Oligonucleotides
Biotium CD43(SPN/839), CF740 conjugate, 0.1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low ab
Medchemexpress LLC sEH inhibitor-1 | 1208549-68-1 | 99.6% | 1 MG
sEH inhibitor-1 (compound TCPU) is a research-grade, orally active inhibitor of soluble epoxide hydrolase (sEH) supplied as a powder for biochemical and preclinical studies. It shows sub-nanomolar to low-nanomolar potency in enzymatic assays and is intended for in vitro and in vivo research.
- Potent sEH inhibition: human IC50 0.4 nM, murine IC50 5.3 nM.
- High purity, typically 99.6%.
- Molecular weight 371.35; formula C17H20F3N3O3.
- Stable as powder at -20°C for long-term storage.
- Suitable for in vitro enzymatic assays and in vivo preclinical studies.
Cayman Chemical Cre mRNACap-1m1 100ug
An mRNA for the expression of Cre; encapsulation in LNPs can be used for mRNA delivery and expression of Cre in vitro or in vivo
Cayman Chemical Cre mRNACap-1m1 1mg
An mRNA for the expression of Cre; encapsulation in LNPs can be used for mRNA delivery and expression of Cre in vitro or in vivo
Biotium SOX9 / SRY-box 9 (PCRP-SOX9-1E5), CF488A conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are n
Medchemexpress LLC sEH inhibitor-7 | 340221-20-7 | 99.5% | 247.33 | 25 MG
sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH). Soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation.
- Inhibitor of soluble epoxide hydrolase (sEH)
- IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH)
- Plays an important role in the metabolism of endogenous chemical mediators
- Involved in the regulation of blood pressure and inflammation
- Purity: 99.5%
- Appearance: solid
- Color: off-white to light yellow
- Molecular weight: 247.33
- CAS No.: 340221-20-7
- Solubility: 100 mg/mL in DMSO
Enzo Life Sciences ODN 2006 (TLRGRADE™) (synthetic) (100µg)
CpG oligodeoxynucleotide (Type B) with phosphorothioate backbone. Specific ligand for human and mouse TLR9 (Toll-like receptor 9). Formulation: Lyophilized. Sterile. Long Term Storage: +4°C.
Biotium EZH2 / KMT6(EZH2/2536), CF740 conjugate, 0.1mg/mL
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
ABclonal Technology EZH2/KMT6 Rabbit pAb
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
Biotium pS2(GE2), CF740 conjugate, 0.1mg/mL
This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an incr