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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Polymyxin B sulfate salt | 1405-20-5 | MFCD00131991 | 25MU
Polymyxin B sulfate salt | Mol Wt: 1385.61 | 1405-20-5 | MFCD00131991 | 25MU
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eMolecules 959122-11-3 | Medchem Express | A 922500 | 5mg | 446255301 | HY-10038 | MFCD12828780 | 428.488 | C26H24N2O4
Medchem Express | A 922500 | 5mg | 446255301 | HY-10038 | 959122-11-3 | MFCD12828780 | 428.488 | C26H24N2O4
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Medchemexpress LLC HY-104028 5mg Medchemexpress, BAY 73-6691 CAS:794568-92-6 Purity:>98%
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Medchemexpress, HY-104028 5mg BAY 73-6691 CAS:794568-92-6 BAY 73-6691 is a potent, selective brain penetrant PDE9A inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC TTA-A2 | 953778-63-7 | MFCD16628062 | 99.3% | 378.39 g/mol | C20H21F3N2O2 | 5 MG
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TTA-A2 is a potent, selective, orally active T-type voltage-gated calcium channel antagonist used in preclinical neuroscience research. It shows low-nanomolar potency against Cav3.1 and Cav3.2 channels and is supplied as a high-purity solid for laboratory use.
- Potent T-type calcium channel antagonist (IC50 ≈ 89-92 nM).
- Low-nanomolar potency against Cav3.1 and Cav3.2.
- High purity (~99.3%).
- Molecular weight 378.39 g/mol; formula C20H21F3N2O2.
- Solid form; powder stable at -20°C for up to 3 years.
- In solvent: stable at -80°C for 6 months or -20°C for 1 month.
- Intended for research use in studies of sleep disorders, epilepsy, and related neurological models.
- Available in small-mass quantities for in vitro and in vivo experiments.
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Supply Solutions RAPAMICINA 200UL
RapamycinReady Made Solution, 2.5 mg/mL in DMSO (2.74 mM)
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Gold Biotechnology Inc Rapamycin 100 mg
Rapamycin is a macrolide antibiotic isolated from Streptomyces hygroscopicus It has been shown to display anticancer activity such as induction of apoptosis and inhibition of angiogenesis and proliferation in tumor cell lines Rapamycin is also an immunosuppressant and FRAP inhibitor and inhibits lymphokine-induced cell proliferation
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eMolecules 910484-28-5 | Medchem Express | TTA-Q6 | 5mg | 415686505 | HY-10388 | 405.81 | C20H15ClF3N3O
Medchem Express | TTA-Q6 | 5mg | 415686505 | HY-10388 | 910484-28-5 | 405.810 | C20H15ClF3N3O
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Medchemexpress LLC Erythromycin-13C2 | 202114-52-1 | 5 MG
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Erythromycin-13C2 is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC Gcn2-in-6 (compound 6d) | 2183470-09-7 | 98.9% | C19H12Cl2F2N4O3S | 10MG
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GCN2-IN-6 is a small-molecule inhibitor of the eIF2α kinase GCN2 used as a research tool to probe the integrated stress response and related signaling pathways. It has been characterized in enzymatic and cellular assays and is provided for laboratory research in solid and DMSO solution formats.
- Potent GCN2 inhibitor with enzymatic IC50 ~1.8 nM and cellular IC50 ~9.3 nM.
- Also shows activity against PERK in enzymatic and cellular assays.
- High nominal purity (~98.9% as listed on product page).
- Molecular formula C19H12Cl2F2N4O3S; molecular weight 485.29.
- Available as mg-scale solid and 10 mM DMSO solutions for convenient use.
- CAS 2183470-09-7 for unambiguous chemical identification.
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Medchemexpress LLC HY-17409 500mg , Nystatin CAS:1400-61-9 Purity:>98%
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HY-17409 500mg Nystatin CAS: 1400-61-9 Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion. Nystatin is a cholesterol-sequestering agent, partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis[5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Erythromycin, 2'-propanoate, dodecyl sulfate (1:1) | 3521-62-8 | 50 MG
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Erythromycin estolate is a macrolide antibiotic derivative that is used to treat various bacterial infections. Intended for research use only, it has been noted to cause liver injury, primarily cholestatic hepatitis, and inhibits several flaviviruses such as Zika and dengue viruses, and human coronavirus OC43.
- Macrolide antibiotic derivative
- Used to treat various bacterial infections
- Causes liver injury, primarily cholestatic hepatitis
- Inhibits several flaviviruses including Zika virus, dengue virus, yellow fever virus, and human coronavirus OC43
- Inactivates viral particles by compromising the integrity of the viral membrane
- Reduces virus titer of HCoV-OC43 with an IC50 of 1.40 μM
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Medchemexpress LLC Roxithromycin | 80214-83-1 | 1 G
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Roxithromycin (RU-28965) is an orally active semi-synthetic macrolide antibiotic. It inhibits protein biosynthesis in the elongation step by binding to the 50S bacterial ribosome. Roxithromycin exhibits antimicrobial, antiproliferative, anti-inflammatory, tumor vasculature inhibiting, and lung injury ameliorating effects.
- Inhibits protein biosynthesis by binding to 50S bacterial ribosome
- Active against Gram-positive and Gram-negative bacteria
- Displays antimicrobial, antiproliferative, and anti-inflammatory effects
- Inhibits tumor vasculature and ameliorates lung injury
- Reduces UVB-induced oxidative stress and keratinocyte apoptosis
- Induces apoptosis in senescent cells
- Protects against various bacterial infections in vivo
- Inhibits tumor angiogenesis and attenuates lung injury in animal models
- Modulates NF-κB and MAPK/ERK pathways
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eMolecules 497839-62-0 | Medchem Express | AEE788 | 5mg | 446255491 | HY-10045 | 440.595 | C27H32N6
Medchem Express | AEE788 | 5mg | 446255491 | HY-10045 | 497839-62-0 | 440.595 | C27H32N6
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Medchemexpress LLC HY-11010 5mg Medchemexpress, AS601245 CAS:345987-15-7 Purity:>98%
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Medchemexpress, HY-11010 5mg AS601245 CAS:345987-15-7 AS601245 is a cell-permeable JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Bafilomycin A1, 1 Milligram
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Bafilomycin A1 is a potent and selective inhibitor of the vacuolar-type H+-ATPase (V-ATPase), an enzyme responsible for maintaining acidic pH in cellular compartments such as lysosomes and endosomes.
In the life science field, Bafilomycin A1 is primarily used as a research tool to investigate the role of V-ATPase and lysosomal acidification in various cellular processes. By inhibiting V-ATPase, Bafilomycin A1 disrupts the acidification of cellular compartments, which in turn affects processes such as protein degradation, autophagy, endocytosis, and vesicular trafficking.
Bafilomycin A1 can be used to study autophagy, a cellular process involved in the degradation and recycling of cellular components. By inhibiting V-ATPase, Bafilomycin A1 blocks the final step of autophagy, preventing the fusion of autophagosomes with lysosomes and thereby inhibiting autophagic degradation.
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