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Filtered Search Results
eMolecules Ethyl propiolate | Combi-Blocks | 623-47-2 | MFCD00009184 | 98.101 | C5H6O2 | 98.000 | CCOC(=O)C#C | 25g | 249355929
Ethyl propiolate | Combi-Blocks | 623-47-2 | MFCD00009184 | 98.101 | C5H6O2 | 98.000 | CCOC(=O)C#C | 25g | 249355929
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eMolecules Medchem Express / Z-DEVD-FMK / 1mg / 446261296 / HY-12466 / / 210344-95-9 / MFCD23380217 / 668.672 / C30H41FN4O12
Medchem Express / Z-DEVD-FMK / 1mg / 446261296 / HY-12466 / / 210344-95-9 / MFCD23380217 / 668.672 / C30H41FN4O12
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![Medchemexpress LLC 8-Quinolinol, 7-[(3-ethoxy-4-methoxyphenyl)[(4-methyl-2-pyridinyl)amino]methyl]- | 430462-93-4 | 98.1% | 415.48 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000388173-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 8-Quinolinol, 7-[(3-ethoxy-4-methoxyphenyl)[(4-methyl-2-pyridinyl)amino]methyl]- | 430462-93-4 | 98.1% | 415.48 | 50 MG
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HQ-415 is a biologically active metal chelator demonstrating an EC50 of 15 μM. This compound is structurally related to Clioquinol and appears as a solid with a white to off-white color. It is intended for research use only.
- Biologically active.
- Acts as a metal chelator.
- Has an EC50 of 15 μM.
- Provided as a solid.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378539 PTP1B-IN-4 5MG
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Medchemexpress LLC Dizocilpine maleate | 77086-22-7 | C20H19NO4 | 25 MG
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Dizocilpine maleate (MK-801 maleate) is a potent, selective, and non-competitive NMDA receptor antagonist. It effectively blocks N-Me-D-Asp-induced current and inhibits microglial activation, reducing TNF-α output. This compound is also utilized for inducing schizophrenia models in rats.
- Potent, selective, and non-competitive NMDA receptor antagonist
- Blocks current induced by N-Me-D-Asp
- Inhibits activation of microglia induced by LPS
- Reduces microglial TNF-α output
- Used to induce schizophrenia models in rats
- Cited in over 40 publications
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Selleck Chemical LLC Vicriviroc maleate S3494-25mg
Vicriviroc maleate(SCH-417690 maleate SCH-D maleate) is a potent selective oral bioavailable and CNS penetrated antagonist of CCR5 with a Ki of 2 5 nM and also inhibits HIV-1 in PBMC cells
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Chem-Impex International, Inc. Methyl 3-cyanobenzoate | 13531-48-1 | MFCD00220156 | 25G
Methyl 3-cyanobenzoate, 13531-48-1, MFCD00220156, 25G
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Medchemexpress LLC Velnacrine maleate | 118909-22-1 | 98.0% | 330.34 | 25 MG
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Velnacrine maleate (HP 029) is an orally active cholinesterase inhibitor used in the research of Alzheimer's disease. It is a solid appearing from light yellow to khaki color, and it is soluble in DMSO. This compound is provided with comprehensive data including a datasheet, COA, and SDS.
- Orally active cholinesterase inhibitor
- Can be used for Alzheimer's disease research
- Comprehensive documentation including datasheet, COA, and SDS
- Provided as a solid with color ranging from light yellow to khaki
- Soluble in DMSO
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Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MM 1 ML
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Asenapine maleate (Org 5222 maleate) is a brain-penetrant atypical antipsychotic. It acts as an antagonist for serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4), and histamine receptors (pKi: 8.2-9.0). This compound is utilized in research for conditions such as schizophrenia and bipolar disorder.
- Antagonist of serotonin, adrenoceptors, dopamine, and histamine receptors.
- Brain-penetrant atypical antipsychotic.
- Used in schizophrenia and bipolar disorder research.
- Higher affinity for 5-HT2C, 5-HT2A, 5-HT2B, 5-HT7, 5-HT6, α2B and D3 receptors relative to D2.
- May offer superior therapeutic effects on anxiety.
- Demonstrates anxiolytic-like effects in animal models.
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Medchemexpress LLC SODIUM DIACETATE 500G
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5000205838 SODIUM DIACETATE 500G
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Medchemexpress LLC Avitinib maleate | 1557268-88-8 | MFCD29089376 | 99.9% | 603.60 | C30H30FN7O6 | 10 MG
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Avitinib maleate is a third-generation, irreversible, orally active EGFR inhibitor supplied as the maleate salt for research use. It exhibits potent activity against EGFR L858R and T790M mutations, with reported BTK inhibitory activity, and is provided with analytical data confirming high purity. Typical formats include small solid quantities and DMSO solutions for laboratory studies.
- Third-generation, irreversible EGFR inhibitor suitable for targeted research.
- Potent activity against EGFR L858R and T790M mutants.
- Reduced potency against wild-type EGFR to aid selectivity studies.
- Maleate salt form for improved handling and stability.
- High purity with RP-HPLC documentation.
- Available in small solid pack sizes and solution formats for assays.
- Intended for in vitro and preclinical research applications.
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Medchemexpress LLC Ro 25-6981 Maleate | 1312991-76-6 | 99.25% | 455.54 | 100 MG
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Ro 25-6981 Maleate is a potent, selective, and activity-dependent NR2B subunit-specific NMDA receptor antagonist. It demonstrates anticonvulsant and anti-parkinsonian activity and has potential for research into Parkinson's disease.
- Potent, selective, and activity-dependent NR2B subunit-specific NMDA receptor antagonist
- Demonstrates anticonvulsant activity
- Demonstrates anti-parkinsonian activity
- Potential for Parkinson's disease research
- Induces contraversive rotations in 6-OHDA-lesioned rats
- Exhibits age- and activation-dependent anticonvulsant action
- Shows analgesic effects on incision pain in rats
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Medchemexpress LLC Trimebutine (maleate) | 34140-59-5 | 99.66% | 5 G
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Trimebutine (maleate) | 34140-59-5 | 99.66% | 5 G
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Apexbio Technology LLC CA 074 134448-10-5 10mg
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CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
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Medchemexpress LLC HY-50904 1g , BIBF 1120 Nintedanib CAS:656247-17-5 Purity:98%
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Medchemexpress, HY-50904 1g BIBF 1120 Nintedanib CAS:656247-17-5 Formula:C31H33N5O4 IC50: 34 nM (VEGFR1), 13 nM (VEGFR2), 13 nM (VEGFR3), 69 nM (FGFR1), 37 nM (FGFR1), 108 nM (FGFR1), 59 nM (PDGFRα), 65 nM (PDGFRβ) Purity:98% BIBF 1120 is a potent triple angiokinase inhibitor for VEGFR1/2/3 , FGFR1/2/3 and PDGFRα/β with IC 50 s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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