Dicarboxylic acids and derivatives
TARGETMOL CHEMICALS INC KHS 101 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation. Purity 98%
eMolecules Diethyl 2,2-thiodiacetate | 925-47-3 | MFCD00087932 | 5g
Ambeed | Diethyl 2,2-thiodiacetate | 5g | 600849984 | A926756 | | 925-47-3 | MFCD00087932 | 206.260 | C8H14O4S
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Selleck Chemical LLC Sulforhodamine 101-E0366-5MG
Sulforhodamine 101 (SR101) is a fluorescent dye and is widely used for astrocyte identification
LOXO-101 1223405-08-0 25mg
LOXO-101 (CAS 1223405-08-0) is a potent and selective inhibitor of the tropomyosin receptor kinase (TRK) family demonstrating low nanomolar inhibitory activity across all TRK isoforms LOXO-101 disrupts signaling mediated by neurotrophin receptors which are critical for neuronal development and survival In kinase profiling LOXO-101 exhibited minimal off-target activity with significant inhibition observed only for TNK2 (IC50 576 nM) and did not display hERG inhibition or QT prolongation effects In vivo studies revealed dose-dependent tumor growth suppression in xenograft models Clinically LOXO-101 has been evaluated for safety and pharmacokinetics and induced rapid tumor regression in a TRK fusion-positive patient highlighting its utility in studying TRK-driven malignancies
CUDC-101 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CUDC-101 is a potent inhibitor of HDAC EGFR and HER2 with IC50s of 4.4 2.4 and 15.7 nM respectively. purity: 99%
Selleck Chemical LLC CUDC-101 S1194-10mM/1mL
CUDC-101 is a potent multi-targeted inhibitor against HDAC EGFR and HER2 with IC50 of 4 4 nM 2 4 nM and 15 7 nM and inhibits class I/II HDACs but not class III Sir-type HDACs Phase 1
GlyH-101 328541-79-3 10mg
GlyH-101 (CAS 328541-79-3) is a cell-permeable glycinyl hydrazone derivative that acts as a selective inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel exhibiting a Ki of 1 4 M By blocking CFTR-mediated chloride transport GlyH-101 serves as a valuable tool for investigating CFTR function in epithelial physiology and pathophysiology as well as for studying mechanisms underlying cystic fibrosis and related disorders involving chloride ion dysregulation
Sigma Organic Chemistry Luperox(R) P, tert-Butyl peroxybenzoate | 5G | 614-45-9 | MFCD00008802
CAS #: 614-45-9
MDL #: MFCD00008802
Purity: >98 %
UNSPSC Code: 12352100
Molecular Weight: 194.23
GlyH-101 328541-79-3 10mM (in 1mL DMSO)
GlyH-101 (CAS 328541-79-3) is a cell-permeable glycinyl hydrazone derivative that acts as a selective inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel exhibiting a Ki of 1 4 M By blocking CFTR-mediated chloride transport GlyH-101 serves as a valuable tool for investigating CFTR function in epithelial physiology and pathophysiology as well as for studying mechanisms underlying cystic fibrosis and related disorders involving chloride ion dysregulation
Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101) 870281-82-6 50mg
CAL-101 (Idelalisib GS-1101 CAS 870281-82-6) is a selective inhibitor targeting the p110 isoform of phosphatidylinositol 3-kinase (PI3K) an enzyme involved in signaling pathways critical for proliferation and survival of malignant B cells By inhibiting PI3K p110 CAL-101 reduces PI3K-mediated phosphorylation of Akt and other downstream factors leading to enhanced PARP cleavage and caspase activation ultimately inducing apoptosis in malignant B cells CAL-101 has been demonstrated to counteract survival signals initiated by molecules such as CD40 ligand (CD40L) TNF- and fibronectin This agent is valuable in investigating B-cell malignancies
Sigma Organic Chemistry Luperox(R) LP, Lauroyl peroxide | 500G | 105-74-8 | MFCD00008964 | >=98%
Luperox(R) LP, Lauroyl peroxide, 500G
About This Item:
Storage: 2-8C
EINECS Number: 203-326-3
Sigma Organic Chemistry Luperox(R) LP, Lauroyl peroxide | 5G | 105-74-8 | MFCD00008964 | >=98%
Luperox(R) LP, Lauroyl peroxide, 5G
About This Item:
Storage: 2-8C
EINECS Number: 203-326-3
Sigma Organic Chemistry Luperox(R) 531M80, 1,1-Bis(tert-amylperoxy)cyclohexane solution | 500ML | 15667-10-4 | MFCD01863712
Luperox(R) 531M80, 1,1-Bis(tert-amylperoxy)cyclohexane solution, 500ML
About This Item:
Density: 0.898 g/mL at 25 C
Refractive Index: n20/D 1.442
Storage: 2-8C
Sigma Organic Chemistry Luperox(R) A75, Benzoyl peroxide | 100G | 94-36-0 | MFCD00003071 | 0.75
Luperox(R) A75, Benzoyl peroxide, 100G
About This Item:
Storage: 2-8C