Dicarboxylic acids and derivatives
Medchemexpress LLC Lauroyl coenzyme A (lithium) | 190063-12-8 | 99% | 1 MG
Lauroyl coenzyme A lithium salt is an intermediary in fatty acid synthesis or metabolism. It is formed by combining long-chain fatty acids (specifically lauric acid) with coenzyme A. This compound plays a role in lipid biosynthesis and fatty acid transport, where coenzyme A acts as a transport molecule to facilitate the movement and targeting of specific compounds.
- Intermediary in fatty acid synthesis or metabolism.
- Formed by combining long-chain fatty acids (lauric acid) with coenzyme A.
- Involved in lipid biosynthesis and fatty acid transport.
- Coenzyme A acts as a transport molecule to help move and target specific compounds.
- Purity: 99%.
- Appearance: White to off-white solid.
Medchemexpress LLC RG-101 sodium | 00-00-0 | 95.4% | 8537.6 (free acid) | C295H410N78Na19O146P19S17 | 5 MG
RG-101 sodium is a hepatocyte-targeted N-acetylgalactosamine (GalNAc)-conjugated antisense oligonucleotide that antagonizes microRNA-122 (miR-122), a host factor important for hepatitis C virus replication. Supplied as a sodium salt, it is used in research to study miR-122 biology and antiviral mechanisms.
- Hepatocyte-targeted GalNAc conjugate for liver delivery.
- Antagonizes miR-122 to modulate hepatitis C virus-related pathways.
- High molecular weight oligonucleotide for sequence-specific activity.
- High purity (95.4%) suitable for research applications.
- Soluble in water; sonication may be required for dissolution.
- Recommended storage at -20°C; in solution store at -80°C for long-term.
Medchemexpress LLC UCPH-101 | 1118460-77-7 | 98.6% | 422.48 | 50 MG
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. It demonstrates cellular effects on HEK293 cells by inhibiting human EAAT1. This product is for research use only.
- Acts as an EAAT1 inhibitor
- Demonstrates cellular effects on HEK293 cells
- Inhibits human EAAT1 anion currents
Medchemexpress LLC Rhodamine 101 hydrochloride | 64339-18-0 | MFCD00210089 | >=95% | 563.51 | 5 MG
Rhodamine 101 chloride (Rhodamine 640 chloride) hydrochloride is a bright fluorescent dye with excitation and emission maxima of 565 and 595 nm, respectively.
- For research use only.
- We do not sell to patients.
Medchemexpress LLC MZ-101 (GYS1-IN-2) | 2839908-40-4 | 99.0% | 449.52 | C25H28FN5O2 | 10 MG
MZ-101 (GYS1-IN-2) is an orally active, potent, and selective small-molecule inhibitor of glycogen synthase 1 (GYS1) with an IC50 of 0.041 μM. It reduces glycogen concentrations in cells and in mice and is used to study GYS1-mediated Pompe disease and other glycogen storage disorders.
- Potent, selective GYS1 inhibition (IC50 = 0.041 μM).
- Reduces glycogen concentrations in cells and animal models.
- Orally active small molecule suitable for in vivo studies.
- High purity (98.98%) and solid physical form for storage stability.
- Available in small solid quantities and DMSO solutions for flexible dosing.
- Storage: powder stable at -20 °C (up to three years) and 4 °C (up to two years).
Medchemexpress LLC BNC-101 5mg | 5mg
BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)
Medchemexpress LLC BNC-101 10mg | 10mg
BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5 The predicted molecular weight (MW) of BNC-101 is 150 kDa The isotype control for BNC-101 can refer to Human IgG1 kappa Isotype Control (HY-P99001)
![Medchemexpress LLC Tetradecanoic acid, 2,3-bis[(1-oxododecyl)oxy]propyl ester | 60175-30-6 | MFCD00063570 | 98.0% | 667.05 g/mol | C41H78O6 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000288249.png-250.jpg)
Medchemexpress LLC Tetradecanoic acid, 2,3-bis[(1-oxododecyl)oxy]propyl ester | 60175-30-6 | MFCD00063570 | 98.0% | 667.05 g/mol | C41H78O6 | 10 MG
1,2-Dilauroyl-3-myristoyl-rac-glycerol is a medium-chain triacylglycerol used as a research reagent and an intermediate for synthesizing functional edible oils and related lipid derivatives. It is typically supplied in small, research-scale quantities for laboratory studies.
- Medium-chain triacylglycerol suitable for lipid synthesis and formulation.
- High purity (98.0%) suitable for research applications.
- Chemical formula C41H78O6; molecular weight 667.05 g/mol.
- Appearance: white to off-white oil.
- Provided in small research-scale quantities (e.g., 10 mg).
Medchemexpress LLC VNT-101 | 2894060-67-2 | 99.5% | 456.41 | 5 MG
VNT-101 is an orally active influenza A (IAV) inhibitor that disrupts NP-NP PPI to block NP oligomerization and destabilize the viral ribonucleoprotein (RNP) complex. It exhibits potent antiviral activity across multiple influenza A subtypes and robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus. It can be used for the study of influenza A infection.
- Orally active influenza A (IAV) inhibitor.
- Disrupts NP-NP PPI to block NP oligomerization.
- Destabilizes the viral ribonucleoprotein (RNP) complex.
- Potent antiviral activity across multiple influenza A subtypes.
- Exhibits EC50 values of 4-5 nM in cellular cytopathic effect (CPE) assay, 4-8 nM in neuraminidase (NA) assay, and 21-45 nM in RNP assay.
- Demonstrates robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus.
Apexbio Technology LLC LOXO-101 1223405-08-0 5mg
LOXO-101 (CAS 1223405-08-0) is a potent and selective inhibitor of the tropomyosin receptor kinase (TRK) family demonstrating low nanomolar inhibitory activity across all TRK isoforms LOXO-101 disrupts signaling mediated by neurotrophin receptors which are critical for neuronal development and survival In kinase profiling LOXO-101 exhibited minimal off-target activity with significant inhibition observed only for TNK2 (IC50 576 nM) and did not display hERG inhibition or QT prolongation effects In vivo studies revealed dose-dependent tumor growth suppression in xenograft models Clinically LOXO-101 has been evaluated for safety and pharmacokinetics and induced rapid tumor regression in a TRK fusion-positive patient highlighting its utility in studying TRK-driven malignancies
Apexbio Technology LLC AS 101 106566-58-9 50mg
AS 101 (CAS 106566-58-9) chemically known as ammonium trichloro(dioxoethylene-O O -)tellurate is a non-toxic immunomodulatory small molecule that acts primarily by inhibiting interleukin-10 (IL-10) signaling In cell-based studies AS 101 reduces IL-10 production and suppresses mesangial cell proliferation in a dose-dependent manner It has been shown to decrease tyrosine phosphorylation and nuclear translocation of STAT3 correlating with inhibition of IL-10 activity AS 101 stimulates IL-2 secretion and enhances immune cell function in both human and murine models In animal studies systemic administration confers bone marrow-sparing effects during chemotherapy mitigates alopecia enhances survival in sepsis models and modulates cytokine production These properties support its utility in investigating immune regulation and potential therapeutic interventions targeting cytokine-mediated pathologies