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Filtered Search Results
Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MM 1 ML
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Asenapine maleate (Org 5222 maleate) is a brain-penetrant atypical antipsychotic. It acts as an antagonist for serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This compound is utilized in research for conditions such as schizophrenia and bipolar disorder.
- Antagonist of serotonin, adrenoceptors, dopamine, and histamine receptors.
- Brain-penetrant atypical antipsychotic.
- Used in schizophrenia and bipolar disorder research.
- Higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B and D3 receptors relative to D2.
- May offer superior therapeutic effects on anxiety.
- Demonstrates anxiolytic-like effects in animal models.
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 5mg
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NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g·mol-1 | C18H24N2O4 | 10 MG
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Cipralisant maleate is a research-grade histamine H3 receptor antagonist supplied as the maleate salt. It is used in pharmacology and neuroscience studies to probe H3 receptor activity and related signaling pathways. Provided as a solid with high reported purity, this compound is for laboratory research use only and not for human or veterinary applications.
- Orally active histamine H3 receptor antagonist for research applications.
- High purity (99.8%).
- White to off-white solid appearance.
- Soluble in DMSO (≥ 100 mg/mL).
- Molecular weight 332.39 g·mol-1; formula C18H24N2O4.
- Stable as powder at -20°C for long-term storage; in solution store at -80°C.
- Supplied in small laboratory-scale quantities suitable for preclinical studies.
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Medchemexpress LLC Zamifenacin fumarate | 127308-98-9 | MFCD09263617 | 99.0% | 531.60 g/mol | C31H33NO7 | 100 MG
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Zamifenacin fumarate is a synthetic small molecule and gut-selective muscarinic M3 receptor antagonist used in pharmacological research to study gastrointestinal motility. It has been shown to reduce colonic motility in preclinical studies. The fumarate salt has formula C31H33NO7, molecular weight 531.60 g/mol, CAS 127308-98-9, and is supplied at high purity for research applications.
- Selective muscarinic M3 receptor antagonism.
- Gut-selective activity that minimizes systemic muscarinic effects.
- Demonstrated reduction of colonic motility in preclinical models.
- Supplied as the fumarate salt with molecular formula C31H33NO7.
- High purity suitable for research use (99.0%).
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Selleck Chemical LLC Perhexiline maleate
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Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 M and 148 M for rat heart CPT1 and liver CPT1 respectively and also inhibits carnitine palmitoyltransferase 2 (CPT2)
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eMolecules 1785665-61-3 | Medchem Express | VUF11207 (fumarate) | 5mg | 515743918 | HY-110318 | MFCD27991278 | 586.657 | C31H39FN2O8
ChemScene | Methyl 4-amino-35-dichloro-2-fluorobenzoate | 100mg | 746310752 | CS-0612352 | 2649788-83-8 | 238.040 | C8H6Cl2FNO2
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Medchemexpress LLC Betrixaban maleate | 936539-80-9 | MFCD16038040 | 99.8% | 567.98 | C27H26ClN5O7 | 10 MG
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Betrixaban maleate is the maleate salt of betrixaban, a potent and selective orally efficacious factor Xa (fXa) inhibitor with an IC50 of 1.5 nM. Supplied as a solid for research use, it demonstrates antithrombotic activity and includes specified purity, storage, and solubility data for laboratory handling.
- High purity (99.8%).
- White to off-white solid form.
- Molecular weight 567.98 g/mol.
- CAS number 936539-80-9.
- Soluble in DMSO (50 mg/mL) and in water (2 mg/mL) with warming and sonication.
- Storage: 4°C sealed; in solvent -80°C (6 months), -20°C (1 month).
- Provided as a 10 MG research pack.
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Medchemexpress LLC Ilginatinib maleate | 1239358-86-1 | MFCD28502056 | 99.9% | 389.43 | C21H20FN7 | 10 MG
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Ilginatinib maleate is an orally bioavailable small-molecule JAK2 inhibitor supplied as the maleate salt for laboratory research. It shows sub-nanomolar potency against JAK2 with a selective profile over related kinases, and is provided as a powder with documented solubility and storage guidance for experimental use.
- Highly potent JAK2 inhibition (IC50 0.72 nM).
- Demonstrates selectivity versus JAK1, JAK3, and Tyk2.
- Supplied as a powder suitable for laboratory preparation.
- High chemical purity (≈99.9%).
- Soluble in DMSO at 100 mg/mL for stock solutions.
- Storage and stability data provided for powder and solutions.
- Intended for research use only; not for clinical or human use.
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eMolecules 18162-82-8 | Chloromethyltriisopropoxysilane | Ambeed | MFCD05664343 | 254.830 | C10H23ClO3Si | 96.000 | CC(C)O[Si](CCl)(OC(C)C)OC(C)C | 1g | 521471713
Chloromethyltriisopropoxysilane | Ambeed | 18162-82-8 | MFCD05664343 | 254.830 | C10H23ClO3Si | 96.000 | CC(C)O[Si](CCl)(OC(C)C)OC(C)C | 1g | 521471713
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eMolecules 130561-48-7 | AstaTech | 3-CINNOLINECARBOXYLIC ACID 1-(4-CHLOROPHENYL)-14-DIHYDRO-5-(2-METHOXYETHOXY)-4-OXO- | 0.25g | 448268141 | A12000 | 95 | MFCD28556890 | 374.78 | C18H15ClN2O5
Pharmablock | 6-methoxy-5-nitro-1H-indazole | 25mg | 788496058 | PBDW003 | 152626-75-0 | MFCD11007881 | 193.162 | C8H7N3O3
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Pfaltz & Bauer DIMETHYL MALEATE 99% 250G
Dimethyl maleate 99%; 250G CAS# 624-48-6
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Selleck Chemical LLC Rosiglitazone maleate S2505-10mM/1mL
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Rosiglitazone maleate a member of the thiazolidinedione class of antihyperglycaemic agents is a high-affinity selective agonist of the peroxisome proliferator-activated receptor- (PPAR- ) with IC50 of 42 nM Rosiglitazone maleate also modulates TRP channels and induces autophagy Rosiglitazone prevents ferroptosis
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Medchemexpress LLC Indacaterol maleate (standard) | 753498-25-8 | 99.6% | C28H32N2O7 | 100 MG
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Indacaterol maleate (standard) | 753498-25-8 | 99.6% | C28H32N2O7 | 100 MG
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eMolecules 37526-88-8 | Benzyl tiglate stabilized with 0.1% alpha-tocopherol | Oakwood Chemical | MFCD00017279 | 190.242 | C12H14O2 | 0.000 | C\C=C(/C)C(=O)OCc1ccccc1 | 1g | 537710580
Benzyl tiglate stabilized with 0.1% alpha-tocopherol | Oakwood Chemical | 37526-88-8 | MFCD00017279 | 190.242 | C12H14O2 | 0.000 | C\C=C(/C)C(=O)OCc1ccccc1 | 1g | 537710580
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Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | 99.7% | 673.11 | 5 MG
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Neratinib maleate is an orally available, irreversible, and highly selective inhibitor of HER2 and EGFR. It effectively inhibits the proliferation of cell lines expressing high levels of HER-2 and shows anticancer activities in tumor xenograft models. This compound induces G1-S phase arrest and leads to inhibition of MAPK and Akt phosphorylation.
- Orally available
- Irreversible, highly selective HER2 and EGFR inhibitor
- Inhibits proliferation of HER-2 expressing cell lines
- Induces G1-S phase arrest
- Inhibits MAPK and Akt phosphorylation
- Shows anticancer activity in tumor xenograft models
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