Halophenols
Apexbio Technology LLC NPS-1034 1221713-92-3 25mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Apexbio Technology LLC NPS-1034 1221713-92-3 5mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Apexbio Technology LLC NPS-1034 1221713-92-3 10mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Apexbio Technology LLC NPS-1034 1221713-92-3 50mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Apexbio Technology LLC NPS-1034 1221713-92-3 100mg
NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
Medchemexpress LLC Methicillin sodium salt | 132-92-3 | 98.1% | 1 ML
Methicillin sodium salt is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotics. It inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. This compound inhibits *S. aureus* with a MIC value of 2.1 μg/mL and is suitable for inflammation research.
- Semi-synthetic β-lactam antibiotic
- Inhibits penicillin-binding proteins
- Effectively eliminates S. aureus
- Suitable for inflammation research
- Improves survival in infected animal models
Apexbio Technology LLC Eletriptan HBr 177834-92-3 10mM (in 1mL DMSO)
Eletriptan hydrobromide (CAS 177834-92-3) is an orally bioavailable small molecule that acts as a selective agonist for the 5-hydroxytryptamine (serotonin) 5-HT1B and 5-HT1D receptors By activating these receptor subtypes eletriptan hydrobromide modulates cranial blood vessel tone and neuronal signaling implicated in migraine pathophysiology This compound is commonly utilized in preclinical and clinical research to investigate serotonergic modulation of neurovascular function and to explore therapeutic mechanisms relevant to migraine and related neurovascular disorders
eMolecules 3-AMINO-5-FLUOROPHENOL | 1167055-92-6 | MFCD12405141 | 1g
AstaTech | 3-AMINO-5-FLUOROPHENOL | 1g | 569109725 | AT15770 | 95.000 | 1167055-92-6 | MFCD12405141 | 127.118 | C6H6FNO
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Medchemexpress LLC NPS-1034 | 1221713-92-3 | 98.0% | 551.54 | C31H23F2N5O3 | 10 MG
NPS-1034 is a small-molecule dual inhibitor of the receptor tyrosine kinases AXL and MET. It exhibits IC50 values of 10.3 nM (AXL) and 48 nM (MET) and is supplied for research use as a solid powder or as a 10 mM solution in DMSO.
- Dual inhibition of AXL and MET with low-nanomolar potency.
- High purity (98.0%) suitable for biochemical and cellular assays.
- Available as solid powder or DMSO solution for assay flexibility.
- Supplied in multiple package sizes to fit experimental needs.
- Useful for studying MET/AXL signaling and drug resistance mechanisms.
Medchemexpress LLC Thianthrene | 92-85-3 | MFCD00005065 | 100.0% | 216.32 g/mol | C12H8S2 | 25 G
Thianthrene (CAS 92-85-3) is a sulfur-containing tricyclic research chemical used in biochemical assays and reported as an inhibitor of Leishmania donovani pteridine reductase 1 (PTR1). It is supplied for research and analytical applications with high reported purity and is available in solution and solid forms to support various laboratory workflows.
- High purity suitable for biochemical research.
- Reported PTR1 inhibitory activity for parasite biology studies.
- Available as DMSO solution and solid quantities for experimental flexibility.
- Intended for research and analytical applications only.
- Provided with a safety data sheet and handling documentation.
Medchemexpress LLC NPS-1034 | 1221713-92-3 | 98.0% | 551.54 g/mol | C31H23F2N5O3 | 25 MG
NPS-1034 is a small-molecule dual inhibitor of the receptor tyrosine kinases AXL and MET, used in research to probe MET/AXL-driven signaling and resistance mechanisms. It exhibits low-nanomolar potency against both targets and is provided as a high-purity powder for in vitro and preclinical studies.
- Dual inhibition of AXL and MET for pathway studies.
- Low-nanomolar potency: AXL IC50 = 10.3 nM, MET IC50 = 48 nM.
- High purity supports reproducible experimental results.
- Supplied as a powder with defined storage conditions.
- Suitable for in vitro kinase assays and cell-based studies.
- Available in small research quantities for preclinical use.
Medchemexpress LLC NPS-1034 | 1221713-92-3 | 98.0% | 551.54 g/mol | C31H23F2N5O3 | 1 ML
NPS-1034 is a small-molecule dual inhibitor of the receptor tyrosine kinases AXL and MET, exhibiting low-nanomolar biochemical potency (AXL IC50 = 10.3 nM; MET IC50 = 48 nM). It is supplied for research use in formats including solid powder and ready-to-use 10 mM solution in DMSO, and is characterized by CAS 1221713-92-3 and molecular weight 551.54 g/mol.
- Dual inhibition of AXL and MET with low-nanomolar potency.
- Suitable for in vitro kinase and cell-based studies.
- Available as solid powder or 10 mM DMSO solution for convenience.
- Characterized by CAS 1221713-92-3 and molecular weight 551.54 g/mol.
- High purity (98.0%) for consistent experimental results.
Medchemexpress LLC Nps-1034 | 1221713-92-3 | 98.0% | 551.54 g/mol | C31H23F2N5O3 | 50 MG
NPS-1034 is a small-molecule, research-use inhibitor targeting the receptor tyrosine kinases AXL and MET. It inhibits AXL with an IC50 of 10.3 nM and MET with an IC50 of 48 nM, and is supplied as a powder for laboratory studies to probe MET/AXL signaling and evaluate anti-tumor activity.
- Potent dual kinase inhibition: AXL IC50 10.3 nM, MET IC50 48 nM.
- High purity suitable for research (98.0%).
- Supplied as powder for flexible dosing and formulation.
- DMSO solubility approximately 34 mg/mL; ultrasonic assistance recommended.
- Storage stability: powder stable at -20°C for long-term storage.
Medchemexpress LLC 1-(4-fluorophenyl)-N-[3-fluoro-4-(3-phenylpyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2,3-dimethyl-5-oxo | 1221713-92-3 | MFCD29905447 | 98.0% | 551.54 | C31H23F2N5O3 | 100 MG
NPS-1034 is a small-molecule dual inhibitor of the receptor tyrosine kinases AXL and MET intended for preclinical research. It exhibits low-nanomolar biochemical potency and is used to probe AXL/MET signaling and evaluate anti-tumor efficacy in cell-based and in vivo models.
- Dual AXL and MET inhibition with low-nanomolar potency (AXL ≈10.3 nM; MET ≈48 nM).
- Suitable for cell-based assays and in vivo oncology studies.
- High chemical purity (>98.0%).
- Molecular formula C31H23F2N5O3 and molecular weight 551.54 g/mol.
- Available in multiple pack sizes and solution formats for experimental flexibility.