Hydroxybenzoic Acid Derivatives
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Filtered Search Results
AdipoGen Euphol
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Chemical. CAS 514-47-6. Formula C30H50O. MW 426.7. Euphol is a euphane-type triterpene alcohol that is structurally similar to cholesterol and has a wide range of pharmacological properties, including anticancer, anti-inflammatory, analgesic, antiviral and immunomodulatory effects. Euphol produces anti-inflammatory effects by mediating NF-kappaB, down-regulation of tumor necrosis factor-alpha and cyclooxygenase-2 and reduced activation of protein kinase C. Euphol inhibits the monoacylglycerol lipase MAGL activity via a reversible mechanism IC50=315nM. MAGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain. Euphol exerted in vitro and in vivo cytotoxicity against several cancer cell lines and glioma cells, through several cancer pathways.
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Medchemexpress LLC NRG1-beta 2 Human 100ug
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HRG1- 1 belongs to a family of structurally-related polypeptide growth factors derived from alternatively spliced genes induces Fn14 expression in MCF7 cells NRG1-beta 2 Protein Human is the recombinant human-derived NRG1-beta 2 protein expressed by E coli with tag free
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Selleck Chemical LLC JR-AB2-011-E1151-10MM/1ML
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JR-AB2-011 is a potent inhibitor of mTOR-mLST8-mSIN1-Rictor complex (mTORC2) which can block mTORC2 signaling and Rictor association with mTOR at lower effective concentrations
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Medchemexpress LLC Guluronic acid sodium | 32510-76-2 | 5 MG
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Guluronic acid sodium is an orally active oxidative stress modulator and anti-inflammatory agent. It down-regulates pro-inflammatory and oxidative stress-related genes while inhibiting enzymes like COX-2 and MMPs. Also up-regulating immunoregulatory genes, it suppresses cancer-related inflammation, tumor angiogenesis, cell adhesion, and metastasis. This compound is researched for multiple sclerosis, ankylosing spondylitis, breast cancer, and other inflammatory diseases.
- Acts as an oxidative stress modulator and anti-inflammatory agent.
- Down-regulates pro-inflammatory and oxidative stress-related genes.
- Inhibits COX-2, MMPs, and VEGF activities.
- Suppresses cancer-related inflammation, angiogenesis, and metastasis.
- Reduces immunosuppressive cell accumulation.
- Orally active.
- For research use only.
- Appearance: solid, white to light yellow.
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Selleck Chemical LLC Pachymic acid-E0214-5MG
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Pachymic acid(3-O-Acetyltumulosic acid) inhibits the activity of CYP2C9 with the IC50 of 21 25 M
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AdipoGen Nimbolide
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Chemical. CAS 25990-37-8. Formula C27H30O7. MW 466.52. Nimbolide is a limonoid tetranortriterpenoid shown to exhibit anti-malarial, anti-bacterial, anti-inflammatory, anti-obesity and anti-cancer activities. Nimbolide induces cell cycle arrest, DNA damage and apoptosis, and modulates autophagy in cancer cell lines. It inhibits pancreatic cancer cell growth and metastasis by inducing the excessive generation of ROS, reducing PI3K/Akt/mTOR and ERK signaling, and upregulating the pro-apoptotic proteins Bax, caspase-3 and PARP. Nimbolide inhibits auto-ubiquitination of the E3 ligase RNF114 and p21 ubiquitination in vitro. This compound impairs proliferation of triple-negative breast cancer cell lines. Nimbolide also induces apoptotic cell death in a Waldenstroms macroglobulinemia cell line BCWM1 and inhibits tumor growth in a xenograft model of Waldenstroms macroglobulinemia.
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eMolecules 1788873-66-4 | [trans-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methanol | Synthonix159.204 | C8H14FNO | 97.000 | OC[C@@]12CCCN1C[C@H](F)C2 | 500mg | 808556683
[trans-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methanol | Synthonix | 1788873-66-4159.204 | C8H14FNO | 97.000 | OC[C@@]12CCCN1C[C@H](F)C2 | 500mg | 808556683
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Cambridge Isotope Laboratories 3 6-Dichlorosalicylic acid (DCSA) (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
3 6-Dichlorosalicylic acid (DCSA) (unlabeled) 100 ug/mL in acetonitrile 1 2 mL
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Cambridge Isotope Laboratories Aminomethylphosphonic acid (unlabeled) 100 ug/mL in water 1 2 mL
Aminomethylphosphonic acid (unlabeled) 100 ug/mL in water 1 2 mL
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Medchemexpress LLC Nonadecanoic acid | 646-30-0 | MFCD00002754 | 298.50 | 1 ML
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Nonadecanoic acid is a saturated fatty acid provided as a 10 mM solution in 1 mL of DMSO.
- Saturated fatty acid
- 10 mM concentration
- 1 mL volume
- Supplied in DMSO solvent
- Purity of 98.0%
- Molecular weight of 298.50
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Sigma Aldrich Fine Chemicals Biosciences 19 Norethindrone 98 powder5G
19 Norethindrone 98 powder5G
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Medchemexpress LLC Linolelaidic acid | 506-21-8 | MFCD00004435 | 280.45 g/mol | C18H32O2 | 100 MG
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Linolelaidic acid is an omega-6 trans fatty acid used as a research reagent and analytical standard. It has been studied for nutritional applications, inflammatory and anti-parasitic activities, and cellular effects such as apoptosis and cell-cycle modulation.
- Omega-6 trans fatty acid used for research and analytical applications.
- Reported oral activity and relevance to enteral and parenteral nutrition studies.
- Demonstrates anti-inflammatory and anti-parasitic activity in vitro and in vivo models.
- Useful for studies of apoptosis, cell cycle, and endothelial cell responses.
- Available in multiple pack sizes and in solution formats for analytical use.
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Sigma Aldrich Fine Chemicals Biosciences fB23 2 98 HPLC25MG
fB23 2 98 HPLC25MG
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Medchemexpress LLC 2-Hydrazinobenzothiazole | 615-21-4 | 99.95% | C7H7N3S | 25 G
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2-Hydrazinobenzothiazole is a potent IDO1 inhibitor with an IC50 of 8 μM. It interacts with the IDO1 haem through hydrazine and has potential for immune system related diseases research. It appears as a white to off-white solid.
- Potent IDO1 inhibitor with an IC50 of 8 μM
- Interacts with IDO1 haem through hydrazine
- Potential for immune system related diseases research
- Appearance: solid
- Color: white to off-white
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 102940-86-3 | 2-Chloro-3-fluorobenzoic acid | Combi-Blocks | MFCD00973903 | 174.560 | C7H4ClFO2 | 98.000 | OC(=O)c1cccc(F)c1Cl | 100g | 205388001
2-Chloro-3-fluorobenzoic acid | Combi-Blocks | 102940-86-3 | MFCD00973903 | 174.560 | C7H4ClFO2 | 98.000 | OC(=O)c1cccc(F)c1Cl | 100g | 205388001
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More