General Western Blot Reagents
Abcam C6 Ceramide, biologically active ceramide analog, 5MG
MW 397.6 Da, Purity >98%. Non-physiological and biologically active ceramide analog. Various pharmacological activities including activation of protein phosphatase 2A and MAPK, suppression of insulin-induced tyrosine phosphorylation and induction of cell cycle arrest at the G0/G1 transition. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Marimastat, Matri x metalloprotease (MMP) inhibitor, 10MG
MW 331.41 Da, Purity >98%. Potent matrix metalloproteinase inhibitor. Broad-spectrum inhibitor of all major MMPs. Prevents or reduces spread and growth of tumors.
The product is subject to the following: Abcam Restricted Use Statement
Abcam L-Mimosine, non-protein amino acid, 100MG
MW 198.18 g/mol, Purity >98%. Toxic non-protein amino acid originally isolated from Mimosa pudica. Arrests the cell cycle at the G1 phase in PC-3 cells and at the S phase in LNCaP cells, thus attenuating cell proliferation. Blocks cell cycle progression by chelating iron in asynchronous MDA-MB-453 human breast cancer cells. Arrests DNA synthesis by inhibiting deoxyribonucleotide metabolism. Prolyl hydroxylase (PHD) inhibitor stimulating VEGF production, and increasing proangiogenic capacity in dental pulp-derived cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam cis-Resveratrol, Antio x idant agent, 50MG
MW 228.24 Da, Purity >98%. Antioxidant agent. NADPH oxidase inhibitor. Blocks ROS production. Resveratrol (ab120726) isomer. Inhibits canonical and non-canonical inflammasomes in macrophages. Shows anti-inflammatory and antiproliferative effects. Orally bioavailable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ML-9, protein kinase inhibitor, 10MG
MW 361.3 Da, Purity >98%. Broad spectrum ATP-competitive protein kinase inhibitor (Ki values are 32, 4, and 54 μM for PKA, MLCK, and PKC respectively). Ca²+ channel blocker. Shows vasorelaxant effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam RGD (Arg-Gly-Asp), sequence involved in cell adhesion, 10MG
MW 346.34 Da, Purity >95%. RGD (Arg-Gly-Asp), sequence involved in cell adhesion. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-Methylumbelliferyl heptanoate, Fluorogenic lipase substrate, 500MG
MW 288.34 g/mol, Purity >95%. Fluorescent substrate for esterases and lipases. Also used to measure cell proliferation and viability.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sulforhodamine 101 acid chloride, amine-reactive rhodamine dye, 5MG
MW 625.2 Da, Purity >95%. Long wavelength red fluorescent amine-reactive rhodamine dye, also known as Texas Red. Useful for histological staining as well as in cell sorting experiments with fluorescent-activated cell sorting machines (FACS).
The product is subject to the following: Abcam Restricted Use Statement
Abcam alpha-Calcitonin Gene Related Peptide (human), CGRP agonist, 1MG
MW 3789.3 Da, Purity >95%. alpha-Calcitonin Gene Related Peptide (human), CGRP agonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Bufalin, Na+/K+-ATPase inhibitor, 10MG
MW 386.5 Da, Purity >98%. Na+/K+-ATPase inhibitor. Potent steroid receptor coactivators SRC-3 and SRC-1 inhibitor. Induces cell differentiation and apoptosis. Activates AP-1 via JNK. Shows antitumor effects *in vivo.*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-Methylumbelliferyl oleate, Fluorogenic substrate for lipases, 250MG
MW 440.61 g/mol, Purity >95%. Fluorogenic substrate for lipases, which can be used in aqueous solutions as well as several organic solvents.
The product is subject to the following: Abcam Restricted Use Statement
Abcam BTBCT, Europium beta-diketone chelate, 50MG
MW 604.9 Da, Purity >95%. Europium β-diketone chelate. Provides 8 times improved detection sensitivity compared to BHHCT-(Asc5314
The product is subject to the following: Abcam Restricted Use Statement
Abcam Phortress, Antitumor agent, 50MG
MW 459.4 Da, Purity >98%. Potent antitumor agent (IC₅₀ values for MCF-7 and MDA468 cells are 40 nM and 158 nM, respectively). Active against breast, ovarian and renal carcinomas. Taken up into sensitive cells followed by aryl hydrocarbon receptor binding and translocation into the nucleus. Requires metabolic activation by cytochrome P450 to generate cytotoxic species. Active in vitro and in vivo. Water soluble.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SBD-F (7-Fluorobenzofurazan-4-sulfonic acid ammonium salt), Fluorescent thiol indicator, 5MG
MW 235.2 Da, Purity >98%. Fluorescent thiol indicator. Reacts with sulfhydryl groups to produce highly fluorescent compounds. Attains low detection limits.
The product is subject to the following: Abcam Restricted Use Statement
Abcam NBD-Cl, Amine-reactive fluorogenic dye, 10G
MW 199.55 Da, Purity >98%. Amine-reactive, fluorogenic dye. Forms green fluorescent adducts with aliphatic amines and thiols. Labels proteins, peptides, amino acids and other biomolecules.
The product is subject to the following: Abcam Restricted Use Statement