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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Blasticidin S Ready Made Solution, 1 mL
Blasticidin S belongs to the aminoacylnucleoside class of antibiotics. It inhibits protein synthesis in bacteria and eukaryotes. It also has fungicidal properties and prevents rice blast disease. Blasticidin S inhibits hydrolysis of peptidyl-tRNA induced by release factors. It enhances the binding of tRNA to the large subunit of ribosomes and to an extent inhibits peptide bond formation.
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Medchemexpress LLC HY-50737A 5mg Medchemexpress, DUB-IN-2 CAS:924296-19-5 Purity:>98%
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Medchemexpress, HY-50737A 5mg DUB-IN-2 CAS:924296-19-5 DUB-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100828 5mg Medchemexpress, BGP-15 CAS:66611-37-8 Purity:>98%
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Medchemexpress, HY-100828 5mg BGP-15 CAS:66611-37-8 BGP-15 is a PARP inhibitor, with an IC 50 and a K i of 120 and 57 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Trospium chloride 10405-02-4 25mg
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Trospium chloride (CAS 10405-02-4) is a quaternary ammonium compound that functions as a competitive antagonist at muscarinic acetylcholine receptors thereby inhibiting cholinergic stimulation of the bladder detrusor muscle This action reduces involuntary bladder contractions leading to decreased urinary urgency frequency and urge incontinence Trospium chloride displays pharmacological properties distinct from tertiary amine antimuscarinics including limited central nervous system penetration It is widely utilized in preclinical and clinical research focused on urinary disorders and muscarinic receptor pharmacology
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Medchemexpress LLC NVP 231 | 362003-83-6 | 99.7% | 431.55 | 500 MG
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NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor with an IC50 of 12 nM, which competitively inhibits the binding of ceramide to CerK. It induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage.
- Potent, specific, and reversible CerK inhibitor.
- IC50 of 12 nM for CerK.
- Competitively inhibits ceramide binding to CerK.
- Induces cell apoptosis.
- Reduces cellular CerK activity (IC50: 59.70 ± 12 nM).
- Decreases cell viability dose-dependently.
- Induces caspase-3 and caspase-9 cleavage and activation.
- Upregulates cyclin B1 phosphorylation at Ser133.
- Reduces CDK1 phosphorylation at Tyr15.
- Total CDK1 expression declined.
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eMolecules 88191-84-8 | Medchem Express | MDL-28170 | 5mg | 441682011 | HY-18236 | MFCD29055381 | 382.46 | C22H26N2O4
Medchem Express | MDL-28170 | 5mg | 441682011 | HY-18236 | 88191-84-8 | MFCD29055381 | 382.460 | C22H26N2O4
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Research Products International Corp G-418 Disulfate 50 mg/ml Solution, 20 Milliliters
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G-418 Disulfate, also known as Geneticin, is an aminoglycoside antibiotic derived from Micromonospora rhodorangea. It is widely used in molecular biology and cell culture as a selective agent. G-418 inhibits protein synthesis by targeting the 80S ribosome, blocking translocation. It is commonly used to select genetically modified cells that carry a G-418 resistance gene, typically introduced via plasmid vectors. This allows for the isolation and maintenance of stable transfectants in gene expression, protein production, and cell line development studies. Its selectivity makes it a key tool in genetic engineering.
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Medchemexpress LLC HY-19312 100mg Medchemexpress, 3-Methyladenine CAS:5142-23-4 Purity:>98%
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Medchemexpress, HY-19312 100mg 3-Methyladenine CAS:5142-23-4 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Kd Medical Inc AMPICILLIN SOLUTION 100MG/ML
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For selection for ampicillin resistance in mutated and transformed cells. One 10ml bottle.
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Research Products International Corp Doxorubicin Hydrochloride, Liquid, 10 Milligrams
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Doxorubicin HCl is an anthracycline antibiotic. Doxorubicin works by interfering with the DNA in cells, preventing the synthesis of new DNA and RNA. It does this by intercalating between DNA base pairs, causing breaks in the DNA strands, and inhibiting the activity of topoisomerase II, an enzyme involved in DNA replication.
Ultimately, these actions lead to the inhibition of cell division and cell death.
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Abcam Rapamycin, mTORC1 comple x inhibitor, 1MG
MW 914.2 Da, Purity >98%. Immunosuppressant and antifungal agent . Complexes with FKBP-12 and inhibits mTOR (mammalian target of rapamycin). In complex with its cellular receptor, the FK506-binding protein (FKBP12), rapamycin binds and inhibits the function of the mammalian target of rapamycin (mTOR).
The product is subject to the following: Abcam Restricted Use Statement
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Apexbio Technology LLC Valinomycin 2001-95-8 25mg
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Valinomycin (CAS 2001-95-8) is a small-molecule potassium ionophore targeting potassium ion transport It is designed to facilitate selective potassium ion translocation across lipid membranes thereby disrupting intracellular potassium homeostasis Valinomycin exerts its biological activity primarily through passive transport of potassium ions leading to mitochondrial membrane depolarization and induction of apoptotic pathways In in vitro studies using Chinese hamster ovary (CHO) cells valinomycin induces apoptosis within 12 hours of exposure with an IC50 value around or below 1 M in cell-based assays Based on these pharmacological properties valinomycin holds research potential in studies of mitochondrial-mediated apoptosis and ion homeostasis
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Medchemexpress LLC 1-(6,7-dichloro-9-(1-methyl-1H-pyrazol-3-yl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)-2-hydroxyethanone | 2369751-07-3 | MFCD34368516 | 99.2% | C17H16Cl2N4O2 | 10MG
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G140 is a small-molecule research inhibitor of cyclic GMP-AMP synthase (cGAS) used to investigate innate immune and inflammatory signaling. It is potent against human cGAS (IC50 14.0 nM) and shows activity against mouse cGAS (IC50 442 nM), and is provided as a high-purity compound for in vitro studies.
- Potent, selective inhibition of cGAS in human assays.
- IC50 14.0 nM for human cGAS and 442 nM for mouse cGAS.
- High purity suitable for biochemical and cell-based assays.
- Supplied as a small-molecule solid for in vitro research.
- Enables study of the cGAS-STING pathway and inflammatory responses.
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Research Products International Corp Cefoperazone, Sodium Salt, 5 Grams
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Cefoperazone Sodium Salt is a third-generation cephalosporin antibiotic. Cefoperazone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This disruption interferes with the final stages of peptidoglycan synthesis in the bacterial cell wall, leading to structural instability and eventual cell lysis.
Cefoperazone is effective against a broad range of bacteria, both Gram-positive and Gram-negative. Cefoperazone Sodium Salt is often used as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Its inclusion allows for the specific growth of bacteria lacking resistance to cefoperazone.
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Sigma Aldrich Fine Chemicals Biosciences Moxifloxacin hydrochloride United States Pharmacopeia (USP) Reference Standard | 186826-86-8 | MFCD00949117 | 200MG
Moxifloxacin hydrochloride United States Pharmacopeia (USP) Reference Standard | Mol Wt: 437.89 | 186826-86-8 | MFCD00949117 | 200MG
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