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Filtered Search Results
eMolecules EMOLECULES INC
5000470874 BENZYL PROPIOLATE 5G
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | 99.9% | 50 MG
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Cediranib maleate is a highly potent, orally available VEGFR inhibitor. It effectively inhibits VEGF-stimulated proliferation and KDR phosphorylation in human umbilical vein endothelial cells and reduces vessel sprouting in coculture models. In vivo, it ablates experimental angiogenesis and inhibits the growth of various human tumor xenografts.
- Highly potent, orally available VEGFR inhibitor
- Inhibits VEGF-stimulated proliferation and KDR phosphorylation
- Reduces vessel area, length, and branching at subnanomolar concentrations
- Ablates experimental angiogenesis
- Inhibits growth of established human tumor xenografts
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Medchemexpress LLC Ilginatinib maleate | 1354799-87-3 | 99.9% | 505.50 | 25 MG
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Ilginatinib maleate | 1354799-87-3 | 99.9% | 505.50 | 25 MG
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Medchemexpress LLC Pimethixene maleate | 13187-06-9 | MFCD00079242 | 99.7% | 1 ML
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Pimethixene maleate is an antihistamine and antiserotonergic compound that functions as an antimigraine agent. It is a potent antagonist for several receptors, including 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4, as well as muscarinic M1 and M2 receptors. It is intended for research use only.
- Antihistamine and antiserotonergic compound
- Acts as an antimigraine agent
- Potent antagonist of various receptors (5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4, muscarinic M1 and M2)
- Molecular weight: 409.50
- Formula: C23H23NO4S
- Appearance: Solid
- Color: White to off-white
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eMolecules 922-67-8 | Methyl propiolate | Synthonix | MFCD00008572 | 84.074 | C4H4O2 | 95.000 | COC(=O)C#C | 1g | 649427584
Methyl propiolate | Synthonix | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 95.000 | COC(=O)C#C | 1g | 649427584
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Medchemexpress LLC Cipralisant maleate 50mg | 223420-20-0 | 50MG
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Cipralisant (GT-2331) (maleate) is an orally active low-toxicity potent selective high affinity histamine H3 receptor full antagonist in vivo and an agonist in vitro with a pKi of 9 9 for histamine H3 receptor and a Ki of 0 47 nM for rat histamine H3 receptor Cipralisant (maleate) has the potential for attention-deficit hyperactivity disorder research[1 [2 [3 [4 Cipralisant (maleate) is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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(C)OCc1cc(ccn1)B1OC(C)(C)C(C)(C)O1 | 100mg | 714081920](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502428083.PNG-250.jpg)
eMolecules 880495-84-1 | 2-(((tert-Butyldimethylsilyl)oxy)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | Ambeed | MFCD11617859 | 349.350 | C18H32BNO3Si | 98.000 | CC(C)(C)[Si](C)(C)OCc1cc(ccn1)B1OC(C)(C)C(C)(C)O1 | 100mg | 714081920
2-(((tert-Butyldimethylsilyl)oxy)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | Ambeed | 880495-84-1 | MFCD11617859 | 349.350 | C18H32BNO3Si | 98.000 | CC(C)(C)[Si](C)(C)OCc1cc(ccn1)B1OC(C)(C)C(C)(C)O1 | 100mg | 714081920
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Selleck Chemical LLC Edonerpic maleate
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Edonerpic maleate (T-817) is a novel neurotrophic agent which can inhibit amyloid- peptides (A )
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 10mM (in 1mL DMSO)
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NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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Medchemexpress LLC Setiptiline maleate | 85650-57-3 | 99.9% | 377.43 | 1 ML
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Setiptiline maleate is a tetracyclic antidepressant (TeCA) that functions as a noradrenergic and specific serotonergic antidepressant (NaSSA). It acts as a norepinephrine reuptake inhibitor and an α2-adrenergic receptor antagonist, as well as a serotonin receptor antagonist, likely affecting the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes. It also functions as an H1 receptor inverse agonist/antihistamine, making it suitable for research applications.
- High purity (99.94%) for reliable research
- Well-characterized pharmacological actions
- Inhibits norepinephrine reuptake
- Antagonizes α2-adrenergic receptors
- Antagonizes serotonin receptors (5-HT2A, 5-HT2C, and/or 5-HT3)
- Acts as an H1 receptor inverse agonist/antihistamine
- Detailed solubility information and protocols for in vitro and in vivo studies
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Apexbio Technology LLC Paroxetine maleate 64006-44-6 50mg
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Paroxetine maleate (CAS 64006-44-6) is a selective serotonin reuptake inhibitor (SSRI) that blocks the reabsorption of serotonin into presynaptic neurons resulting in elevated synaptic serotonin levels and modulation of neurotransmission This compound is widely utilized in the investigation of serotonergic signaling related to anxiety disorders including generalized anxiety disorder post-traumatic stress disorder and premenstrual dysphoric disorder Additionally paroxetine maleate serves as a research tool in studies probing the neuropharmacological mechanisms of chronic headache and its prospective therapeutic interventions
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TARGETMOL CHEMICALS INC Ciproxifan maleate 10MG
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Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Ciproxifan maleate (FUB 359)(FUB-359 maleate) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. Purity 99.45%
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Medchemexpress LLC Zaldaride maleate | 109826-27-9 | 99.7% | 544.60 g/mol | C30H32N4O6 | 1 ML
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Zaldaride maleate is a potent, orally active, and selective calmodulin inhibitor provided as a solid and as a ready-to-use 10 mM solution (1 mL). It is supplied with high reported purity and a documented IC50 in the low nanomolar range, and is intended for biochemical and pharmacological research involving calmodulin-mediated pathways. Store sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
- Potent calmodulin inhibitor with low-nanomolar activity.
- Offered as a solid and as a 10 mM solution (1 mL) for convenience.
- High reported purity suitable for research use.
- Molecular weight approximately 544.60 g/mol.
- Storage guidelines for sealed material and solutions provided.
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Apexbio Technology LLC Paroxetine maleate 64006-44-6 10mg
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Paroxetine maleate (CAS 64006-44-6) is a selective serotonin reuptake inhibitor (SSRI) that blocks the reabsorption of serotonin into presynaptic neurons resulting in elevated synaptic serotonin levels and modulation of neurotransmission This compound is widely utilized in the investigation of serotonergic signaling related to anxiety disorders including generalized anxiety disorder post-traumatic stress disorder and premenstrual dysphoric disorder Additionally paroxetine maleate serves as a research tool in studies probing the neuropharmacological mechanisms of chronic headache and its prospective therapeutic interventions
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Apexbio Technology LLC L-693,403 maleate 207455-21-8 50mg
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L-693 403 maleate (CAS 207455-21-8) is a small molecule exhibiting high affinity and selectivity for sigma ( ) receptors By modulating receptor-mediated signaling pathways it influences neuronal signal transduction at the molecular level Preclinical studies indicate that L-693 403 maleate possesses analgesic properties likely through its regulatory effects on neural activity Owing to these pharmacological characteristics it is utilized in exploratory research on neurological disorders supporting its value as a tool compound in the investigation of neural modulation mechanisms
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