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Filtered Search Results
Selleck Chemical LLC GSK0660-5mg
GSK0660 is a potent PPARβ/δ antagonist with a pIC50 of 6.8 (binding assay IC50 = 155 nM; antagonist assay IC50 = 300 nM) and is nearly inactive on PPARα and PPARγ with IC50s above approximately 10 μM.
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Medchemexpress LLC CA-074 methyl ester | 147859-80-1 | MFCD00797532; MFCD03452890 | 397.47 g·mol⁻¹ | C19H31N3O6 | 1 ML
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CA-074 methyl ester is a membrane-permeable, selective inhibitor of the cysteine protease cathepsin B, used in vitro and in vivo to probe cathepsin B-related biology. It exhibits reported neuroprotective, anti-cancer, and anti-inflammatory activities, and is suitable for preparing concentrated DMSO stocks or formulated in multiple in vivo solvent systems.
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Medchemexpress LLC Oleanolic acid hemip | 50MG
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Oleanolic acid hemip | 50MG
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Medchemexpress LLC Z-WEHD-FMK | 210345-00-9 | 98.0% | 763.77 | 10 MG
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Z-WEHD-FMK is a potent, cell-permeable, and irreversible caspase-1/5 inhibitor. It also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6 μM) and can be used to investigate cells for evidence of apoptosis.
- Potent, cell-permeable and irreversible caspase-1/5 inhibitor
- Exhibits robust inhibitory effect on cathepsin B activity
- Can be used to investigate cells for evidence of apoptosis
- Elicits near-complete blockage of C. trachomatis-induced cleavage of golgin-84
- Inhibits E. piscicida-induced ZF4 cells cytotoxicity and pyroptotic morphology
- Significantly induces a decrease in IL-1β release in bone marrow-derived macrophages
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Selleck Chemical LLC Clopidogrel (SR-25990C) Bisulfate S1415-200mg
Clopidogrel (SR-25990C) Bisulfate is an oral thienopyridine class antiplatelet agent
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Medchemexpress LLC Silvestrol | 697235-38-4 | >98.0% | C34H38O13 | 10MG
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Silvestrol is a natural product isolated from Agave americana that inhibits eukaryotic translation initiation factor 4A (eIF4A) and is used as a research reagent to study translation regulation, autophagy, and apoptosis.
- Inhibits eIF4A-mediated translation.
- Induces autophagy and caspase-mediated apoptosis.
- Exhibits cytotoxic activity in human cancer cell lines.
- Supplied as a powder for research use.
- Purity >98.0%.
- Available in small pack sizes (1 mg-10 mg).
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
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Matrix Scientific METHYL 3,4-DIAMINOBENZOATE-5G
Methyl 3,4-diaminobenzoate, 5g,C8H10N2O2, MFCD00017098, mw 166.18, [36692-49-6]
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Chemscene ChemScene | Ethyl 2-methoxyacetate | 100G | CS-0008463 | 0.98 | 3938-96-3| MFCD00009176 | 118.13
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ChemScene | Ethyl 2-methoxyacetate | 100G | CS-0008463 | 0.98 | 3938-96-3| MFCD00009176 | 118.13
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eMolecules Methyl 3,5-diaminobenzoate | 1949-55-9 | MFCD00041433 | 1g
Combi-Blocks, Inc. | Methyl 3,5-diaminobenzoate | 1g | 569292570 | QF-6285 | 95.000 | 1949-55-9 | MFCD00041433 | 166.180 | C8H10N2O2
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eMolecules 1,5-Dimethyl-1H-pyrazole-3-carboxylic acid methyl ester | 10250-61-0 | 5G
Chem-Impex | 1,5-Dimethyl-1H-pyrazole-3-carboxylic acid methyl ester | 5G | 10250-61-0 | MFCD06659525 | MW:151.18
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Medchemexpress LLC ZXH-1-161 | 2407654-51-5 | 98.4% | 468.51 | 100 MG
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ZXH-1-161 is a potent CRBN modulator that selectively induces the degradation of GSPT1 in a CRBN-dependent manner. It can inhibit the proliferation of multiple myeloma cells and exhibits antitumor activity.
- Potent CRBN modulator.
- Selectively induces degradation of GSPT1.
- Inhibits proliferation of multiple myeloma cells.
- Exhibits antitumor activity.
- IC50 of 0.039 μM in MM1.S wild-type cells for antiproliferative activity.
- Induces GSPT1 degradation in MM1.S cells at 0.01-10 μM (4 h).
- Reduces GSPT1 levels in MM1.S cells in a dose-dependent manner.
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Medchemexpress LLC Episilvestrol | 697235-39-5 | MFCD25541744 | C34H38O13 | 1 MG
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Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia perviridis. It functions as a specific eIF4A-targeting translation inhibitor, demonstrating significant antitumor activity.
- Specific eIF4A-targeting translation inhibitor
- Exhibits antitumor activity
- Cytotoxic against human cancer cell lines including Lu1, LNCaP, MCF-7, and HUVEC
- Suppresses HK1 cells and EBV-positive C666.1 NPC cells
- Soluble in DMSO
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![eMolecules Medchem Express / TRPM8 antagonist 2 / 5mg / 437899175 / HY-112430 / / 259674-19-6 / [null] / 398.506 / C26H26N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502454827.PNG-250.jpg)
eMolecules Medchem Express / TRPM8 antagonist 2 / 5mg / 437899175 / HY-112430 / / 259674-19-6 / [null] / 398.506 / C26H26N2O2
Medchem Express / TRPM8 antagonist 2 / 5mg / 437899175 / HY-112430 / / 259674-19-6 / [null] / 398.506 / C26H26N2O2
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Chemscene ChemScene | Methyl 4-bromo-1H-pyrrole-2-carboxylate | 25G | CS-W007392 | 0.98 | 934-05-4| MFCD00832855 | 204.023
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ChemScene | Methyl 4-bromo-1H-pyrrole-2-carboxylate | 25G | CS-W007392 | 0.98 | 934-05-4| MFCD00832855 | 204.023
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Medchemexpress LLC Xanthinol Nicotinate | 437-74-1 | 99.9% | 500 MG
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Xanthinol Nicotinate, also known as Xanthinol Niacinate, is a vasodilator that directly affects the smooth muscle of small arteries and capillaries. It works by expanding blood vessels, which in turn improves blood rheology and reduces peripheral vascular resistance.
- Acts as a vasodilator.
- Directly acts on the smooth muscle of small arteries and capillaries.
- Expands blood vessels.
- Improves blood rheology.
- Reduces peripheral vascular resistance.
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