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Filtered Search Results
Accela Chembio Inc 2-bromo-5-methylbenzoic Acid | 25g | 6967-82-4 | MFCD00079722 | 98% | Shelf Life: 1260 Days | Light Sensitive
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2-bromo-5-methylbenzoic Acid | 25g | 6967-82-4 | MFCD00079722 | 98% | Shelf Life: 1260 Days | Light Sensitive
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Medchemexpress LLC N-Acetylmuramic acid | 10597-89-4 | 99.9% | 293.27 | 5 MG
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N-Acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, crucial for maintaining cell shape and integrity. It inhibits spore germination by targeting a coat-associated hexosaminidase and a core enzyme. This compound is required for the proliferation and maintenance of cell shape in *Bacteroides forsythus*. Additionally, N-Acetylmuramic acid has demonstrated anti-inflammatory activity by inhibiting the p38 MAPK/NF-κB signaling pathway and is orally active.
- Destroys cell wall, enabling normal growth and typical filamentous morphology in *B. forsythus*.
- Reduces the expression of iNOS and COX-2, and inhibits the secretion of TNF-α and IL-1β in LPS-stimulated RAW264.7 cells.
- Inhibits *E. coli*-induced intestinal villus edema and thickening in mice, exhibiting anti-inflammatory activity.
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Medchemexpress LLC Isovaleric acid | 503-74-2 | 97.0% | 102.13 | 5 G
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Isovaleric acid is an orally active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. It can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders.
- Inhibits osteoclast differentiation by stimulating AMPK phosphorylation.
- Promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway.
- Reduces Na+, K+-ATPase activity in synaptic membranes.
- Has an inhibitory effect on the expression of osteoclast-related genes.
- Alleviates acetylcholine-induced colonic smooth muscle contraction.
- Ameliorates ovariectomy-induced osteoporosis in an ovariectomized mouse model.
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Medchemexpress LLC Simvastatin acid | 121009-77-6 | 95.5% | 50 MG
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Simvastatin acid is the hydrolyzed acid form of simvastatin that acts as an HMG-CoA reductase inhibitor and is supplied for biochemical and cell-based research applications; not for human use.
- Hydrolyzed active acid form of simvastatin.
- Inhibits HMG-CoA reductase activity in biochemical assays.
- Reduces indoxyl sulfate-mediated reactive oxygen species in cardiomyocytes.
- Molecular formula C25H40O6, molecular weight 436.58 g/mol.
- Available in milligram quantities (1 mg-100 mg) for research applications.
- Typical purity around 95.5% (supplier listed).
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Medchemexpress LLC Glycohyocholic acid | 32747-08-3 | >98.0% | 50 MG
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Analytical reference standard of glycohyocholic acid, a glycine-conjugated bile acid intended for research and analytical applications. Typical pack size is 50 MG; chemical formula C26H43NO6 and molecular weight ~465.6 g/mol. Purity is reported as ≥98% by some suppliers; verify the certificate of analysis.
- Analytical reference standard for use in research and analytical assays.
- Glycine-conjugated bile acid structure, useful as a metabolite standard.
- Chemical formula: C26H43NO6.
- Molecular weight: ~465.6 g/mol.
- Supplied as a 50 MG solid suitable for analytical preparation.
- Purity reported as ≥98% by some suppliers; check the certificate of analysis.
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Cayman Chemical Suberohydroxamic acid
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A competitive HDAC inhibitor that inhibits HDAC1 (IC50 = 0.25 μM) and HDAC3 (IC50 = 0.30 μM); causes cell differentiation, cell cycle arrest, or apoptosis
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Medchemexpress LLC Thyropropic acid 1mg | 1MG
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Thyropropic acid 1mg | 1MG
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Sigma Aldrich Fine Chemicals Biosciences Phosphatase substrate 100
REAGENT Phosphatase substrate 100
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Sigma Aldrich Fine Chemicals Biosciences L Carnosine 99 crystallin25G
L Carnosine ~99 crystallin25G
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Medchemexpress LLC TA 0910 acid-type 5mg | 103300-77-2 | 406.39 g·mol⁻¹ | C17H22N6O6 | 5 MG
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TA 0910 acid-type is a metabolite of TA-0910, a metabolically stable analogue of thyrotropin releasing hormone (TRH). It is supplied as a research reagent for in vitro studies and is available as solid powder and as DMSO solutions. Molecular formula C17H22N6O6; molecular weight 406.39 g·mol⁻¹. Not for human or veterinary use.
- Metabolite of a TRH analogue suitable for biochemical assays.
- Available as solid powder and 10 mM solutions in DMSO.
- Supplied in small research quantities (for example, 5 mg solid).
- Molecular formula C17H22N6O6 and molecular weight 406.39 g·mol⁻¹.
- Intended for research use only; not for human or veterinary use.
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Medchemexpress LLC 4-Fluoro-2,1,3-benzoxadiazole | 29270-55-1 | 98.8% | 10 G
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4-Fluoro-2,1,3-benzoxadiazol (4-Fluorobenzofurazan) is a fluorescent benzofurazan derivative.
- Fluorescent benzofurazan derivative.
- Target: Fluorescent Dye.
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AdipoGen NAI-97 Planosporicin
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Chemical. CAS 802917-82-4. Formula C90H125N27O28S5. MW 2193.5. Isolated from Planomonospora sp. Antibacterial class I lantibiotic. Inhibits cell wall synthesis and consequently bacterial growth by forming a complex with lipid intermediate II Lipid II, a key intermediate in peptidoglycan biosynthesis. Interfers with late stages of cell wall biosynthesis leading to accumulation of the soluble peptidoglycan precursor UDP-N-acetylmuramic acid-pentapeptide UDP-MurNAc-pentapeptide in the cytoplasm less efficient than NAI-107. Active against aerobic and anaerobic Gram-positive pathogens, including all antibiotic-resistant strains e.g. MRSA and VRE in whole cell and in vitro assays as well as in vivo.
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Sigma Aldrich Fine Chemicals Biosciences HiPrepTM 26 0 Desalting C
HiPrep(TM) 26/10 Desalting is a convenient easy-to-use column prepacked 53 mL column with Sephadex(R) G-25 Fine for desalting and buffer exchange.
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AdipoGen Chetomin
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Chemical. CAS 1403-36-7. Formula C31H30N6O6S4. MW 710.9. Isolated from Chaetomium sp. Antibiotic. Inhibitor of HIF-1 formation by disrupting the binding of p300 to both HIF-1alpha and HIF-2alpha. Histone H3K9 methyltransferases G9a and Suv39h inhibitor. Tumor growth inhibitor. Angiogenesis inhibitor. Potent immunosuppressor. Antibacterial and antifungal. Strong inducer of retinal pigment epithelium RPE.
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Cayman Chemical 20carboxy Arachidonic Acid
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures; ω-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing recombinant human CYP4F3B; 20-carboxy arachidonic acid inhibits ion transport in the kidneys; produces vasorelaxation of porcine coronary microvessels constricted with endothelin; binds to isolated ligand binding domains of peroxisome proliferator-activated receptor α (PPARα) (Kd = 0.87 ± 0.12 µM) and PPARγ (Kd = 1.7 ± 0.5 µM); a dual activator of PPARα and PPARγ in a transiently transfected COS-7 cell reporter system
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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