Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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1,981 – 1,995 of 7,080 results

1,981

Apexbio Technology LLC Thonzonium Bromide,50mg CAS# 553-08-2

Thonzonium Bromide is a surface active agent and an inhibitor of V-ATPase proton transport with EC50 value of 69 µM [1] [2].Vacuolar ATPases (V-ATPases) are proton pumps that maintain pH homeostasis. V-ATPases couple the energy of ATP hydrolysis to proton transport across intracellular membranes [2].Thonzonium Bromide is a surface active agent and an inhibitor of V-ATPase proton transport. In wild-type yeast cells, thonzonium bromide significantly decreased the cytosolic pH to 6.22. In vacuolar membrane vesicles, thonzonium bromide inhibited proton transport with EC50 value of 69 µM in a dose-dependent way. However, thonzonium bromide didn’t inhibit ATP hydrolysis, which suggested that thonzonium bromide uncoupled V-ATPase proton pumps. In wild-type yeast cells, thonzonium bromide (1 µM) didn’t inhibit cell growth. Other sizes are also available. Please inqury us for quote.

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1,982

eMolecules Medchem Express / 6-Aminochrysene / 25mg / 446259284 / HY-108315 / / 2642-98-0 / MFCD00003699 / 243.309 / C18H13N

Medchem Express / 6-Aminochrysene / 25mg / 446259284 / HY-108315 / / 2642-98-0 / MFCD00003699 / 243.309 / C18H13N

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1,983

Selleck Chemical LLC Isoxazole 9

Isoxazole 9 (Isx-9) is a synthetic promotor of adult neurogenesis by triggering neuronal differentiation of adult neural stem/precursor cells (NSPCs) Isoxazole 9 (Isx-9) activates multiple pathways including TGF- induced epithelial mesenchymal transition (EMT) signaling canonical and non-canonical Wnt signaling at different stages of cardiac differentiation

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1,984

Medchemexpress LLC Butyryltimolol | 106351-79-5 | MFCD32898870 | 98.0% | 386.51 g·mol⁻¹ | C17H30N4O4S | 50 MG

Butyryltimolol is a β-adrenergic blocker and a lipophilic ester prodrug of timolol that improves corneal penetration and is used in ocular delivery research. Reported properties include molecular formula C17H30N4O4S, molecular weight ≈386.51 g·mol⁻¹, and typical purity ~98.0%.

Improves corneal penetration of timolol.
Acts as a β-adrenergic blocker and prodrug of timolol.
Lipophilic ester structure enhances ocular delivery.
Supplied as a research-grade material with high reported purity.
Suitable for ocular pharmacology and formulation studies.

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1,985

Medchemexpress LLC HY-101490 5mg Medchemexpress, PDE1-IN-2 CAS:1904611-63-7 Purity:>98%

Medchemexpress, HY-101490 5mg PDE1-IN-2 CAS:1904611-63-7 PDE1-IN-2 is an inhibitor of PDE1 extracted from patent WO2016/55618 A1, example 31; has IC 50 values of 6, 140 and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,986

Medchemexpress LLC HY-10181 200mg Medchemexpress, Dasatinib CAS:302962-49-8 Purity:>98%

Medchemexpress, HY-10181 200mg Dasatinib CAS:302962-49-8 Dasatinib (BMS-354825) is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase inhibitor with IC50s of 0.6 nM, 0.8 nM, respectively. Dasatinib also inhibits Abl, Src, Fyn, c-Kit and c-KitD816V with IC50s of 2.8 nM, 79 nM and 37 nM, respectively. Dasatinib also induces apoptosis and autophagy. Dasatinib shows potently antitumor activity and has the potential for chronic myelogenous leukemia (CML) treatment[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,987

Medchemexpress LLC HY-10585 5g Medchemexpress, Valproic acid VPA;2-Propylpentanoic Acid CAS:99-66-1 Purity:98%

Medchemexpress,HY-10585 5g Valproic acid VPA;2-Propylpentanoic Acid CAS:99-66-1 Formula:C8H16O2 Valproic acid is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2; Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,988

Medchemexpress LLC Kasugamycin | 6980-18-3 | 99.8% | 1 G

Kasugamycin (Ksg) is an antibiotic that binds to both the 30S and 70S ribosome, but not isolated 50S subunits. It mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.

Binds to 30S and 70S ribosomes
Inhibits canonical translation initiation
Destabilizes tRNA binding
Purity of 99.82%
Suitable for research use

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1,989

Medchemexpress LLC HY-101784 100mg Medchemexpress, NE 52-QQ57 CAS:1401728-56-0 Purity:>98%

Medchemexpress, HY-101784 100mg NE 52-QQ57 CAS:1401728-56-0 NE 52-QQ57 is a selective, and orally available GPR4 antagonist with an IC 50 of 70 nM [1] . Anti-inflammatory activities [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,990

Medchemexpress LLC RTI-7470-44 | 825658-63-7 | 99.9% | C19H11ClF3N5OS | 10MG

RTI-7470-44 is a potent, selective, blood-brain barrier-penetrant antagonist of human trace amine-associated receptor 1 (hTAAR1) intended for preclinical research. It shows low-nanomolar potency and is used in electrophysiology and in vivo studies to probe dopaminergic neuron activity relevant to schizophrenia, substance addiction, and Parkinson's disease.

Potent, selective hTAAR1 antagonist.
Blood-brain barrier penetrant, enabling CNS studies.
Low-nanomolar potency against hTAAR1.
High purity suitable for biochemical and in vivo experiments.
Applicable to electrophysiology and behavioral models.

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1,991

Selleck Chemical LLC Rapamycin (Sirolimus) 100mg 53123-88-9 AY 22989NSC-2260804

Rapamycin (Sirolimus, AY 22989, NSC-2260804) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.

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1,992

Medchemexpress LLC HY-B0278 100mg Medchemexpress, Bacitracin (Zinc) CAS:1405-89-6 Purity:>98%

Medchemexpress, HY-B0278 100mg Bacitracin (Zinc) CAS:1405-89-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,993

Medchemexpress LLC HY-10452 100mg , MLN9708 Ixazomib citrate CAS:1239908-20-3 Purity:98%

Medchemexpress, HY-10452 100mg MLN9708 Ixazomib citrate CAS:1239908-20-3 Formula:C20H23BCl2N2O9 IC50: 3.4 nM (20S proteasome β5), 31 nM (20S proteasome β1), 3500 nM (20S proteasome β2) Purity:98% MLN9708 rapidly hydrolyzes to MLN2238, which is a selective, orally bioavailable, second-generation proteasome inhibitor, inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC 50 value of 3.4 nM ( K i of 0.93 nM), and also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites with IC 50 of 31 and 3500 nM, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,994

Apexbio Technology LLC Kif15-IN-1(Synonyms: Kif15 inhibitor 1, Kif15-IN1, Kif15 inhibitor I, KIF15-IN-1, Kif15 motor protein inhibitor), 2mg, CAS: 672926-32-8.

Kif15-IN-1 (CAS 672926-32-8) is a small molecule inhibitor targeting kinesin family member 15 (Kif15) also termed kinesin-12 or HKLP2 Kif15 is a kinesin-related motor protein expressed during mitosis crucially involved in the formation and stabilization of bipolar microtubule spindles acting redundantly with KIF11 (Eg5) Inhibition of Kif15 by Kif15-IN-1 results in suppression of tumor cell proliferation highlighting its utility in cell biology research focused on mitotic spindle mechanics and its potential in oncology as a candidate for antiproliferative strategies

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1,995

Medchemexpress LLC Biotin-PEG6-thalidomide | 2144775-48-2 | MFCD31561114 | 98.3% | C37H53N5O12S | 10MG

Biotin-PEG6-thalidomide is a biotinylated polyethylene glycol (PEG6)-linked thalidomide derivative used as a PROTAC linker and cereblon (CRBN) affinity probe for targeted protein degradation research. It provides a hydrophilic spacer and a biotin handle to facilitate synthesis, biochemical assays, and affinity-based capture of protein complexes. Supplied for research use only.

Provides a PEG6 spacer to increase solubility and flexibility
Contains a thalidomide-derived moiety for cereblon binding
Includes a biotin tag for affinity capture and pull-down assays
Suitable for PROTAC synthesis and CRBN-binding studies
Compatible with common organic solvents and assay conditions

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Antibiotics

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Apexbio Technology LLC Thonzonium Bromide,50mg CAS# 553-08-2 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC Isoxazole 9 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Butyryltimolol | 106351-79-5 | MFCD32898870 | 98.0% | 386.51 g·mol⁻¹ | C17H30N4O4S | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-101490 5mg Medchemexpress, PDE1-IN-2 CAS:1904611-63-7 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10181 200mg Medchemexpress, Dasatinib CAS:302962-49-8 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10585 5g Medchemexpress, Valproic acid VPA;2-Propylpentanoic Acid CAS:99-66-1 Purity:98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Kasugamycin | 6980-18-3 | 99.8% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-101784 100mg Medchemexpress, NE 52-QQ57 CAS:1401728-56-0 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC RTI-7470-44 | 825658-63-7 | 99.9% | C19H11ClF3N5OS | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC Rapamycin (Sirolimus) 100mg 53123-88-9 AY 22989NSC-2260804 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-B0278 100mg Medchemexpress, Bacitracin (Zinc) CAS:1405-89-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10452 100mg , MLN9708 Ixazomib citrate CAS:1239908-20-3 Purity:98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Kif15-IN-1(Synonyms: Kif15 inhibitor 1, Kif15-IN1, Kif15 inhibitor I, KIF15-IN-1, Kif15 motor protein inhibitor), 2mg, CAS: 672926-32-8. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Biotin-PEG6-thalidomide | 2144775-48-2 | MFCD31561114 | 98.3% | C37H53N5O12S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More