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Filtered Search Results
Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 ML
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Tegaserod maleate is an orally active serotonin receptor 4 (HTR4) agonist and a 5-HT2B receptor antagonist. It demonstrates anti-tumor activity by inducing tumor cell apoptosis and blunting PI3K/Akt/mTOR signaling. It is also being researched for its potential in treating irritable bowel syndrome (IBS) and diabetic gastropathy.
- Potent agonist of 5-HT4 receptor
- Antagonist of 5-HT2B receptor
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Accelerates gastric emptying rate
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Medchemexpress LLC (S)-Timolol maleate | 26921-17-5 | 99.8% | 432.49 | 50MG
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(S)-Timolol maleate is a non-cardioselective hydrophilic β-adrenoceptor blocker, commonly used as a standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. It can also be used for hypertension, angina pectoris, and myocardial infarction. As a chiral compound with one asymmetric carbon, the (S)-enantiomer is a non-cardioselective β-adrenergic blocker, with the (R)-isomer having lower biological activity.
- Non-cardioselective hydrophilic β-adrenoceptor blocker
- Used for intraocular pressure (glaucoma)
- Used for hypertension, angina pectoris, and myocardial infarction
- Single (S)-enantiomer
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Medchemexpress LLC BGT226 MALEATE 10MM 1ML
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BGT226 MALEATE 10MM 1ML
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Polysciences, Inc. 2-Hydroxyethyl methacrylate, Ophthalmic Grade
2-Hydroxyethyl methacrylate (HEMA) is perhaps the most widely studied and used neutral hydrophilic monomer. The monomer is soluble, its homopolymer is water-insoluble but plasticized and swollen in water. This monomer is the basis for many hydrogel products such as soft contact lenses, as well as polymer binders for controlled drug release, absorbants for body fluids and lubricious coatings. As a comonomer with other ester monomers, HEMA can be used to control hydrophobicity or introduce reactive sites.glycol methacrylateOpthalmic grade: Purity %=min. 99; Acid Content %=max 0.05; EGDMA content %=max 0.15; Color=30
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Medchemexpress LLC BGT226 MALEATE 1 mg
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BGT226 MALEATE 1MG
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eMolecules 27813-02-1 | 2-Hydroxypropyl methacrylate (mixture of 2-Hydroxypropyl and 2-Hydroxy-1-methylethyl Methacrylate) (stabilized with MEHQ) | Oakwood Chemical | MFCD00004536 | 144.170 | C7H12O3 | 95.000 | CC(O)COC(=O)C(C)=C | 1ml | 537717561
2-Hydroxypropyl methacrylate (mixture of 2-Hydroxypropyl and 2-Hydroxy-1-methylethyl Methacrylate) (stabilized with MEHQ) | Oakwood Chemical | 27813-02-1 | MFCD00004536 | 144.170 | C7H12O3 | 95.000 | CC(O)COC(=O)C(C)=C | 1ml | 537717561
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eMolecules 18305-60-7 | AstaTech | DI-TERT-BUTYL MALEATE | 0.25g | 233620211 | 26264 | 95 | MFCD23381095 | 228.288 | C12H20O4
Ambeed | N-(3-Chloropropyl)-4-(4455-tetramethyl-132-dioxaborolan-2-yl)benzamide | 1g | 714084318 | A1543861 | 2828443-90-7 | 323.620 | C16H23BClNO3
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Medchemexpress LLC BGT226 MALEATE 50 mg
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BGT226 MALEATE 50MG
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Medchemexpress LLC U-99194 maleate | 234757-41-6 | MFCD01529985 | 99.2% | 393.47 g/mol | C21H31NO6 | 5 MG
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U-99194 maleate is a selective dopamine D3 receptor antagonist supplied as the maleate salt for research use. It is commonly used to probe D3-mediated signaling and motor disorder models, and is offered in small, research-sized quantities with reported high purity for biochemical and pharmacological studies.
- Selective dopamine D3 receptor antagonist useful for receptor pharmacology studies.
- Supplied as the maleate salt for stability and handling.
- High reported purity (99.2%) suitable for biochemical assays.
- Available in small milligram pack sizes for preclinical research.
- Characterized by molecular formula C21H31NO6 and molecular weight 393.47 g/mol.
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Chemscene CHEMSCENE
5000580079 DIETHYL MALEATE 500G
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Cayman Chemical Thioperamide (maleate), Purity: ≥98%, CAS: 148440-81-7, 1 mg
A histamine H3 receptor antagonist (Ki = 4.3 nM); selective for the histamine H3 receptor over histamine H1 and H2 receptors (Kis = >10,000 nM for both) and a panel of 36 other receptors and ion channels; has anticonvulsant activity, reverses immepip-induced antinociception, and promotes wakefulness in rats; decreases cognitive impairments in APP/PS1 mice
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Medchemexpress LLC Vicriviroc maleate | 599179-03-0 | MFCD09833218 | 99.9% | 649.70 | 1 ML
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Vicriviroc maleate is a potent, selective, and orally bioavailable CCR5 antagonist. It is CNS penetrated with a Ki of 2.5 nM. This compound effectively inhibits HIV-1 in PBMC cells across various strains.
- Potent and selective CCR5 antagonist
- Oral bioavailable and CNS penetrated
- Inhibits HIV-1 in PBMC cells
- Active against multiple HIV-1 strains
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Medchemexpress LLC 4-PPBP maleate | 201216-39-9 | 99.6% | 409.52 g/mol | C25H31NO4 | 50 MG
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4-PPBP maleate is a research-grade sigma-1 (σ1) receptor ligand and agonist used in neuroscience studies. It acts as a non-competitive, selective antagonist of NR1a/2B NMDA receptors and has been used in models of neuroprotection. The compound is supplied as a solid with high reported purity and defined storage recommendations for stability.
- Potent sigma-1 receptor ligand and agonist.
- Non-competitive, selective NR1a/2B NMDA receptor antagonist.
- Used in neuroprotection research models.
- High purity (99.6%).
- Supplied as a solid for convenient handling.
- Stable when stored sealed at 4°C; solvent storage conditions applicable.
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Medchemexpress LLC PD-168077 maleate | 630117-19-0 | 99.6% | 450.49 | 100 MG
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PD-168077 maleate is a selective dopamine D4 receptor agonist with a Ki of 9 nM. It is for research use only. It shows high selectivity over other D2-like receptor family members and D1-like counterparts, as well as α1, α2, 5-HT1A, and 5-HT2A receptors. It evidences intrinsic activity at the D4 receptor and can induce locomotion in a dose-dependent manner. This product may be used in research related to neurological diseases, neurodegenerative diseases, depression, and Parkinson's disease.
- Selective dopamine D4 receptor agonist
- High selectivity over other receptor types
- Evidences intrinsic activity at the D4 receptor
- Induces locomotion in PD-168077-treated cells
- May be used in research for neurological diseases
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Medchemexpress LLC Avitinib maleate | 1557268-88-8 | 99.9% | 603.60 | 100 MG
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Avitinib (Abivertinib) maleate is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M and wild-type EGFR. Avitinib maleate is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib maleate shows anticancer effects.
- Third-generation, irreversible and orally active selective EGFR inhibitor.
- Potent inhibition of EGFR L858R (IC50: 0.18 nM), EGFR T790M (IC50: 0.18 nM), and wild-type EGFR (IC50: 7.68 nM).
- BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma.
- Exhibits anticancer effects.
- Selectively inhibits mutant EGFR phosphorylation.
- Inhibits phosphorylation of downstream targets Akt and ERK1/2 in NCI-H1975 and HCC827 cells.
- Inhibits EGFR-mutant tumor growth in xenograft models over extended duration.
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