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Dicarboxylic acids and derivatives

Organic compounds that contain two carboxyl groups; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from dicarboxylic acids.
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1

Apexbio Technology LLC Sulforhodamine 101 60311-02-6 25mg
SDP

Sulforhodamine 101 (60311-02-6) is a red-emitting fluorescent dye primarily utilized as a selective marker for astrocytes Sulforhodamine 101 selectively accumulates in astrocytes enabling differentiation from surrounding neuronal populations In neurobiological studies using live tissue imaging including acute brain slice preparations the dye facilitates visualization of astroglial cell morphology and cellular dynamics Based on these properties Sulforhodamine 101 holds research potential in the study of astrocyte-specific responses morphological characteristics and cell cell interactions within neuronal tissues

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2

Medchemexpress LLC 3-Pyridinecarboxamide, 1,2-dihydro-5-[4-[[(2S,6S)-6-(methoxymethyl)-6-methyl-1,4-dioxan-2-yl]methoxy]phenyl]-2-oxo-6-(trifluoromethyl)- | 2894060-67-2 | 99.5% | 456.41 | 25 MG
SDP

3-Pyridinecarboxamide, 1,2-dihydro-5-[4-[[(2S,6S)-6-(methoxymethyl)-6-methyl-1,4-dioxan-2-yl]methoxy]phenyl]-2-oxo-6-(trifluoromethyl)- | 2894060-67-2 | 99.5% | 456.41 | 25 MG

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3

Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101) 870281-82-6 100mg
SDP

CAL-101 (Idelalisib GS-1101 CAS 870281-82-6) is a selective inhibitor targeting the p110 isoform of phosphatidylinositol 3-kinase (PI3K) an enzyme involved in signaling pathways critical for proliferation and survival of malignant B cells By inhibiting PI3K p110 CAL-101 reduces PI3K-mediated phosphorylation of Akt and other downstream factors leading to enhanced PARP cleavage and caspase activation ultimately inducing apoptosis in malignant B cells CAL-101 has been demonstrated to counteract survival signals initiated by molecules such as CD40 ligand (CD40L) TNF- and fibronectin This agent is valuable in investigating B-cell malignancies

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4

Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101) 870281-82-6 50mg
SDP

CAL-101 (Idelalisib GS-1101 CAS 870281-82-6) is a selective inhibitor targeting the p110 isoform of phosphatidylinositol 3-kinase (PI3K) an enzyme involved in signaling pathways critical for proliferation and survival of malignant B cells By inhibiting PI3K p110 CAL-101 reduces PI3K-mediated phosphorylation of Akt and other downstream factors leading to enhanced PARP cleavage and caspase activation ultimately inducing apoptosis in malignant B cells CAL-101 has been demonstrated to counteract survival signals initiated by molecules such as CD40 ligand (CD40L) TNF- and fibronectin This agent is valuable in investigating B-cell malignancies

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5

Medchemexpress LLC Sulforhodamine 101 DHPE | 187099-99-6 | >95.0% | 1381.84 | C74H117N4O14PS2 | 1MG
SDP

Sulforhodamine 101 DHPE is a red fluorescent phospholipid probe created by conjugating dipalmitoyl phosphoethanolamine to sulforhodamine 101. It readily incorporates into lipid bilayers and is used for membrane imaging, monitoring probe colocalization in liposomes, and detecting protein-ligand interactions on supported bilayers. The dye exhibits excitation/emission peaks near 586/605 nm and is supplied as a powder with recommended cold storage.

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6

Medchemexpress LLC Tetradecanoic acid, 2,3-bis[(1-oxododecyl)oxy]propyl ester | 60175-30-6 | MFCD00063570 | 98.0% | 667.05 g/mol | C41H78O6 | 10 MG
SDP

1,2-Dilauroyl-3-myristoyl-rac-glycerol is a medium-chain triacylglycerol used as a research reagent and an intermediate for synthesizing functional edible oils and related lipid derivatives. It is typically supplied in small, research-scale quantities for laboratory studies.

  • Medium-chain triacylglycerol suitable for lipid synthesis and formulation.
  • High purity (98.0%) suitable for research applications.
  • Chemical formula C41H78O6; molecular weight 667.05 g/mol.
  • Appearance: white to off-white oil.
  • Provided in small research-scale quantities (e.g., 10 mg).

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7

Medchemexpress LLC 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | 99.1% | 434.49 g/mol | C24H26N4O4 | 1 ML
SDP

CUDC-101 is a small-molecule inhibitor that targets histone deacetylases (HDAC) and receptor tyrosine kinases EGFR and HER2. It is intended for research use in studies of signaling pathways, anti-proliferative activity, and preclinical cancer models. The compound is supplied as a high-purity reagent suitable for in vitro experiments.

  • Multi-target HDAC, EGFR, and HER2 inhibition
  • High purity suitable for research applications
  • Available as a ready-to-use 10 mM solution in DMSO (1 mL)
  • Confirmed molecular formula and molecular weight for analytical workflows
  • Intended for in vitro and preclinical research use

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8

Medchemexpress LLC 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 100 MG
SDP

CUDC-101 is a small-molecule research compound that concurrently inhibits histone deacetylases (HDACs) and receptor tyrosine kinases EGFR and HER2. It is used in preclinical cancer research to study combined epigenetic and kinase-targeted therapies.

  • Potent inhibition of HDAC, EGFR, and HER2 with IC50s of 4.4 nM, 2.4 nM, and 15.7 nM.
  • Contains a hydroxamic acid moiety associated with HDAC activity.
  • High purity (>98.0%) suitable for research applications.
  • Soluble in DMSO at 25 mg/mL (approximately 57.54 mM; may require ultrasonic agitation).
  • Molecular formula C24H26N4O4 and molecular weight 434.49 g/mol.

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9

Medchemexpress LLC 7-((4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 50 MG
SDP

CUDC-101 is a small-molecule research inhibitor of histone deacetylases (HDACs), epidermal growth factor receptor (EGFR), and HER2, used in preclinical cancer research to assess antiproliferative and target-specific effects.

  • Potent inhibitor of HDAC, EGFR, and HER2 with low-nanomolar activity.
  • Demonstrates broad antiproliferative effects across cancer cell lines.
  • Supplied as a light yellow to yellow powder for laboratory use.
  • High purity suitable for research applications (reported ≥98% by HPLC).
  • Available in small-mass packaging for research workflows.
  • Molecular weight 434.49 g/mol.

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10

Medchemexpress LLC Benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl] | 831217-40-4 | 98.2% | 931.12 g/mol | C54H66N4O10 | 1MG
SDP

MAL3-101 is a small-molecule allosteric inhibitor of heat shock protein 70 (HSP70) used in cellular and biochemical research. It inhibits HSP70 ATPase activity by blocking interaction with Hsp40 co-chaperones, perturbing protein folding and proteostasis pathways. The compound is supplied as a high-purity research reagent (CAS 831217-40-4) and is intended for in vitro and preclinical studies only.

  • Allosteric inhibitor of HSP70 ATPase activity.
  • Blocks Hsp40-Hsp70 interaction to disrupt protein folding.
  • Applicable to cellular models studying proteostasis and cancer biology.
  • High reported purity supports reproducible results.
  • Supplied in small quantities suitable for screening and pilot studies.
  • For research use only; not for human or veterinary use.

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11

Medchemexpress LLC N-(2-(1H-indol-3-yl)ethyl)-5-(5-fluoropyridin-3-yl)-3-methylpyrazolo[1,5-a]pyrimidin-7-amine | 2247950-73-6 | 98.0% | C22H19FN6 | 10MG
SDP

KYN-101 is a small-molecule, selective, orally active antagonist of the aryl hydrocarbon receptor (AHR) supplied for laboratory research. It reduces CYP1A1 mRNA expression and has demonstrated anti-cancer activity in preclinical studies, making it suitable for mechanistic studies of AHR signaling and oncology research.

  • Selective AHR inhibition with reported nanomolar potency.
  • Orally active in preclinical models.
  • Reduces CYP1A1 mRNA expression in cellular assays.
  • Useful for mechanistic studies of AHR signaling and cancer biology.
  • Available as solid and ready-to-use DMSO solutions for assay setup.
  • High purity suitable for research applications.

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12

Medchemexpress LLC N-(2-(1H-indol-3-yl)ethyl)-5-(5-fluoropyridin-3-yl)-3-methylpyrazolo[1,5-a]pyrimidin-7-amine | 2247950-73-6 | 98.0% | 386.42 g/mol | C22H19FN6 | 5 MG
SDP

KYN-101 is a potent, selective, orally active aryl hydrocarbon receptor (AHR) inhibitor used in research. It reduces CYP1A1 mRNA expression and has demonstrated anti-cancer activity in preclinical studies. Supplied as a small-quantity research compound with accompanying quality documentation.

  • Potent, selective aryl hydrocarbon receptor (AHR) inhibitor.
  • Orally active in preclinical models.
  • Decreases CYP1A1 mRNA expression in cellular assays.
  • Demonstrates anti-cancer activity in preclinical studies.
  • Supplied as a small research quantity (e.g., 5 mg) with COA and datasheet.
  • High purity (approximately 98.0%).
  • For research use only; not for human or clinical use.

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13

Medchemexpress LLC 3-cyclopropyl-1-[[4-[6-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-5-fluoropyridin-2-yl]phenyl]methyl]imi | 2250025-91-1 | Not found | 99.4% | 508.99 | C23H25FN4O4S·HCl | 25MG
SDP

LEI-101 hydrochloride is a potent, selective, orally bioavailable cannabinoid CB2 receptor agonist supplied for research use. It demonstrates strong functional activity at human CB2 receptors with substantially lower affinity for CB1 and minimal hERG binding, suitable for in vitro and in vivo pharmacology studies.

  • Purity 99.4%.
  • Reported activity pEC50 = 8 for human CB2.
  • Approximately 100-fold selectivity for CB2 over CB1.
  • Low hERG interaction (pKi < 4).
  • Soluble in DMSO; available as dry powder and 10 mM solution in DMSO.
  • Intended for research use only; not for human or clinical use.

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14

AdipoGen Sulforhodamine 101 acid Cl
SDP

Chemical. CAS 82354-19-6. Formula C31H29ClN2O6S2. MW 625.15. Synthetic. Sulforhodamine 101 sulfonyl chloride also called Texas Red sulfonyl chloride is a popular long wavelength amine-reactive rhodamine dye. Because the dye is quite unstable in water, reactions with amines in an aqueous solution must be carried out at low temperature over ice or at 4°C and usually at pH 8.5.

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15

AdipoGen Sulforhodamine 101 acid Cl
SDP

Chemical. CAS 82354-19-6. Formula C31H29ClN2O6S2. MW 625.15. Synthetic. Sulforhodamine 101 sulfonyl chloride also called Texas Red sulfonyl chloride is a popular long wavelength amine-reactive rhodamine dye. Because the dye is quite unstable in water, reactions with amines in an aqueous solution must be carried out at low temperature over ice or at 4°C and usually at pH 8.5.

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