 100.0% | 10 MM * 1 ML
Ibuprofen sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. This nonsteroidal anti-inflammatory agent and nitric oxide (NO) donor inhibits cell proliferation and angiogenesis, and induces cell apoptosis. It is suitable for research in pain, swelling, inflammation, infection, immunology, and cancer. For research use only.
- Selective COX-1 inhibitor (IC50 of 13 μM)
- Inhibits cell proliferation and angiogenesis
- Induces cell apoptosis
- Nonsteroidal anti-inflammatory agent and nitric oxide (NO) donor
- Supports research in pain, swelling, inflammation, infection, immunology, and cancers
- Also inhibits COX-2 activity (IC50 of 370 μM)
- Demonstrates anti-tumor effects in relevant models
- Attenuates inflammatory responses