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Filtered Search Results
Medchemexpress LLC HY-19807 5mg Medchemexpress, Indirubin-3'-monoxime CAS:160807-49-8 Purity:>98%
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Medchemexpress, HY-19807 5mg Indirubin-3'-monoxime CAS:160807-49-8 Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 1,4-bis(4,5-diphenyl-1H-imidazol-2-yl)benzene | 4051-59-6 | MFCD00231029 | 98.0% | 514.62 g·mol⁻¹ | C36H26N4 | 50 MG
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MSX-130 is a small-molecule CXCR4 antagonist for preclinical research, reported to inhibit cancer metastasis. It is supplied as a solid with high purity and recommended for in vitro studies using DMSO preparations.
- Targets CXCR4 and inhibits cancer metastasis.
- High purity (98.0%) suitable for biochemical assays.
- Soluble in DMSO at approximately 2 mg/mL with sonication and warming.
- Powder stable at -20°C for extended storage; solutions require low-temperature storage for long-term stability.
- Supplied as a 50 mg solid for laboratory research use.
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Medchemexpress LLC Crbn modulator-1 | 2407829-65-4 | MFCD33029299 | 98.0% | C17H12N2O5 | 10MG
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CRBN modulator-1 is a thalidomide analog that modulates cereblon (CRBN), an E3 ligase substrate receptor. Described in WO2020006262A1 (compound 10), the compound has reported biochemical activity (IC50 3.5 μM; Ki 0.98 μM) and is supplied as a solid for research use with supporting analytical documentation.
- Acts as a cereblon modulator with IC50 3.5 μM and Ki 0.98 μM.
- Provided as a solid powder suitable for research applications.
- High purity, 98.0%, with supporting analytical data available.
- Molecular formula C17H12N2O5; molecular weight 324.29 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Documentation includes datasheet, certificate of analysis, NMR, HPLC, and MS.
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Selleck Chemical LLC Azathramycin S4978-25mg
Azathramycin (Azaerythromycin A Azaerythromycin) is a macrolide antibiotic containing cladinose
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Enzo Life Sciences Duvelisib (free base) (100mg). CAS: 1201438-56-3
Duvelisib is an orally bioavailable and highly selective inhibitor of PI3K-δ and PI3K-γ with IC50 values of 0.36 nM and 19.6 nM, respectively. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
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Chem-Impex International, Inc. Cefmetazole sodium salt | MFCD00214260 | 1G
Cefmetazole sodium salt, MFCD00214260, 1G
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eMolecules 83905-01-5 | Azithromycin | Medchem Express | MFCD03266623 | 748.996 | C38H72N2O12 | 98.000 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O | 100mg | 4462...
Azithromycin | Medchem Express | 83905-01-5 | MFCD03266623 | 748.996 | C38H72N2O12 | 98.000 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O | 100mg | 446268549
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Medchemexpress LLC Asymmetric-dimethylarginine-d6 dihydrochloride | 1313730-20-9 | 99.5% | 281.21 | 1 MG
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Asymmetric-dimethylarginine-d6 (dihydrochloride) is the deuterium labeled Asymmetric-dimethylarginine dihydrochloride. This product is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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eMolecules 1094067-13-6 | Medchem Express | SCH-1473759 (hydrochloride) | 2mg | 446258729 | HY-10483 | MFCD18251447 | 463 | C20H27ClN8OS
Ambeed | 3-Iodo-1H-pyrazolo[34-b]pyridine | 1g | 490540700 | A236030 | 117007-52-0 | MFCD09749818 | 245.023 | C6H4IN3
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Medchemexpress LLC HY-108585A 10mg Medchemexpress, VU591 CAS:1222810-74-3 Purity:>98%
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Medchemexpress, HY-108585A 10mg VU591 CAS:1222810-74-3 VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Carboxyamidotriazole orotate | 187739-60-2 | 99.7% | 580.76 | 50 MG
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Carboxyamidotriazole Orotate is an orally bioavailable signal transduction inhibitor. It acts as a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways, demonstrating anti-tumor, anti-inflammatory, and antiangiogenic effects.
- Inhibits cell proliferation in specific leukemia cell lines.
- Reduces phosphorylation of Bcr-Abl kinase targets.
- Induces a 50% growth reduction in chronic myelogenous leukemia (CML) cell lines.
- Demonstrates dose-dependent inhibition of Bcr-Abl levels.
- Exhibits antitumor activity in CML xenografts, leading to increased survival.
- Has been evaluated in multiple clinical trials for various cancers.
- Intended for research use only.
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Medchemexpress LLC HY-108690 10mg Medchemexpress, Fluxametamide CAS:928783-29-3 Purity:>98%
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Medchemexpress, HY-108690 10mg Fluxametamide CAS:928783-29-3 Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Dalcetrapib (JTT-705) S2772-5mg
Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0 2 M that increases the plasma HDL cholesterol Phase 3
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Apexbio Technology LLC Roxithromycin 80214-83-1 10mM (in 1mL DMSO)
Roxithromycin (80214-83-1) is a semisynthetic macrolide antibiotic that acts by binding to the bacterial ribosomal 50S subunit thereby inhibiting peptide chain elongation and disrupting protein synthesis Roxithromycin exerts its biological activity primarily through this mechanism of action In both in vitro and in vivo models Roxithromycin demonstrates inhibitory effects on cell proliferation inflammation pathways and tumor angiogenesis Reported IC50 values typically vary depending on the cell type and assay methodology Based on these pharmacological properties Roxithromycin holds research potential in studies of inflammation-associated pathologies cancer biology and lung injury
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eMolecules 891494-64-7 | Medchem Express | SCH900776 (S-isomer) | 5mg | 446265908 | HY-15532B | MFCD23135227 | 376.262 | C15H18BrN7
Medchem Express | SCH900776 (S-isomer) | 5mg | 446265908 | HY-15532B | 891494-64-7 | MFCD23135227 | 376.262 | C15H18BrN7
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