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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Nilutamide solid | 63612-50-0 | MFCD00864670 | 1G
Nilutamide solid | Mol Wt: 317.22 | 63612-50-0 | MFCD00864670 | 1G
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Cayman Chemical DIrIthromycIn 1g
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A macrolide antibiotic and prodrug of erythromycylamine that has outstanding activity against Campylobacter
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Sigma Aldrich Fine Chemicals Biosciences Chlortetracycline Selective Supplement suitable for microbiology | 57-62-5 | MFCD00864876 | 5VL
Chlortetracycline Selective Supplement suitable for microbiology | Mol Wt: 478.88 | 57-62-5 | MFCD00864876 | 5VL
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Medchemexpress LLC Geldanamycin-FITC | 2969156-01-0 | MFCD32068377 | 98.4% | C55H63N5O13S | 10MG
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Geldanamycin-FITC is a fluorescein (FITC)-labeled derivative of geldanamycin used as a fluorescent probe for HSP90. It is suitable for fluorescence polarization assays and for detection of cell-surface HSP90, with excitation/emission at 488/515 nm.
- Fluorescein (FITC)-labeled geldanamycin probe.
- Designed for fluorescence polarization assays.
- Detects cell-surface HSP90 (Ex/Em = 488/515 nm).
- High purity (~98.4%).
- Molecular formula C55H63N5O13S; molecular weight 1,034.18.
- Available in multiple small-molecule pack sizes.
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Medchemexpress LLC MRTX-EX185 (formic) | 2988148-70-3 | 97.2% | C34H35FN6O4 | 10MG
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MRTX-EX185 (formic) is a small-molecule inhibitor of KRAS with potent activity against the oncogenic G12D mutant (IC50 = 90 nM). It binds both GDP-loaded and GNP (GTP-mimetic) states of KRAS and is intended for biochemical, cellular, and tumor-model research. The compound is supplied as a purified solid (yellow to brown), with reported purity around 97.2%, molecular formula C34H35FN6O4, and molecular weight 610.68 g·mol⁻¹.
- Potent KRAS G12D inhibition (IC50 = 90 nM).
- Binds both GDP-loaded and GTP-mimetic states of KRAS.
- Applicable to in vitro and in vivo research studies.
- High reported purity, suitable for research use.
- Readily soluble in DMSO (125 mg/mL) for assay preparation.
- Stable as powder when stored at -20°C for long-term storage.
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Research Products International Corp Bafilomycin A1, 1 Milligram
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Bafilomycin A1 is a potent and selective inhibitor of the vacuolar-type H+-ATPase (V-ATPase), an enzyme responsible for maintaining acidic pH in cellular compartments such as lysosomes and endosomes.
In the life science field, Bafilomycin A1 is primarily used as a research tool to investigate the role of V-ATPase and lysosomal acidification in various cellular processes. By inhibiting V-ATPase, Bafilomycin A1 disrupts the acidification of cellular compartments, which in turn affects processes such as protein degradation, autophagy, endocytosis, and vesicular trafficking.
Bafilomycin A1 can be used to study autophagy, a cellular process involved in the degradation and recycling of cellular components. By inhibiting V-ATPase, Bafilomycin A1 blocks the final step of autophagy, preventing the fusion of autophagosomes with lysosomes and thereby inhibiting autophagic degradation.
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Research Products International Corp Amikacin, 1 Gram
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Amikacin is an aminoglycoside antibiotic. It is often utilized in microbiology and molecular biology laboratories and functions by inhibiting bacterial protein synthesis. Additionally, it binds to the 30S ribosomal subunit of bacteria, leading to the misreading of mRNA and ultimately preventing the synthesis of bacterial proteins. Due to its mechanism of action, amikacin is effective against a wide range of Gram-negative and some Gram-positive bacteria.
Commonly used as a selective agent in cell culture and molecular biology experiments. May be included in culture media to selectively grow cells that have been genetically modified to express resistance to this antibiotic. This is often achieved by introducing a plasmid or vector containing an amikacin resistance gene into the cells.
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Research Products International Corp Cefoperazone, Sodium Salt, 5 Grams
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Cefoperazone Sodium Salt is a third-generation cephalosporin antibiotic. Cefoperazone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This disruption interferes with the final stages of peptidoglycan synthesis in the bacterial cell wall, leading to structural instability and eventual cell lysis.
Cefoperazone is effective against a broad range of bacteria, both Gram-positive and Gram-negative. Cefoperazone Sodium Salt is often used as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Its inclusion allows for the specific growth of bacteria lacking resistance to cefoperazone.
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Medchemexpress LLC Lu AE98134 | 849000-18-6 | 98.1% | C21H23N5O3S | 10MG
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Lu AE98134 is a small-molecule activator and positive modulator of Nav1.1 voltage-gated sodium channels, used in research to probe sodium channel function and central nervous system disease models. It shows selectivity for Nav1.1 while also increasing Nav1.2 and Nav1.5 activity, and is supplied with analytical data supporting research use.
- Selective activator of Nav1.1 with activity at Nav1.2 and Nav1.5.
- High purity suitable for research (≈98.1%).
- High solubility in DMSO for in vitro preparation.
- Recommended storage conditions provided for powder and solutions.
- Available in small pack sizes for experimental use.
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Biotium DIA
DiA 4-(4-Dihexadecylaminostyryl)-N-methylpyridinium iodide) is a green fluorescent membrane dye which diffuses much faster than DiO in cell membranes. DiA and DiI have been used together for two color membrane staining. Properties: Red solid soluble in DMSO; Store at 4°C and protect from light, especially in solution; C46H79IN2; MW: 787; [114041-00-8]
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Medchemexpress LLC HY-B0510 500mg , Trimethoprim CAS:738-70-5 Purity:>98%
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HY-B0510 500mg Trimethoprim CAS: 738-70-5 Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Clindamycin hydrochloride lincosamide antibiotic | 21462-39-5 | MFCD07793327 | 100MG
Clindamycin hydrochloride lincosamide antibiotic | Mol Wt: 461.44 | 21462-39-5 | MFCD07793327 | 100MG
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Cell Signaling Technology Anisomycin 10 mg
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Anisomycin 10 mg ..
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Medchemexpress LLC Cdk9-in-13 (compound 38) | 2768712-71-4 | MFCD11162707 | 99.9% | C27H35N5O2 | 10MG
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CDK9-IN-13 is a research small-molecule inhibitor selective for cyclin-dependent kinase 9 (CDK9). Reported as compound 38, it inhibits CDK9 with an IC50 of <3 nM and has been characterized in preclinical rodent studies where it exhibits short in vivo half-lives. Intended for in vitro and early preclinical research use only.
- Potent CDK9 inhibition with IC50 <3 nM.
- Selective activity toward CDK9 for target validation studies.
- High supplied purity (≈99.94%), limiting impurity-related variability.
- Defined molecular properties (C27H35N5O2; MW 461.60 g·mol⁻1).
- Offered in multiple small-scale quantities suitable for preclinical experiments.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000743914 DAPTOMYCIN-D-ASN-D5 1MG
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