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Filtered Search Results
Medchemexpress LLC BRL-15572 dihydrochloride | 193611-72-2 | 99.8% | 479.87 | C25H29Cl3N2O | 5 MG
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BRL-15572 dihydrochloride is a selective antagonist of the human 5-HT1D receptor supplied for research use. The compound is available as a solid in multiple pack sizes and as a 10 mM solution in DMSO, and is characterized by manufacturer-provided analytical data including molecular weight and purity.
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Medchemexpress LLC HY-113046 50mg Medchemexpress, 5-Methyltetrahydrofolic acid CAS:134-35-0 Purity:>98%
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Medchemexpress, HY-115560A 10mg Thalidomide-O-amido-C3-NH2 (TFA) CAS:2022182-58-5 Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences 5-Fluorocytosine nucleoside analog | 2022-85-7 | MFCD00006035 | 1g
5-Fluorocytosine nucleoside analog | Purity: 99% | MW: 129.09 | 2022-85-7 | MFCD00006035 | 1g
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Medchemexpress LLC HY-B0958 50mg , Mupirocin BRL-4910A;Pseudomonic acid CAS:12650-69-0 Purity:98%
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Medchemexpress, HY-B0958 50mg Mupirocin BRL-4910A;Pseudomonic acid CAS:12650-69-0 Formula:C26H44O9 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15463 5g , Imatinib STI571 CAS:152459-95-5 Purity:98%
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Medchemexpress, HY-15463 5g Imatinib STI571 CAS:152459-95-5 Formula:C29H31N7O IC50: ~100 nM (c-Kit, Bcr-Abl, and PDGFR) Purity:98% Imatinib is a known inhibitor of the c-Kit , Bcr-Abl , and PDGFR tyrosine kinases, inhibits the SLF-dependent activation of c-Kit wt kinase with IC 50 of ~100 nM, which is similar to the concentration requires for inhibition of Bcr-Abl and PDGFR. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Research Products International Corp Puromycin, 1 G
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Puromycin Dihydrochloride is a potent antibiotic. It is an amino nucleoside antibiotic that mimics the 3'-end of aminoacyl-tRNA. It enters the ribosomal A site during translation, causing premature chain termination and inhibiting protein synthesis. Puromycin is incorporated into growing polypeptide chains, leading to the release of incomplete and nonfunctional peptides.
Widely used as a tool in cell biology to study protein synthesis and investigate translation processes. Its ability to terminate protein synthesis at the ribosome makes it valuable for various applications, including pulse-chase experiments and the analysis of nascent peptides. Puromycin resistance genes are often used as selectable markers in genetic engineering. Cells expressing the resistance gene can survive and proliferate in the presence of Puromycin, allowing for the selection of transfected or transduced cells.
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eMolecules 1397219-81-6 | BS-181 HCl | MFCD18384975 | 50mg
Ambeed | 24-Dichloronicotinonitrile | 1g | 525050890 | A141567 | 180995-12-4 | MFCD09750302 | 173.000 | C6H2Cl2N2
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Medchemexpress LLC Lomeguatrib | 192441-08-0 | 99.8% | 326.17 | 100 MG
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Lomeguatrib is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor. It exhibits an IC50 of 9 nM in cell-free assays and 6 nM in MCF-7 cells.
- Acts as an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor.
- Shows an IC50 of 9 nM in cell-free assays.
- Exhibits an IC50 of 6 nM in MCF-7 cells.
- Increases the growth inhibitory effects of temozolomide in MCF-7 cells.
- Completely inactivates MGMT within 2 hours at 20 mg/kg i.p.
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Medchemexpress LLC (1R,2S)-VU0155041 | 1093757-42-6 | 99.1% | 316.18 g/mol | C14H15Cl2NO3 | 5 MG
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VU0155041 is a research-grade small molecule that functions as a potent, selective positive allosteric modulator (PAM) of metabotropic glutamate receptor 4 (mGluR4). It has reported sub-micromolar activity and is supplied as a high-purity solid suitable for in vitro pharmacology and preclinical studies.
- Potent, selective positive allosteric modulator of mGluR4 (EC50 ≈ 798 nM human, 693 nM rat).
- High purity: 99.1%.
- Molecular weight: 316.18 g/mol.
- Soluble in DMSO at 100 mg/mL.
- Supplied as a 5 mg solid for laboratory use.
- Applicable to preclinical research, including Parkinson's disease models.
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Selleck Chemical LLC NE 52-QQ57
NE 52-QQ57 is a selective and orally available antagonist of G-protein coupled receptor 4 (GPR4) with IC50 of 0 07 M NE 52-QQ57 effectively blocks GPR4-mediated cAMP accumulation with IC50 of 26 8 nM in HEK293 cells The antagonism of GPR4 with NE 52-QQ57 significantly inhibits the AGE-induced increased expression of several key inflammatory cytokines and signaling molecules including tumor necrosis factor- (TNF- ) interleukin (IL)-1 IL-6 inducible nitric oxide synthase (iNOS) nitric oxide (NO) cyclooxygenase 2 (COX2) and prostaglandin E2 (PGE2)
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Medchemexpress LLC Acyclovir-d4 (Aciclovir-d4) | 1185179-33-2 | 98.7% | 229.23 | 5 MG
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Acyclovir-d4 is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. It inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination. Acyclovir also prevents bacterial infections during induction therapy for acute leukaemia.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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eMolecules 7177-48-2 | AstaTech | AMPICILLIN TRIHYDRATE | 50g | 392632363 | 42357 | 95 | MFCD00072036 | 403.45 | C16H25N3O7S
AstaTech | AMPICILLIN TRIHYDRATE | 50g | 392632363 | 42357 | 95.000 | 7177-48-2 | MFCD00072036 | 403.450 | C16H25N3O7S
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Medchemexpress LLC HY-101422 5mg Medchemexpress, GAL-021 CAS:1380341-99-0 Purity:>98%
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Medchemexpress, HY-101422 5mg GAL-021 CAS:1380341-99-0 GAL-021 a new intravenous BKCa-channel blocker. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100224 10mg Medchemexpress, SANT-1 CAS:304909-07-7 Purity:>98%
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Medchemexpress, HY-100224 10mg SANT-1 CAS:304909-07-7 SANT-1 is a potent Smo antagonist, inhibits Hedgehog signaling, with IC50s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 assay, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 878739-06-1 | Medchem Express | AZ 628 | 5mg | 446259741 | HY-11004 | MFCD17392577 | 451.53 | C27H25N5O2
Medchem Express | AZ 628 | 5mg | 446259741 | HY-11004 | 878739-06-1 | MFCD17392577 | 451.530 | C27H25N5O2
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