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Filtered Search Results
Selleck Chemical LLC Clindamycin HCl S2457-1g
Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal used for the treatment of bacterial infections
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Selleck Chemical LLC Belnacasan (VX-765) S2228-200mg
Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0 8 nM in a cell-free assay Phase 2
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Selleck Chemical LLC Dinaciclib S2768-200mg
Dinaciclib is a novel and potent CDK inhibitor for CDK2 CDK5 CDK1 and CDK9 with IC50 of 1 nM 1 nM 3 nM and 4 nM in cell-free assays respectively It also blocks thymidine (dThd) DNA incorporation Dinaciclib induces apoptosis through the activation of caspases 8 and 9 Phase 3
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Biotium MemBrite™ Fix-ST 681/698 Cell Surface Staining Kit, 100 Reactions
MemBrite™ Fix Cell Surface Staining Kits are designed for covalently staining the surface of live cells to conveniently visualize cell boundaries in immunofluorescence experiments. MemBrite™ Fix are new covalent cell surface stains that react irreversibly with cell surface proteins for staining that can withstand formaldehyde or alcohol fixation, and detergent permeabilization. MemBrite™ Fix staining is rapid and non-toxic to cells, and because the dyes are highly water soluble, they stain cells much more evenly than traditional lipophilic membrane dyes like DiO, DiI, PKH, Vybrant, or CellMask™. MemBrite™ Fix-ST 681/698 is recommended for super-resolution imaging by STORM. This trial size kit has reagents sufficient for 100 labeling reactions. The kit contains 1 vial of MemBrite™ Fix-ST 681/698 that is sufficient for 20 uL of 1000X dye after DMSO reconstitution.
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Medchemexpress LLC Belnacasan | 273404-37-8 | MFCD11100350 | 10mg
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Belnacasan | Putity: 99.99% | MW: 509 | 273404-37-8 | MFCD11100350 | 10mg
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TENOVA PHARMACEUTICALS INC RAPAMYCIN-LC-FLUORESCEIN
NC3801553 RAPAMYCIN-LC-FLUORESCEIN
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eMolecules 53123-88-9 | Sirolimus | Advanced ChemBlocks - In Stock914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g...
Sirolimus | Advanced ChemBlocks - In Stock | 53123-88-9914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g | 381426230
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SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES CARBACHOL 1PC X 100MG
501847790 CARBACHOL 1PC X 100MG
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TARGETMOL CHEMICALS INC Tacrolimus 50mg
Tacrolimus can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase.
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AG Scientific Inc Blasticidin S HCl Sol, 5X1 ML
Blasticidin S HCL is an antibiotic that demonstrates a strong inhibitory effect on protein synthesis in eukaryotic and prokaryotic cells. Blasticidin causes tRNA to bond more strongly to the P site of the large ribosomal subunit while simultaneously deforming the tRNA, thus inhibiting proper translation. The ultimate result of this process is a significant suppression of the hydrolysis of peptidyl-tRNA along with inhibition of peptide bond formation. Isolated from Streptomyces griseochromogenes.CAS Number: 3513-03-9Molecular Weight: 458.9 DaChemical Formula: C17H26N8O5HClSolubility: Soluble in water. Clear and faint yellow solution at 5 mg/ml in water. Insoluble in organic solvents.Storage Temperature: +4CResearch or further manufacturing use only, not for food or drug use.
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AG Scientific Inc Hygromycin B in Water, 5X2 ML
The concentration of Hygromycin B in DI water is 100mg/ml. Hygromycin B is an aminoglycoside antibiotic effective against bacteria, fungi, and eukaryotic cells that are isolated from Streptomyces hygroscopicus. It is composed of amino groups attached to glycosides, that bind the 30s ribosomal subunits. This action causes the mRNA sequence to be misread, resulting in protein synthesis inhibition. Hygromycin B is also an antiviral agent, which works as a standard section antibiotic in gene experiments.CAS Number: 31282-04-09Molecular Weight: 527.5 DaChemical Formula: C20H37N3O13Storage Temperature: +4CResearch or further manufacturing use only, not for food or drug use.
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Apexbio Technology LLC Ionomycin free acid(Synonyms: Ionomycin (free acid), Antibiotic SQ 23377, SQ 23377, Calcium ionophore ionomycin), 5mg, CAS: 56092-81-0.
Ionomycin free acid (CAS 56092-81-0) is a selective calcium ionophore functioning by mediating Ca transport across biological membranes It forms complexes with calcium ions facilitating their passage through lipid bilayers and increasing intracellular Ca concentrations In vitro studies demonstrate its capacity to transfer calcium ions from aqueous to organic phases highlighting its ion carrier function In vivo experiments indicate ionomycin effectively activates mammalian oocytes promoting subsequent embryonic development Clinical research has employed ionomycin to assess improvements in fertilization outcomes for patients with decreased ovarian reserves
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Enzo Life Sciences Kanamycin . sulfate (5g). CAS: 25389-94-0
Aminoglycoside antibiotic with broad antibacterial spectrum, including mycobacteria, many Gram-positive and most Gram-negative bacteria. Inhibits bacterial protein synthesis. Kanamycin resistance is widely used as a selection marker for obtaining transgenic plants. Solubility: Soluble in water. Long Term Storage: +4°C.
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Medchemexpress LLC Polymyxin B1 | 4135-11-9 | MFCD01699017 | 98.90% | C56H98N16O13 | 1 MG
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Polymyxin B1 is a potent antimicrobial lipopeptide derived from Bacilus polymyxa. It is the major component in Polymyxin B and functions by inducing lysis of bacterial cells through interaction with their membranes. It holds potential for treating multidrug-resistant Gram-negative bacterial infections.
- Potent antimicrobial lipopeptide
- Derived from Bacilus polymyxa
- Major component in Polymyxin B
- Induces bacterial cell lysis by interacting with membranes
- Potential for treating multidrug-resistant gram-negative bacterial infections
- Binds to negatively charged sites in bacterial cell membranes
- Disrupts cell wall integrity and increases permeability for water and molecules
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Apexbio Technology LLC Quinacrine (hydrochloride hydrate),100mg
Quinacrine, also commonly known as atebrine, is a compound which is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels with an IC50 value of 3.3 μM and suppresses aldehyde oxidase with an IC50 value of 3.3 μM. Quinacrine prevents misfolding of prion protein with an EC50 value of 0.3 μM. As an effective riboflavin antagonist, quinacrine associates with the riboflavin-binding protein with a Ki value of 6.7 μM. Voltage-dependent sodium channels play a vital role in action potential initiation and propagation in excitable cells, including muscle, nerve, and neuroendocrine cell types. Other sizes are also available. Please inqury us for quote.
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