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Filtered Search Results
Medchemexpress LLC Clarithromycin | 81103-11-9 | 747.95 | 1 ML
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Clarithromycin is an inhibitor and agonist with broad-spectrum antimicrobial activity. It inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with an IC50 (Ki) value of 56 (43) μM. Clarithromycin also significantly inhibits the hERG potassium current and affects autophagic flux by impairing the signaling pathway linking hERG1 and PI3K.
- Targets bacterial, cytochrome P450, and autophagy.
- Acts as an antibiotic.
- Relevant for research in infection and cancer.
- Inhibits CYP3A4-catalyzed triazolam alpha-hydroxylation.
- Significantly inhibits the hERG potassium current.
- Impairs autophagic flux by affecting the hERG1 and PI3K signaling pathway.
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Medchemexpress LLC Geldanamycin-FITC | 2969156-01-0 | 1034.18 | 1 MG
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Geldanamycin-FITC is a fluorescent probe derived from Geldanamycin. It is utilized in fluorescence polarization assays for HSP90 inhibitors and can also detect cell surface HSP90.
- Fluorescent probe
- Used in fluorescence polarization assays for HSP90 inhibitors
- Detects cell surface HSP90
- Excitation (Ex): 488 nm
- Emission (Em): 515 nm
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Apexbio Technology LLC Dacarbazine 4342-03-4 200mg
Dacarbazine (CAS 4342-03-4) is a triazene-based alkylating agent widely used in biomedical research and oncology Upon metabolic activation dacarbazine generates reactive methylating species that transfer methyl groups primarily to the O6 and N7 positions of guanine bases within DNA This alkylation promotes DNA strand cross-linking and mispairing ultimately inducing apoptosis in rapidly dividing cells Dacarbazine is commonly applied in studies modeling malignant melanoma Hodgkin lymphoma sarcoma and pancreatic islet cell carcinoma Its mechanism of DNA damage and cytotoxicity also informs research into chemoresistance and combination chemotherapy regimens
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eMolecules 848249-10-5 | Medchem Express | HS-243 | 5mg | 721310160 | HY-134911 | 324.34 | C17H16N4O3
Medchem Express | HS-243 | 5mg | 721310160 | HY-134911 | 848249-10-5 | 324.340 | C17H16N4O3
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Medchemexpress LLC HY-75054 50mg Medchemexpress, Abiraterone acetate CAS:154229-18-2 Purity:>98%
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Medchemexpress, HY-75054 50mg Abiraterone acetate CAS:154229-18-2 Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a prodrug form of Abiraterone (CB7598). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Tipiracil hydrochloride | 183204-72-0 | 99.9% | C9H12Cl2N4O2 | 5 MG
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Tipiracil hydrochloride is a thymidine phosphorylase inhibitor (TPI) primarily utilized in cancer research. It demonstrates antiangiogenic effects and effectively inhibits the proliferation of endothelial cells.
- Potent inhibitor of thymidine phosphorylase
- Used for cancer research
- Exhibits antiangiogenic effects
- Inhibits proliferation of endothelial cells
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![Medchemexpress LLC 5-chloro-N-[5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl]-2-hydroxybenzamide | 212135-62-1 | 96.0% | C22H15Cl3N2O2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261216.png-250.jpg)
Medchemexpress LLC 5-chloro-N-[5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl]-2-hydroxybenzamide | 212135-62-1 | 96.0% | C22H15Cl3N2O2 | 10MG
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ZT-1a is a small-molecule, non-ATP-competitive inhibitor of STE20/SPS1-related proline-alanine-rich kinase (SPAK/STK39). It has been reported to inhibit SPAK enzymatic activity with mid-micromolar IC50 values and is used as a biochemical probe to study SPAK-dependent regulation of ion transporters.
- Non-ATP-competitive inhibition of SPAK
- Reported IC50 values: 44.3 μM (0.01 mM ATP), 35.0 μM (0.1 mM ATP), 46.7 μM (1 mM ATP)
- Molecular formula: C22H15Cl3N2O2
- Molecular weight: 445.73 g·mol⁻¹
- Useful as a biochemical probe for studying SPAK-dependent signaling
- Available in small research quantities for in vitro studies
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Medchemexpress LLC HY-113409 1g Medchemexpress, 3-Hydroxyisovaleric acid CAS:625-08-1 Purity:98%
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Medchemexpress,HY-113409 1g 3-Hydroxyisovaleric acid CAS:625-08-1 Formula:C5H10O3 3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Neomycin sulfate United States Pharmacopeia (USP) Reference Standard | 1405-10-3 | 200MG
Neomycin sulfate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 908.88 | 1405-10-3 | 200MG
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![Medchemexpress LLC 1-cyano-3-(4-cyanophenyl)-2-[(2R)-3,3-dimethylbutan-2-yl]guanidine | 220641-11-2 | MFCD30747839 | 99.6% | 269.34 g/mol | C15H19N5 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000214212.png-250.jpg)
Medchemexpress LLC 1-cyano-3-(4-cyanophenyl)-2-[(2R)-3,3-dimethylbutan-2-yl]guanidine | 220641-11-2 | MFCD30747839 | 99.6% | 269.34 g/mol | C15H19N5 | 50 MG
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Naminidil is a cyanoguanidine small molecule that acts as an ATP-sensitive potassium (KATP) channel opener. It is provided as a research-grade reagent for in vitro and in vivo pharmacological studies of potassium channel function and cardiovascular mechanisms. The compound has molecular formula C15H19N5, molecular weight 269.34 g/mol, and reported CAS number 220641-11-2.
- Acts as an ATP-sensitive potassium (KATP) channel opener for functional studies.
- High purity (about 99.6%) suitable for research applications.
- Available in multiple pack sizes including 50 mg for flexible dosing.
- Characterized molecular properties (C15H19N5; MW 269.34 g/mol).
- Provided with analytical documentation such as COA and SDS for safety and quality assurance.
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Biotang Inc G418,; 1 gm
G418,; 1 gm.
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AdipoGen Nigericin . sodium salt,Chemical. CAS: 28643-80-3.
Nigericin . sodium salt, AdipoGen Life Sciences. Chemical. CAS: 28643-80-3. Formula: C40H67O11 . Na. MW: 724.0 . 23.0. Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H+, K+, Na+, Pb2+. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential of mitochondria. NLRP3/NALP3 activator. Signals through pannexin-1 to induce caspase-1 maturation and IL-1beta processing and release. Autophagy modulator
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Research Products International Corp Cefixime Trihydrate, 1 Gram
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In the life sciences, Cefixime Trihydrate is widely utilized to study bacterial susceptibility and resistance patterns. It helps researchers investigate the effectiveness of antibiotics against various bacterial strains, contributing to a deeper understanding of microbial biology and antibiotic development.
In pharmaceutical research, Cefixime Trihydrate serves as a reference standard for antibiotic formulation and efficacy testing. Researchers rely on it to develop new antibiotics, optimize existing ones, and combat emerging antibiotic-resistant bacteria.
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CPC Scientific H-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2 (trifluoroacetate salt) 1MG
Potent antagonist of PTH-related protein (1-34) in vitro and in vivo.ONE-LETTER SEQUENCE: LLHDKGKSIQDLRRRFFLHHLIAEIHTA-NH2MOLECULAR FORMULA: C153H247N49O37MOLECULAR WEIGHT:3364.95STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [115695-30-2], SYNONYMS: pTHrP (7-34) amide (human, mouse, rat), pTH-Related Protein (7-34) amide (human, mouse, rat)RESEARCH AREA: OsteoporosisREFERENCES: R.L. McKee et al., J. Bone and Mineral Res., 3, S73 (1988)
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Medchemexpress LLC BICYCLOMYCIN BENZOATE 10MG
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Medchemexpress,HY-101128 10mg Bicyclomycin benzoate FR2054 CAS:37134-40-0 Formula:C19H22N2O8 Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered
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