Hydroxybenzoic Acid Derivatives
4-(Trifluoromethyl)salicylic Acid 98.0+%, TCI America™
CAS: 328-90-5 Molecular Formula: C8H5F3O3 Molecular Weight (g/mol): 206.12 MDL Number: MFCD01529657 InChI Key: XMLFPUBZFSJWCN-UHFFFAOYSA-N Synonym: 2-Hydroxy-4-(trifluoromethyl)benzoic Acid PubChem CID: 164578 IUPAC Name: 2-hydroxy-4-(trifluoromethyl)benzoic acid SMILES: OC(=O)C1=CC=C(C=C1O)C(F)(F)F
4-Fluoro-3-formyl-benzoic acid, 97%, Thermo Scientific™
CAS: 845885-90-7 Molecular Formula: C8H5FO3 Molecular Weight (g/mol): 168.123 InChI Key: SKPWEADPCJMLID-UHFFFAOYSA-N Synonym: 4-fluoro-3-formyl-benzoic acid,3-formyl-4-fluorobenzoic acid,4-fluoro-3-formylbenzoicacid,ksc495c1b PubChem CID: 2794818 IUPAC Name: 4-fluoro-3-formylbenzoic acid SMILES: C1=CC(=C(C=C1C(=O)O)C=O)F
4-Bromo-2-chlorobenzoic Acid 98.0+%, TCI America™
CAS: 59748-90-2 Molecular Formula: C7H4BrClO2 Molecular Weight (g/mol): 235.461 MDL Number: MFCD00040903 InChI Key: JAVZWSOFJKYSDY-UHFFFAOYSA-N Synonym: benzoic acid, 4-bromo-2-chloro,4-bromo-2-chlorobenzoicacid,2-chloro-4-bromobenzoic acid,4-bromo-2-chloro-benzoic acid,rarechem al bo 2371,attercop-chm at111793,zlchem 410,pubchem3586,acmc-1b03i,ksc274c2d PubChem CID: 108829 IUPAC Name: 4-bromo-2-chlorobenzoic acid SMILES: C1=CC(=C(C=C1Br)Cl)C(=O)O
Apexbio Technology LLC Taurolithocholic Acid MaxSpec Standard 516-90-5 100ug
Taurolithocholic Acid MaxSpec Standard (CAS 516-90-5) is a taurine-conjugated form of lithocholic acid classified as a secondary bile acid In cellular models taurolithocholic acid (TLCA) has been shown to elevate caspase-3 and caspase-7 activities in Hep3B cells expressing the sodium-taurocholate cotransporting polypeptide (NTCP) without affecting untransfected cells TLCA is also employed to induce cholestasis in ex vivo and in vivo liver models for the investigation of hepatobiliary function and toxicity Additionally its serum levels increase significantly following oral lipid tolerance tests in humans The MaxSpec Standard is quality-controlled for mass spectrometry-based quantitative assays
Medchemexpress LLC Taurolithocholic acid | 516-90-5 | 99.7% | 483.70 | 1 ML
Taurolithocholic acid | 516-90-5 | 99.7% | 483.70 | 1 ML
Medchemexpress LLC Taurolithocholic acid | 516-90-5 | 99.7% | 483.70 | 10 MG
Taurolithocholic acid is an orally active bile acid and antiviral agent. It functions by upregulating FADS2 through the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibiting SFTSV-induced ferroptosis, viral replication, and viral entry of HBV/HDV. It also reduces the release of IL-1β, lipid ROS, and LDH. This compound serves as an experimental model for hepatocellular cholestasis and offers protection against lethal SFTSV infection in mice, making it suitable for related research.
- Orally active bile acid and antiviral agent
- Upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis
- Inhibits SFTSV-induced ferroptosis, viral replication, and viral entry of HBV/HDV
- Reduces the release of IL-1β, lipid ROS, and LDH
- Experimental model compound for hepatocellular cholestasis
- Protects mice from lethal SFTSV infection
Medchemexpress LLC Taurolithocholic acid | 516-90-5 | 98.3% | 483.70 | 100 UG
Taurolithocholic acid | 516-90-5 | 98.3% | 483.70 | 100 UG
Medchemexpress LLC Taurolithocholic acid | 516-90-5 | 99.7% | 483.70 g·mol^-1 | C26H45NO5S | 5 MG
Taurolithocholic acid is a taurine-conjugated bile acid used as a research reagent. It functions as a calcium channel agonist and modulates cell viability, S phase entry, and DNA synthesis in RMCCA-1 cells, with reported effects on EGFR and ERK signaling. Batch-specific documentation is provided for analytical verification.
Apexbio Technology LLC 4-Methylumbelliferone (4-MU) 90-33-5 10mM (in 1mL DMSO)
4-Methylumbelliferone (4-MU) is a small-molecule inhibitor of hyaluronic acid (HA) synthesis commonly employed in biomedical research Excessive HA production often resulting from the activation of HA synthase 2 (HAS2) correlates with increased cell migration invasion and metastatic behavior in various tumor cell types Mechanistically 4-MU suppresses HA biosynthesis primarily through activation of neutral sphingomyelinase 2 (NSMase2) elevating intracellular ceramide levels Elevated ceramide subsequently stimulates the activity of protein phosphatase PP2A leading to reduced phosphorylation of Akt decreased HAS2 activity and inhibition of HA generation Additionally ceramide elevation induced by 4-MU promotes activation of p53 and caspase-3 signaling pathways alongside downregulation of SIRT1 collectively contributing to reduced tumor cell viability migration and metastasis in vitro Clinical studies investigating the therapeutic potential of 4-MU are ongoing
Medchemexpress LLC 4-Trifluoromethylsalicylic acid | 328-90-5 | MFCD01529657 | 99.9% | 206.12 | C8H5F3O3 | 1 ML
4-Trifluoromethylsalicylic acid (desacetyl triflusal) is an active metabolite of triflusal that functions as a platelet aggregation inhibitor. The compound is supplied as a research-grade analytical standard in solid form and as a ready-to-use solution for biochemical assays.
- High purity (99.93%) suitable for analytical applications.
- Molecular formula C8H5F3O3 and molecular weight 206.12.
- Supplied as solid and as a 10 mM solution in DMSO for convenience.
- Suitable as a reference standard for assay development and platelet function studies.
- Registered under CAS 328-90-5 for unambiguous identification.
Medchemexpress LLC 4-Acetylphenylboronic acid | 149104-90-5 | HY-32933 | 99.96% | 163.97 | 10 G
4-Acetylphenylboronic acid is a potent inhibitor of carbonic anhydrases II (CA II), with IC50s of 246 μM and 281.40 μM for bovine CA II (bCA II) and human CA II (hCA II). It can be obtained via mechanochemistry and solvent evaporation and exhibits a loss of the carbonyl group at 500-550 K. In vitro, 4-Acetylphenylboronic acid (30 μM) shows 18.1% inhibition of cells against the BJ Human fibroblast cell line, suggesting no cytotoxicity.
- Potent inhibitor of carbonic anhydrases II (CA II)
- Can be obtained via mechanochemistry and solvent evaporation
- No significant cytotoxicity against BJ Human fibroblast cell line at 30 μM
Medchemexpress LLC Penicillic acid | 90-65-3 | 99.8% | 170.16 | 5 MG
Penicillic acid | 90-65-3 | 99.8% | 170.16 | 5 MG
eMolecules 54337-90-5 | AstaTech | 34-DIHYDROXYBENZAMIDE | 0.25g | 268488976 | 36739 | 95 | MFCD00242737 | 153.137 | C7H7NO3
AstaTech | 34-DIHYDROXYBENZAMIDE | 0.25g | 268488976 | 36739 | 95.000 | 54337-90-5 | MFCD00242737 | 153.137 | C7H7NO3
Medchemexpress LLC DL-2-aminooctanoic acid | 644-90-6 | MFCD00008102 | 98.0% | 159.23 g/mol | C8H17NO2 | 5 G
2-Aminooctanoic acid (DL-α-aminocaprylic acid) is an alpha-amino fatty acid supplied as the racemic DL mixture. It is used as a synthetic building block and research reagent in peptide synthesis, organic synthesis, and biochemical studies where an aminated caprylic acid derivative is required.
- Racemic DL mixture for research applications.
- Purity 98.0%.
- Molecular formula C8H17NO2; molecular weight 159.23 g/mol.
- Powder form suitable for coupling and synthetic transformations.
- Available in multiple small pack sizes for lab use.
Medchemexpress LLC Benzene, 2,4-dimethoxy-1-methyl- | 38064-90-3 | MFCD00010749 | ≥97.0% | 152.19 g/mol | C9H12O2 | 5 G
2,4-Dimethoxytoluene is an aromatic biochemical reagent used in laboratory research for synthesis and analytical applications. It is typically a colorless to pale-yellow liquid supplied in small quantities for bench-scale work and is intended for research use only.
- Chemical name: Benzene, 2,4-dimethoxy-1-methyl-.
- CAS number: 38064-90-3.
- Molecular formula C9H12O2; molecular weight 152.19 g/mol.
- Purity ≥97.0% by assay.
- Available in small pack sizes such as 5 G for bench-scale use.
- Store at room temperature (solid); in solvent, refrigerate or freeze for long-term storage.