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Filtered Search Results
Medchemexpress LLC Zamifenacin fumarate | 127308-98-9 | 99.0% | 531.60 g/mol | C31H33NO7 | 5 MG
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Zamifenacin fumarate is the fumarate salt of zamifenacin (UK-76654), a gut-selective muscarinic M3 receptor antagonist used in research to study gastrointestinal motility. It is provided as a high-purity solid for use in in vitro and in vivo pharmacology studies targeting colonic motility.
- Potent gut-selective muscarinic M3 receptor antagonist that reduces colonic motility.
- High purity suitable for research applications (99.0%).
- Solid, white to off-white form for convenient handling and dosing.
- Molecular weight 531.60 g/mol, molecular formula C31H33NO7.
- Recommended storage at 4°C; in solution, -80°C for long-term stability.
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Medchemexpress LLC Tegaserod maleate | 189188-57-6 | 99.9% | C20H27N5O5 | 50 MG
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Tegaserod maleate is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. This compound induces tumor cell apoptosis, attenuates PI3K/Akt/mTOR signaling, and reduces S6 phosphorylation. It demonstrates anti-tumor activity and is being investigated for its potential in irritable bowel syndrome (IBS) research.
- Orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist
- 5-HT2B receptor antagonist
- Induces tumor cell apoptosis
- Attenuates PI3K/Akt/mTOR signaling
- Reduces S6 phosphorylation
- Demonstrates anti-tumor activity
- Potential for irritable bowel syndrome (IBS) research
- For research use only
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Medchemexpress LLC Edonerpic (maleate) | 519187-97-4 | 99.8% | 407.48 | 25 MG
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Edonerpic maleate is a novel neurotrophic agent that inhibits amyloid-β peptides (Aβ). It has been shown to preserve cortical neurons in the presence of Aβ(1-42) and prevent oxidative stress-induced neuronal death.
- Prevents oxidative stress-induced neuronal death.
- Almost completely prevents GSH reduction.
- Significantly increases neurite length in hippocampal slices.
- Ameliorates deficits in adult neurogenesis and spatial memory in rats.
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Pfaltz & Bauer Diethylacetylene dicarboxylate 5G | 762-21-0
Diethylacetylene dicarboxylate 5G | 762-21-0
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Medchemexpress LLC U-99194 (maleate) | 234757-41-6 | 99.2% | 25 MG
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U-99194 maleate is a selective, potent dopamine D3 receptor antagonist with a Kᵢ of 160 nM. It inhibits the activation of the D3 receptor mediated by endogenously released dopamine or exogenous D3 agonists. This compound can be used for the study of dopamine D3 receptor-mediated motor disorders, particularly kinetic tremors.
- Selective, potent dopamine D3 receptor antagonist
- Inhibits activation of D3 receptor
- Abrogates the IPSC-suppressive effect of D3 agonists
- Significantly suppresses Nicotine-induced tremor in mice
- Useful for studying dopamine D3 receptor-mediated motor disorders
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Medchemexpress LLC Ro 25-6981 Maleate | 1312991-76-6 | 99.25% | 455.54 | 100 MG
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Ro 25-6981 Maleate is a potent, selective, and activity-dependent NR2B subunit-specific NMDA receptor antagonist. It demonstrates anticonvulsant and anti-parkinsonian activity and has potential for research into Parkinson's disease.
- Potent, selective, and activity-dependent NR2B subunit-specific NMDA receptor antagonist
- Demonstrates anticonvulsant activity
- Demonstrates anti-parkinsonian activity
- Potential for Parkinson's disease research
- Induces contraversive rotations in 6-OHDA-lesioned rats
- Exhibits age- and activation-dependent anticonvulsant action
- Shows analgesic effects on incision pain in rats
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Medchemexpress LLC Zaldaride maleate | 109826-27-9 | MFCD04113002 | 99.7% | 544.60 | C30H32N4O6 | 1 MG
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Zaldaride maleate is a potent, orally active, and selective calmodulin inhibitor used in biochemical and cellular research. It inhibits calmodulin-stimulated cAMP phosphodiesterase activity (IC50 ≈ 3.3 nM), modulates ion-channel currents, and is supplied for laboratory research use only.
- Potent calmodulin inhibitor.
- Orally active in pharmacological studies.
- Low nanomolar IC50 for cAMP phosphodiesterase inhibition.
- Reversibly blocks voltage-activated Na+, Ca2+, and K+ currents.
- High purity suitable for research applications.
- Provided as a small solid quantity for laboratory use.
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Apexbio Technology LLC Flupirtine maleate 75507-68-5 10mM (in 1mL DMSO)
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Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
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Medchemexpress LLC (S)-Timolol (Maleate) | 26921-17-5 | 99.8% | 432.49 | 25 MG
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(S)-Timolol maleate is a non-cardioselective hydrophilic β-adrenoceptor blocker, widely used as a standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. It also finds application in hypertension, angina pectoris, and myocardial infarction. This product is suitable for research and analytical applications.
- Non-cardioselective hydrophilic β-adrenoceptor blocker
- Prevents production of aqueous humor
- Used for intraocular pressure (glaucoma)
- Can be used for hypertension
- Can be used for angina pectoris
- Can be used for myocardial infarction
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Apexbio Technology LLC Rosiglitazone maleate(Synonyms: Avandia, BRL 49653, BRL49653C, Rosiglitazone maleate salt, BRL49653, RGZ, Rosiglizole maleate), 25mg, CAS: 155141-29-0.
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Rosiglitazone maleate (CAS 155141-29-0) is the maleate salt formulation of rosiglitazone a thiazolidinedione compound targeting the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR ) By selective activation of PPAR rosiglitazone increases insulin sensitivity of peripheral tissues facilitating glucose uptake and reduction of blood glucose levels Due to its insulin-sensitizing activity rosiglitazone maleate serves as an important research tool in diabetes and metabolic syndrome investigations However recent clinical studies also report associations with adverse cardiovascular events fluid retention and anemia underscoring considerations for risk-benefit evaluation in ongoing research
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Medchemexpress LLC ER-27319 maleate | 1204480-26-1 | 99.4% | 396.44 g/mol | C22H24N2O5 | 5 MG
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ER-27319 maleate is an acridone-derivative small molecule that acts as a potent, selective spleen tyrosine kinase (Syk) inhibitor. It inhibits Syk tyrosine phosphorylation and activity, and suppresses antigen-induced release of allergic mediators from human and rat mast cells (reported IC50 ≈ 10 μM). The compound is supplied as the maleate salt in solid form for research use.
- Potent, selective Syk inhibitor.
- Inhibits tyrosine phosphorylation of Syk.
- Suppresses antigen-induced mediator release from mast cells (IC50 ≈ 10 μM).
- Provided as the maleate salt in solid form for laboratory use.
- Characterized molecular properties: C22H24N2O5, MW 396.44 g/mol.
- Intended for research applications in Syk-mediated signaling and allergy models.
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Medchemexpress LLC Tris (maleate) | 72200-76-1 | MFCD00082442 | 98.0% | 237.21 g·mol^-1 | C8H15NO7 | 50 G
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TRIS (maleate) is the maleate salt of tris(hydroxymethyl)aminomethane, supplied as a high-purity white crystalline powder for use as a buffering reagent in biological and biochemical research. It is commonly used to adjust pH and ionic strength in growth media, tissue preparations, and as a diluent or washing buffer; handle and store according to the product safety data sheet.
- High purity (98.0%) suitable for research use.
- Effective buffering capacity for biological media and assays.
- Compatible with growth media, tissue preparations, and washing steps.
- White crystalline powder form for accurate weighing and dissolution.
- Store sealed at 4°C; follow frozen storage recommendations for solutions.
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eMolecules 1588440-89-4 | 4-(Aminomethyl)-7-methoxy-3,4-dihydroquinolin-2(1H)-one hydrochloride | MFCD27920873 | 250mg
Ambeed | Dibenzo[bd]thiophene-2-carbaldehyde | 1g | 600827214 | A108182 | 22099-23-6 | MFCD02251670 | 212.270 | C13H8OS
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Medchemexpress LLC SODIUM DIACETATE 500G
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5000205838 SODIUM DIACETATE 500G
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Selleck Chemical LLC Chlorhexidine diacetate
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Chlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque
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