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ICHORBIO LTD Cibisatamab Biosimilar - Research Grade
Bulk cibisatamab biosimilar. Available in 1mg, 5mg, 10mg, 20mg, 50mg and 100mg sizes. Low endotoxin, BSA and Azide Free. Research use only
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Medchemexpress LLC MedChemExpress Daraxonrasib, RAS (ON) Inhibitor, Orally Active, Non-Covalent
Daraxonrasib (RMC-6236) is an orally active, non-covalent RAS (ON) inhibitor. It disrupts the interaction of wild-type or mutant RAS proteins with the RAS binding domain of BRAF, inhibits pERK, and exhibits anti-tumor activity against KRAS mutant tumors.
- Orally active, non-covalent RAS (ON) inhibitor.
- Disrupts interaction of wild-type or mutant RAS proteins with BRAF’s RAS binding domain.
- Inhibits pERK.
- Has anti-tumor activity against KRAS mutant tumors.
- Potently inhibits the growth of KRAS mutant cancer cell lines HPAC and Capan-2.
- Shows dose-dependent antitumor activity in various human tumor xenograft models harboring prevalent KRAS mutations.
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