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Filtered Search Results
Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.1% | 172.18 g/mol | C8H12O4 | 500mg
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Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]
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![eMolecules Synthonix / methyl 1-amino-6-bromoisoquinoline-4-carboxylate / 250mg / 779537019 / AC78107 / / 2090332-56-0 / [null] / 281.109 / C11H9BrN2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502478617.JPG-250.jpg)
eMolecules Synthonix / methyl 1-amino-6-bromoisoquinoline-4-carboxylate / 250mg / 779537019 / AC78107 / / 2090332-56-0 / [null] / 281.109 / C11H9BrN2O2
Synthonix / methyl 1-amino-6-bromoisoquinoline-4-carboxylate / 250mg / 779537019 / AC78107 / / 2090332-56-0 / [null] / 281.109 / C11H9BrN2O2
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eMolecules Harringtonine | 26833-85-2 | MFCD28978177 | 250mg
Combi-Blocks, Inc. | Harringtonine | 250mg | 603142371 | HD-9179 | 95.000 | 26833-85-2 | MFCD28978177 | 531.602 | C28H37NO9
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Medchemexpress LLC Quipazine maleate | 5786-68-5 | >98% | 50 MG
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Quipazine maleate is a 5-HT agonist that causes behavioral changes such as hyperactivity. It also shows a weak reversible MAO inhibitory activity. This piperazine-based nonselective serotonin receptor agonist targets several 5-HT receptor subtypes, including 5-HT₂A (pKi ≈ 6.9), 5-HT₂C (≈ 7.27), and 5-HT₂B, as well as showing marked agonist activity at 5-HT₃ (EC₅₀ ≈ 1.0 nM). It has been explored for anti-parkinsonian potential in preclinical settings and is a valuable pharmacological tool for studying serotonin receptor functions.
- 5-HT agonist
- Causes behavioral changes such as hyperactivity
- Weak reversible MAO inhibitory activity
- Nonselective serotonin receptor agonist
- Targets 5-HT₂A, 5-HT₂C, 5-HT₂B, and 5-HT₃ receptors
- Explored for anti-parkinsonian potential
- Valuable pharmacological tool for studying serotonin receptor functions
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TARGETMOL CHEMICALS INC DIZOCILPINE MALEATE 50MG
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Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. purity: 99%
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Medchemexpress LLC DBM-MMAF | 1810001-93-4 | 99.7% | 1082.95 g/mol | C49H74Br2N6O11 | 50 MG
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DBM-MMAF is a drug-linker conjugate used to construct antibody-drug conjugates (ADCs). It links the potent antitubulin payload monomethyl auristatin F (MMAF) to a DBM linker, enabling targeted delivery of cytotoxic agents for research and in vitro evaluation.
- Drug-linker conjugate for ADC synthesis and evaluation.
- Contains monomethyl auristatin F (MMAF) payload.
- High purity (99.65%) and chemical formula C49H74Br2N6O11.
- Soluble in DMSO; store protected from light at 4°C (in solvent: -80°C up to 6 months).
- Provided as a 50 mg quantity for research use.
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Medchemexpress LLC Perhexiline maleate | 6724-53-4 | MFCD00057329 | 98.0% | 393.56 | C23H39NO4 | 10 MG
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Perhexiline maleate is the maleate salt of perhexiline, a small-molecule inhibitor of carnitine palmitoyltransferase 1 and 2 (CPT1/CPT2) used in preclinical research to probe mitochondrial fatty-acid metabolism, cancer biology, and cardiovascular disease models. It is provided as a solid salt intended for biochemical and cell-based assays.
- Inhibits CPT1 and CPT2, reducing fatty-acid oxidation
- Maleate salt form improves aqueous handling for assays
- Available in research-scale quantities, including 10 mg
- High reported purity suitable for in vitro and preclinical studies
- Documented chemical identifiers include CAS 6724-53-4 and molecular weight 393.56
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eMolecules 2-Hydroxypropyl methacrylate (mixture of 2-Hydroxypropyl and 2-Hydroxy-1-methylethyl Methacrylate) (stabilized with MEHQ) | 27813-02-1 | MFCD00004536 | 1ml
Oakwood Chemical | 2-Hydroxypropyl methacrylate (mixture of 2-Hydroxypropyl and 2-Hydroxy-1-methylethyl Methacrylate) (stabilized with MEHQ) | 1ml | 537717561 | 235572 | | 27813-02-1 | MFCD00004536 | 144.170 | C7H12O3
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Apexbio Technology LLC (S)-(+)-Dimethindene maleate(Synonyms: (+)-Dimethindene maleate, Dexdimethindene maleate, (S)-Dimetindene maleate, (S)-(+)-Dimetindene maleate), 50mg, CAS: 136152-65-3.
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(S)-( )-Dimethindene maleate (CAS 136152-65-3) is a small molecule antagonist exhibiting selective affinity for the muscarinic acetylcholine receptor subtype M2 while showing comparatively reduced interaction with M1 M3 and M4 subtypes Additionally it acts as an antagonist at histamine H1 receptors Due to its receptor selectivity profiles it is employed in pharmacological studies investigating autonomic regulation mechanisms cardiovascular physiology and respiratory system function
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eMolecules Ethyl 4-nitrocinnamate | 953-26-4 | MFCD00007380 | 5g
Oakwood Chemical | Ethyl 4-nitrocinnamate | 5g | 537664091 | 002995 | | 953-26-4 | MFCD00007380 | 221.212 | C11H11NO4
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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.8% | C28H32N2O7 | 1 ML
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Indacaterol maleate is an orally active, ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. It functions by inhibiting NF-κB activity in a β-arrestin2-dependent manner. This chemical property contributes to preventing further lung damage and improving lung function in conditions like chronic obstructive pulmonary disorder (COPD). It also has potential applications in cardiovascular disease research.
- Acts as an ultra-long-acting β2 adrenergic receptor (ADRB2) agonist.
- Inhibits NF-κB activity via a β-arrestin2-dependent mechanism.
- Suppresses MMP-9 mRNA expression and activity.
- Reduces cell migration and inhibits NF-κB nuclear translocation.
- Active in normalizing cardiac remodeling in heart failure models.
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Medchemexpress LLC Ethynodiol diacetate | 297-76-7 | 99.9% | 1 ML
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Ethynodiol diacetate is a click chemistry reagent that contains an Alkyne group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Features and benefits:
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules containing azide groups
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eMolecules Ambeed Benzyl propiolate 100mg 784395629 A332728 0 000 14447-01-9 MFCD11976128 160 172 C10H8O2
Ambeed Benzyl propiolate 100mg 784395629 A332728 0 000 14447-01-9 MFCD11976128 160 172 C10H8O2
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Medchemexpress LLC Ciproxifan (maleate) | 184025-19-2 | MFCD06411563 | 99.7% | 386.40 g/mol | C20H22N2O6 | 10 MG
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Ciproxifan maleate is a potent, selective, orally bioavailable competitive antagonist of the histamine H3 receptor supplied as a white to off-white powder for research use. It is used as an analytical standard and research reagent in neuroscience and aging-disease studies, with reported nanomolar potency.
- Potent H3 receptor antagonist (IC50 ≈ 9.2 nM)
- High purity (≈ 99.7%)
- Provided as a powdered maleate salt for stability and handling
- Suitable for neuroscience and Alzheimer's disease research
- Available in small pack sizes for analytical and screening use
- Includes CAS number 184025-19-2 and molecular weight 386.40 g/mol
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Medchemexpress LLC Cinepazide Maleate | 26328-04-1 | 99.7% | C26H35N3O9 | 25 MG
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Cinepazide Maleate is a piperazine derivative that acts as a weak calcium channel blocker and a potent vasodilator. It is utilized in research for cerebrovascular diseases, including ischemic stroke and brain infarct.
- Acts as a weak calcium channel blocker
- Potent vasodilator
- Used for research on cerebrovascular diseases
- Suitable for ischemic stroke and brain infarct research
- For research use only
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