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Filtered Search Results
Enzo Life Sciences Geldanamycin (5mg). CAS: 30562-34-6
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Potent antitumor antibiotic. Inhibitor of pp60src tyrosine kinase and of c-myc gene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src, and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Capable of destabilizing several oncogene and proto-oncogene products. Potent inhibitor of the nuclear hormone receptor family. Protects against α-synuclein toxicity to dopaminergic neurons in Drosophila. Destabilizes mutant p53 protein from a number of breast, leukemic, and prostate cell lines. Inhibits basal and hypoxia-induced expression of c-Jun (IC50=75nM) and abolishes hypoxia-induced increase in c-Jun N-terminal kinase (JNK) activity. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO (10mg/ml); insoluble in water. Long Term Storage: -20°C.
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Enzo Life Sciences Aclacinomycin A, (5mg), CAS Number: 57576-44-0
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Originally identified as an anti-tumor drug, aclacinomycin A is the first described non-peptidic inhibitor showing discrete specificity for the chymotrypsin-like activity of the 20S proteasome. Aclacinomycin A has no effect on cathepsin B, it stimulates trypsin activity but inhibits the activity of both chymotrypsin and calpain. Alternative Name: Aclarubicin. Formula: C42H53NO15. MW: 811.9. CAS Number: 57576-44-0. Purity: ≥95% (TLC). Appearance: Yellow powder with orange cast. Solubility: Soluble in DMSO (25mg/ml) or dimethyl formamide (25mg/ml). Long Term Storage: -20°C
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Medchemexpress LLC HY-13582 100mg Medchemexpress, Carbendazim CAS:10605-21-7 Purity:>98%
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Medchemexpress, HY-13582 100mg Carbendazim CAS:10605-21-7 Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina. Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / EMD534085 / 1mg / 446264867 / HY-15000 / / 858668-07-2 / MFCD22628820 / 476.544 / C25H31F3N4O2
Medchem Express / EMD534085 / 1mg / 446264867 / HY-15000 / / 858668-07-2 / MFCD22628820 / 476.544 / C25H31F3N4O2
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Selleck Chemical LLC Eslicarbazepine Acetate S4657-20mg
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Eslicarbazepine Acetate (BIA 2093 Zebinix Exalief Stedesa Aptiom) an antiepileptic drug is a dual a dual Inhibitor of -Secretase and voltage-gated sodium channel
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![Medchemexpress LLC 6-[3,4-dihydroxy-pyrrolid-1-yl]-2-[3-hydroxy-3-methyl-pyrrolid-1-yl]-4-(CF3)pyridine-3-carbonitrile | 2135304-43-5 | 99.1% | 372.34 g·mol⁻1 | C16H19F3N4O3 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248560.png-250.jpg)
Medchemexpress LLC 6-[3,4-dihydroxy-pyrrolid-1-yl]-2-[3-hydroxy-3-methyl-pyrrolid-1-yl]-4-(CF3)pyridine-3-carbonitrile | 2135304-43-5 | 99.1% | 372.34 g·mol⁻1 | C16H19F3N4O3 | 100 MG
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KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with a reported IC50 of 0.45 μM, supplied as a high-purity small-molecule research compound suitable for enzymatic, cell-based, and in vivo studies.
- Potent KHK inhibition with IC50 0.45 μM.
- High purity, approximately 99.05% by COA.
- Highly soluble in DMSO (stock solutions up to 250 mg/mL).
- Formulation guidance provided for in vivo dosing.
- Powder storage: -20°C (3 years) or 4°C (2 years); in solvent: -80°C (2 years).
- Datasheet, COA, SDS, and LCMS documentation available for verification.
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Enzo Life Sciences Leptomycin B (100µg). CAS: 87081-35-4
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A potent and specific nuclear export inhibitor. Leptomycin B alkylates and inhibits CRM1/exportin 1, a protein required for nuclear export of proteins containing a nuclear export sequence (NES). In addition to antifungal and antibacterial activities, blocks the cell cycle and is a potent anti-tumor agent. At low nM concentrations, blocks the nuclear export of many proteins including HIV-1 Rev, MAPK/ERK, and NF-κB/IκB and it stabilizes the expression of p53. Other proteins that are influenced by leptomycin B are actin, c-Abl, cyclin B1, MDM2/p53, Iκb, MPF and PKA. Leptomycin B also inhibits the export and translation of many RNAs, including COX-2 and c-Fos mRNAs, by inhibiting export of ribonucleoproteins. Alternative name: LMB. Formulation: Solution in 100% ethanol. Purity: ≥96% (HPLC). Appearance: Liquid. Solubility: Soluble in methanol or 100% ethanol; insoluble in water. Unstable in DMSO. Long Term Storage: -20°C.
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Enzo Life Sciences R-Sulforaphane (10mg). CAS: 142825-10-3
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Potent, selective inducer of phase II detoxification enzymes. Inhibits chemically induced mammary tumor formation in rats. Alternative name: L-Sulforaphane, (-)-1-Isothiocyanato-4R-(methylsulfinyl)-butane. Purity: ≥98% (UHPLC). Solubility: Soluble in methanol, 100% ethanol, DMSO or ethyl acetate. Long Term Storage: -20°C.
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Medchemexpress LLC MMAF SODIUM 10MG
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5000204345 MMAF SODIUM 10MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380681 AG-1478 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383167 RIFAXIMIN-D6 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000427590 N6-METHYLADENOSINE 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430395 BLASTICIDIN S STERI 5ML
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568647 CLINDAMYCIN-ALCOHOLATE-5G
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Sigma Aldrich Fine Chemicals Biosciences Nalidixic acid >=98% | 389-08-2 | MFCD00006884 | 100G
Nalidixic acid >=98% | Purity: >=98% | Mol Wt: 232.24 | 389-08-2 | MFCD00006884 | 100G
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