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Filtered Search Results
Teknova Chloramphenicol 34mg/ml in Eth
Chloramphenicol 34mg/ml in Ethanol. 50mL, Sterile. 3/1170/II(L) - 1L limited 25 pack.
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Medchemexpress LLC Mal3-101 | 831217-40-4 | 98.2% | 931.12 | C54H66N4O10 | 5MG
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MAL3-101 is a small-molecule allosteric inhibitor of HSP70 used in research to inhibit HSP70 ATPase activity by disrupting Hsp40 co-chaperone interaction. It is supplied as a high-purity solid optimized for in vitro studies and has reliable storage and solubility characteristics for laboratory handling.
- Allosteric inhibitor of HSP70 that blocks Hsp40 interaction
- High purity suitable for in vitro research
- Molecular weight 931.12 and formula C54H66N4O10
- Off-white to light brown solid appearance
- Soluble in DMSO (≈50 mg/mL) with ultrasonic assistance
- Powder stable at -20°C for up to 3 years; in solvent recommended -80°C
- Applicable to studies of cancer cell proliferation and chaperone biology
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Medchemexpress LLC 6-(4-((5-chloro-4-((4-chlorophenyl)amino)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)-N-hydroxyhexanamide | 2284621-75-4 | 98.5% | 450.32 | C19H21Cl2N7O2 | 50MG
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JAK/HDAC-IN-1 is a small-molecule dual inhibitor of Janus kinases and histone deacetylases that exhibits low-nanomolar biochemical potency and antiproliferative, proapoptotic activity in hematological cell lines. The compound includes solubility and storage guidance for research applications and is provided as a high-purity research reagent.
- Dual JAK and HDAC inhibitory activity with low-nanomolar IC50s (example: JAK2 4 nM; HDAC 2 nM).
- Demonstrated antiproliferative and proapoptotic effects in hematological cell lines.
- Molecular formula C19H21Cl2N7O2; molecular weight 450.32.
- Soluble in DMSO (~20.83 mg/mL) and formulatable for in vivo dosing at ≥2.08 mg/mL in recommended vehicles.
- Storage: keep at 4°C protected from light; in solution store at -80°C (6 months) or -20°C (1 month) protected from light.
- Reported purity approximately 98.5%.
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Medchemexpress LLC Linezolid-d3 (PNU-100766-d3) | 1127120-38-0 | MFCD08063578 | >99.9% | 340.36 g/mol | C16H17D3FN3O4 | 1 MG
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Linezolid-d3 (PNU-100766-d3) is a deuterium-labeled analogue of the antibiotic linezolid designed for use as an isotopic internal standard and analytical reference in research and bioanalysis. It provides a defined mass shift for accurate quantitation by LC-MS/MS and other mass spectrometry methods.
- Deuterium-labeled internal standard for quantitative mass spectrometry.
- High chemical and isotopic purity (>99.9% reported).
- Molecular formula C16H17D3FN3O4 and molecular weight 340.36 g/mol.
- Available in milligram quantities suitable for method development and validation.
- Supplied as a neat solid for solution preparation and spiking workflows.
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BPS Bioscience Inc BPS BIOSCIENCE INC
NC3923110 CAS9 LNTVRS HYGROMYCIN 500X2
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Medchemexpress LLC Oligomycin A | HY-16589
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Oligomycin A
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Medchemexpress LLC Ribostamycin | 25546-65-0 | 99.9% | C17H34N4O10 | 50 MG
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Ribostamycin is a broad-spectrum aminoglycoside antibiotic effective against Gram-Negative and Gram-Positive bacterial infections. It also acts as an inhibitor of PDI chaperone activity.
- Broad-spectrum aminoglycoside antibiotic
- Effective against Gram-Negative and Gram-Positive bacterial infections
- Inhibits chaperone activity of PDI
- Targets bacterial processes and acts as an antibiotic
- Involved in anti-infection pathways
- Demonstrates in vitro inhibition of Borrelia burgdorferi and Escherichia coli
- Shows minimal nephrotoxicity in in vivo studies
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Medchemexpress LLC Rogocekib (CTX-712) | 2144751-78-8 | 98.2% | C19H17FN8O2 | 100 MG
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Rogocekib is an orally effective CLK 2 inhibitor with an IC50 of 1.4 nM, demonstrating anti-tumor activity. It is for research use only.
- Strong inhibitory effect on the proliferation of human myeloid K562 and MV-4-11 cells
- Exhibits anti-leukemia activity in primary acute myeloid leukemia (AML) cells
- Inhibits the phosphorylation of various serine/arginine (SR) proteins
- Reduces tumor size and increases survival rates in mouse models of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)
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Biotium NUCSPOT 568580 1000X 100UL
NUCSPOT 568580 1000X 100UL
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Medchemexpress LLC ZT-1a | 212135-62-1 | 99.8% | 445.73 | 100 MG
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ZT-1a is a potent, non-ATP-competitive, and selective SPAK inhibitor. It inhibits SPAK activity and decreases SPS1-related proline/alanine-rich kinase (SPAK)-dependent phosphorylation of Na-K-2Cl cotransporter (NKCC1) and K-Cl cotransporters (KCCs).
- Potent, non-ATP-competitive, and selective SPAK inhibitor
- Inhibits SPAK activity with IC50s of 44.3, 35.0, and 46.7 μM
- Inhibits Na-K-2Cl cotransporter (NKCC1)
- Stimulates K-Cl cotransporters (KCCs)
- Decreases SPAK-dependent phosphorylation
- For research use only
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Medchemexpress LLC Fingolimod (FTY720 free base) | 162359-55-9 | MFCD09262100 | 99.97% | 308.4 | 50 MG
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Fingolimod (FTY720 free base) is a brain-penetrant sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also acts as a PAK1 activator and an immunosuppressant. It is for research use only.
- Brain-penetrant sphingosine 1-phosphate (S1P) antagonist
- IC50 of 0.033 nM in K562 and NK cells
- PAK1 activator
- Immunosuppressant
- For research use only
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Enzo Life Sciences Staurosporine (5mg). CAS: 62996-74-1
Model apoptosis inducer. Potent cell-permeable inhibitor of a variety of protein kinases, e.g. protein kinase C (PKC), CDK1/cyclin B (IC50~5nM), CDK2/cyclin A (IC50=7nM), CDK4/cyclin D (IC50=3-10µM), CDK5/p25 (IC50=4nM), GSK-3β (IC50=15nM), Pim-1 kinase (IC50=10nM).Binds do the ATP binding domain. Did not inhibit PKC-ζ. At 1µM induced apoptosis in CHO cells. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site tyrosine. Alternative name: Antibiotic AM-2282. Purity: ≥99% (HPLC). Appearance: Off-white to green powder. Solubility: Soluble in ethyl acetate, DMSO (25mg/ml) or dimethyl formamide (25mg/ml); only slightly soluble in chloroform and methanol. Insoluble in water. Long Term Storage: +4°C.
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Enzo Life Sciences Gramicidin A (5 mg) CAS: 11029-61-1
Ionophore antibiotic. Naturally occurring ion channel forming pentadecapeptide. Causes K+/H+-exchange in mitochondria in a non-voltage dependent manner. Formula: C99H140N20O17. MW: 1882.3. CAS: 11029-61-1. MI: 14: 4532. Purity: ≥90% (HPLC). Sequence HCO-Val-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCH2CH2OH. Appearance: White to off-white powder. Solubility: Soluble in DMSO, lower alcohols or acetic acid. Long Term Storage: -20°C
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Selleck Chemical LLC Anisomycin
Anisomycin (Flagecidin Wuningmeisu C) is a bacterial antibiotic isolated from Streptomyces griseolus which inhibits protein synthesis and also act as a JNK activator Anisomycin upregulates autophagy and increases apoptosis
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Selleck Chemical LLC Marimastat
Marimastat (BB-2516 TA2516) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-9 MMP-1 MMP-2 MMP-14 and MMP-7 with IC50 of 3 nM 5 nM 6 nM 9 nM and 13 nM respectively Phase 3
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