Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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5,281 – 5,295 of 6,971 results

5,281

Aat Bioquest GTTR [Texas Red gentamicin conjugate] (100 ug)

Gentamicin is widely used for treating tuberculosis and Gram-negative infections and is particularly useful in neonatal intensive care units. This catalog is for 100 ug.

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5,282

APEXBIO TECHNOLOGY LLC FT-207 (NSC 148958) 17902-23-7 100mg

FT-207 (NSC 148958 CAS 17902-23-7) also known as tegafur or ftorafur is an orally administered prodrug of 5-fluorouracil (5-FU) Upon metabolic activation FT-207 releases 5-FU which inhibits thymidylate synthase and disrupts DNA synthesis thereby exhibiting cytotoxic effects on proliferating cells FT-207 is utilized in oncology research as a representative agent for studying fluoropyrimidine-based chemotherapy including combination regimens such as tegafur-uracil Its pharmacokinetic profile and conversion mechanism make it relevant for investigating prodrug strategies and anticancer therapeutics in preclinical models

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5,283

Apexbio Technology LLC Betamipron 3440-28-6 50mg

Betamipron (CAS 3440-28-6) is a small-molecule inhibitor targeting renal tubular uptake mechanisms It is designed to inhibit renal tubular uptake thereby reducing nephrotoxicity during carbapenem antibiotic therapy Betamipron exerts its biological activity primarily through blockade of the renal tubular uptake process Its potency is typically assessed via renal uptake assays and cellular transporter inhibition tests however exact IC50 values depend on experimental conditions and models and are not explicitly provided Based on these pharmacological properties Betamipron holds research potential in the investigation of antibiotic-related renal pharmacokinetics carbapenem distribution profiles and nephrotoxic side-effects

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5,284

APEXBIO TECHNOLOGY LLC Nateglinide 105816-04-4 10mg

Nateglinide (CAS 105816-04-4) is a synthetic oral antihyperglycemic agent classified within the meglitinide class It functions as an insulin secretagogue by selectively binding to pancreatic -cell ATP-dependent potassium channels resulting in membrane depolarization and subsequent stimulation of insulin release Nateglinide is widely employed in research focused on non-insulin-dependent diabetes mellitus providing a tool for investigating glucose-stimulated insulin secretion -cell responsiveness and the pharmacological modulation of insulinotropic pathways in metabolic disease models

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5,285

Apexbio Technology LLC Bacitracin Zinc 1405-89-6 50mg

Bacitracin Zinc (CAS 1405-89-6) is a peptide antibiotic targeting the dephosphorylation of C55-isoprenyl pyrophosphate It is designed to inhibit this step thereby disturbing bacterial cell wall biosynthesis Bacitracin Zinc exerts its biological activity primarily by interfering with the dephosphorylation process It also inhibits the enzymatic cleavage of tyrosine from Met-enkephalin with an IC50 value of approximately 10 M Based on these pharmacological properties Bacitracin Zinc holds research potential in studying bacterial cell envelope biosynthesis enzymatic processes involving peptide substrates and enzyme assay development in biomedical investigations

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5,286

Apexbio Technology LLC 3CAI 28755-03-5 5mg

3CAI (CAS 28755-03-5) is a small molecule allosteric inhibitor selectively targeting AKT serine/threonine kinases Acting via an ATP-noncompetitive mechanism 3CAI binds directly to AKT1 and AKT2 exhibiting an IC50 of 1 M and suppressing 60% of AKT1 kinase activity at this concentration In vitro 3CAI reduces the expression of downstream AKT targets such as mTOR and GSK3 and at 4 M induces growth inhibition and apoptosis in HCT116 and HCT29 colon cancer cells Oral administration at 30 mg/kg significantly inhibits tumor growth and AKT substrate expression in mouse xenograft models 3CAI is valuable for studying AKT signaling and its implications in cancer research

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5,287

APEXBIO TECHNOLOGY LLC Oxybutynin chloride 1508-65-2 100mg

Oxybutynin chloride (CAS 1508-65-2) is a synthetic antimuscarinic agent that functions primarily by inhibiting the action of acetylcholine on muscarinic receptors in smooth muscle particularly within the bladder This antagonism results in reduced involuntary detrusor muscle contractions thereby modulating urinary urgency and frequency In biomedical research oxybutynin chloride is employed to investigate cholinergic pathways involved in bladder function neurogenic bladder disorders and the pharmacological modulation of muscarinic signaling in urinary physiology

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5,288

Medchemexpress LLC HY-N0565B 5g , Doxycycline (hyclate) CAS:24390-14-5 Purity:>98%

HY-N0565B 5g Doxycycline (hyclate) CAS: 24390-14-5 Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity[4][5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,289

Medchemexpress LLC HY-P1975 5mg , Aureobasidin A CAS:127785-64-2 Purity:>98%

HY-P1975 5mg Aureobasidin A CAS: 127785-64-2 Aureobasidin A (Basifungin), a cyclic depsipetide, is an antifungal antibiotic. Aureobasidin A (Basifungin) A is an inhibitor of the inositolphosphorylceramide synthase AUR1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,290

Medchemexpress LLC HY-10373 5mg , Trimetrexate CAS:52128-35-5 Purity:>98%

HY-10373 5mg Trimetrexate CAS: 52128-35-5 Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer[4][5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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5,291

EAGLE BIOSCIENCES INC Plasmid Residual DNA (Kanamycin Resistance Gene) Detection Kit (qPCR)

Plasmid Residual DNA (Kanamycin Resistance Gene) Detection Kit (qPCR)

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5,292

APEXBIO TECHNOLOGY LLC Clindamycin Phosphate 24729-96-2 50mg

Clindamycin Phosphate (CAS 24729-96-2) is a prodrug derivative of clindamycin from the lincosamide antibiotic class It is designed to undergo enzymatic hydrolysis in vivo to release active clindamycin which inhibits bacterial protein synthesis by binding to ribosomal subunits exerting bacteriostatic effects Clindamycin Phosphate exhibits no direct antibacterial activity in vitro but demonstrates bacteriostatic activity upon hydrolysis to clindamycin Reported IC50 values of clindamycin against sensitive bacterial strains are typically in the low micromolar concentration range Based on these pharmacological properties Clindamycin Phosphate holds research potential in studies focused on microbial pathogens associated with skin infections acne and bacterial vaginosis It has also been assessed in combination strategies such as coupling with platelet-rich fibrin (PRF) to enhance antibacterial capacity without observable cytotoxicity

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5,293

Apexbio Technology LLC Clindamycin 18323-44-9 100mg

Clindamycin (CAS 18323-44-9) is a small-molecule inhibitor targeting the bacterial 50S ribosomal subunit It is designed to disrupt peptide bond formation during protein synthesis thereby inhibiting bacterial proliferation Clindamycin exerts its biological activity primarily through binding to the 50S ribosomal subunit which interrupts peptide elongation and protein assembly In biochemical research Clindamycin demonstrates antimicrobial inhibition with reported IC50 values typically in the low micromolar range depending on bacterial strains and experimental conditions Based on these pharmacological properties Clindamycin holds research potential in microbiological and pharmacological studies for evaluating antimicrobial susceptibility bacterial ribosomal functions and mechanisms of antibiotic resistance

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5,294

APEXBIO TECHNOLOGY LLC Streptomycin sulfate 3810-74-0 10mM (in 1mL H2O)

Streptomycin sulfate is an aminoglycoside antibiotic targeting the bacterial 30S ribosomal subunit It is designed to inhibit bacterial protein synthesis thereby suppressing bacterial proliferation Streptomycin sulfate exerts its biological activity primarily through inhibition of mRNA translation by binding to the 30S subunit which impairs initiation and elongation processes during protein synthesis and disrupts the ribosome mRNA complex Based on these pharmacological properties streptomycin sulfate holds research potential in microbiological experimentation susceptibility assays bacterial resistance profiling microbial genetics studies and screening of transgenic cells expressing antibiotic-resistance markers

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5,295

STA PHARMACEUTICAL US LLC Fmoc-Gabapentin | 100 g | CAS 882847-19-0 | MDL MFCD04973795

Fmoc-Gabapentin is a Amino Acid reagent (Subcategory: Unusual AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.

Specifications
- CAS: 882847-19-0
- MDL: MFCD04973795
- InChIKey: JQJOWILVGOJWJF-UHFFFAOYSA-N
- Molecular Weight: 393.483
- Molecular Formula: C24H27NO4
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 2-(1-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclohexyl)acetic acid
- SMILES: O=C(CC1(CCCCC1)CNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)O

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Antibiotics

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Medchemexpress LLC HY-N0565B 5g , Doxycycline (hyclate) CAS:24390-14-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-P1975 5mg , Aureobasidin A CAS:127785-64-2 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10373 5mg , Trimetrexate CAS:52128-35-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-N0565B 5g , Doxycycline (hyclate) CAS:24390-14-5 Purity:>98%

Medchemexpress LLC HY-P1975 5mg , Aureobasidin A CAS:127785-64-2 Purity:>98%

Medchemexpress LLC HY-10373 5mg , Trimetrexate CAS:52128-35-5 Purity:>98%