Dicarboxylic acids and derivatives
Selleck Chemical LLC GlyH-101
GlyH-101 is a selective and reversible CFTR inhibitor with Ki of 4 3 M
Apexbio Technology LLC PKUMDL-LC-101-D04 2143896-83-5 5mg
PKUMDL-LC-101-D04 (CAS 2143896-83-5) is a small molecule allosteric activator of glutathione peroxidase 4 (GPX4) a key enzyme regulating ferroptosis In biochemical and cell extract assays PKUMDL-LC-101-D04 enhances GPX4 activity to 150% of baseline at concentrations of 20 M and 61 M respectively This compound serves as a valuable tool for investigating the modulation of ferroptosis through GPX4 activation and supports research into oxidative stress and cell death mechanisms
Apexbio Technology LLC AS 101 106566-58-9 50mg
AS 101 (CAS 106566-58-9) chemically known as ammonium trichloro(dioxoethylene-O O -)tellurate is a non-toxic immunomodulatory small molecule that acts primarily by inhibiting interleukin-10 (IL-10) signaling In cell-based studies AS 101 reduces IL-10 production and suppresses mesangial cell proliferation in a dose-dependent manner It has been shown to decrease tyrosine phosphorylation and nuclear translocation of STAT3 correlating with inhibition of IL-10 activity AS 101 stimulates IL-2 secretion and enhances immune cell function in both human and murine models In animal studies systemic administration confers bone marrow-sparing effects during chemotherapy mitigates alopecia enhances survival in sepsis models and modulates cytokine production These properties support its utility in investigating immune regulation and potential therapeutic interventions targeting cytokine-mediated pathologies
Medchemexpress LLC AVN-101 hydrochlorid 25mg | 1061354-48-0 | 340.89 | C21H25ClN2 | 25 MG
AVN-101 hydrochloride is the hydrochloride salt of a brain-penetrant small molecule antagonist of serotonin (5-HT) receptors, supplied for preclinical and in-vitro research. It is provided as a solid with reported high purity for analytical and biological assays.
- Potent antagonist of 5-HT receptor subtypes (5-HT7, 5-HT6, 5-HT2A, 5-HT2C).
- High purity: 99.59%.
- Molecular formula C21H25ClN2; molecular weight 340.89.
- Available in small research pack sizes, including 25 MG.
- Provided as hydrochloride salt to improve solubility for assay preparation.
- For research use only; not for human or veterinary use.
![Medchemexpress LLC Tetradecanoic acid, 2,3-bis[(1-oxododecyl)oxy]propyl ester | 60175-30-6 | MFCD00063570 | 98.0% | 667.05 g/mol | C41H78O6 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000288249.png-250.jpg)
Medchemexpress LLC Tetradecanoic acid, 2,3-bis[(1-oxododecyl)oxy]propyl ester | 60175-30-6 | MFCD00063570 | 98.0% | 667.05 g/mol | C41H78O6 | 10 MG
1,2-Dilauroyl-3-myristoyl-rac-glycerol is a medium-chain triacylglycerol used as a research reagent and an intermediate for synthesizing functional edible oils and related lipid derivatives. It is typically supplied in small, research-scale quantities for laboratory studies.
- Medium-chain triacylglycerol suitable for lipid synthesis and formulation.
- High purity (98.0%) suitable for research applications.
- Chemical formula C41H78O6; molecular weight 667.05 g/mol.
- Appearance: white to off-white oil.
- Provided in small research-scale quantities (e.g., 10 mg).
Medchemexpress LLC Lauroyl coenzyme A (lithium) | 190063-12-8 | 99% | 1 MG
Lauroyl coenzyme A lithium salt is an intermediary in fatty acid synthesis or metabolism. It is formed by combining long-chain fatty acids (specifically lauric acid) with coenzyme A. This compound plays a role in lipid biosynthesis and fatty acid transport, where coenzyme A acts as a transport molecule to facilitate the movement and targeting of specific compounds.
- Intermediary in fatty acid synthesis or metabolism.
- Formed by combining long-chain fatty acids (lauric acid) with coenzyme A.
- Involved in lipid biosynthesis and fatty acid transport.
- Coenzyme A acts as a transport molecule to help move and target specific compounds.
- Purity: 99%.
- Appearance: White to off-white solid.
Medchemexpress LLC GlyH-101 | 328541-79-3 | 99.7% | 493.15 | 5 MG
GlyH-101 is a potent inhibitor of CFTR (Cystic Fibrosis Transmembrane conductance Regulator) and VSORC (Volume-Sensitive Outwardly Rectifying Chloride) conductance. It exhibits antiproliferative activity by inhibiting CFTR-like and VSORC currents and is intended for research use only.
- Potent CFTR inhibitor
- Potent and reversible VSORC inhibitor
- Exhibits antiproliferative activity in PCT and PS120 cells
- Inhibits CFTR-like current in PCT cells
- Inhibits VSORC current in PS120 and PCT cells
- Reduces cholera toxin-induced intestinal fluid secretion in mice
- Available as a solid, light yellow to yellow
- Soluble in DMSO
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.8% | 500 MG
Sodium lauroyl glutamate is an anionic amino acid surfactant primarily used in cleaning products. While it has the potential for irritant contact dermatitis, it also exhibits possible anti-irritating properties in surfactant mixtures on human skin. A 1% w/w solution demonstrates low irritation and has a pH value of 5.41.
- Anionic amino acid surfactant
- Mild surfactant
- Used mainly in cleaning products
- Exhibits possible anti-irritating potential in surfactant mixtures
- Low irritation to nude mouse skin at 1% w/w solution
- 1% w/w solution has a pH value of 5.41
- Appears as a white to off-white solid
Medchemexpress LLC PKUMDL-LC-101-D04 50mg | 2143896-83-5 | 378.94 g·mol⁻¹ | C14H23ClN4O2S2 | 50 MG
Small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used as a research tool to study ferroptosis and inflammation. Reported activity includes an approximate pEC50 of 4.7 and an ability to increase GPX4 activity in biochemical assays. Supplied as a solid with good solubility in DMSO for assay preparation.
- Allosteric activation of glutathione peroxidase 4 with reported pEC50 ≈ 4.7.
- Shown to increase GPX4 activity to about 150% in biochemical assays.
- Useful for probing ferroptosis and inflammation pathways in preclinical research.
- Supplied as a solid with high DMSO solubility for convenient dilution and assay use.
- Vendor-reported molecular formula and molecular weight provided for analytical reference.
Apexbio Technology LLC PKUMDL-LC-101-D04 2143896-83-5 10mg
PKUMDL-LC-101-D04 (CAS 2143896-83-5) is a small molecule allosteric activator of glutathione peroxidase 4 (GPX4) a key enzyme regulating ferroptosis In biochemical and cell extract assays PKUMDL-LC-101-D04 enhances GPX4 activity to 150% of baseline at concentrations of 20 M and 61 M respectively This compound serves as a valuable tool for investigating the modulation of ferroptosis through GPX4 activation and supports research into oxidative stress and cell death mechanisms
Medchemexpress LLC Rhodamine 101 chloride | 64339-18-0 | 527.05 g/mol | C32H31ClN2O3 | 10 MG
Rhodamine 101 chloride is a bright xanthene-class fluorescent dye with excitation and emission maxima at 565 nm and 595 nm, respectively. It is used for fluorescence microscopy, cellular staining, and as a red-spectrum reference standard. The solid is supplied in small laboratory pack sizes and should be stored protected from light and moisture; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Excitation 565 nm and emission 595 nm.
- Suitable for fluorescence microscopy and cellular staining.
- Useful as a reference standard in red-spectrum labeling.
- Available in small lab pack sizes, including 10 mg.
- Store sealed, protected from moisture and light.
Medchemexpress LLC UCPH-101 | 1118460-77-7 | 98.6% | 422.48 | 50 MG
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. It demonstrates cellular effects on HEK293 cells by inhibiting human EAAT1. This product is for research use only.
- Acts as an EAAT1 inhibitor
- Demonstrates cellular effects on HEK293 cells
- Inhibits human EAAT1 anion currents
Medchemexpress LLC RG-101 sodium | 00-00-0 | 95.4% | 8537.6 (free acid) | C295H410N78Na19O146P19S17 | 5 MG
RG-101 sodium is a hepatocyte-targeted N-acetylgalactosamine (GalNAc)-conjugated antisense oligonucleotide that antagonizes microRNA-122 (miR-122), a host factor important for hepatitis C virus replication. Supplied as a sodium salt, it is used in research to study miR-122 biology and antiviral mechanisms.
- Hepatocyte-targeted GalNAc conjugate for liver delivery.
- Antagonizes miR-122 to modulate hepatitis C virus-related pathways.
- High molecular weight oligonucleotide for sequence-specific activity.
- High purity (95.4%) suitable for research applications.
- Soluble in water; sonication may be required for dissolution.
- Recommended storage at -20°C; in solution store at -80°C for long-term.
Medchemexpress LLC Lei-101 hydrochloride | 2250025-91-1 | 99.4% | 508.99 | C23H26ClFN4O4S | 100MG
LEI-101 is a potent, selective cannabinoid CB2 receptor agonist used for biochemical and pharmacological research. It shows high selectivity for CB2 over CB1, is orally bioavailable, and is supplied as a solid for laboratory studies. Intended for research use only (not for human use).
- Selective CB2 receptor agonist with approximately 100-fold selectivity over CB1.
- Orally bioavailable, suitable for in vivo pharmacology studies.
- High purity (99.35%).
- Molecular weight 508.99 and formula C23H26ClFN4O4S.
- Soluble in DMSO (approx. 116.7 mg/mL).
- Intended for laboratory research use only, not for human consumption.
TARGETMOL CHEMICALS INC AV-101 5MG
Also available in 1mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. AV-101 (4-Cl-KYN) a prodrug antagonist at the glycine site of the NMDA receptor has antidepressant activity and reduces levodopa-induced dyskinesia in MPTP monkeys. purity: 98%