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Filtered Search Results
Apexbio Technology LLC Rapamycin (Sirolimus) 53123-88-9 10mM (in 1mL DMSO)
Rapamycin (Sirolimus) is an antifungal antibiotic originally isolated from the bacterium Streptomyces hygroscopicus It serves as an immunosuppressant agent widely employed in research to prevent graft rejection by inhibiting T-cell activation and proliferation Rapamycin exerts its biological function by binding intracellularly to FK-binding protein 12 (FKBP12) forming a rapamycin-FKBP12 complex that inhibits mTOR (mechanistic target of rapamycin) a serine-threonine kinase involved in cell cycle control cell growth and metabolism This compound is often used experimentally to study mTOR signaling pathways in cancer biology and immunological research frequently showing inhibitory activities with an IC50 range of approximately 0 1-20 nM in various cell-based assays
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Ubpbio Carbenicillin disodium salt, CAS# 4800-94-6, > 95% purity
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Carbenicillin is a semi-synthetic bactericidal antibiotic in the penicillin family. It primarily acts on Gram-negative bacteria. Carbenicillin is more stable than ampicillin and results in fewer satellite colonies on selection plates.
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eMolecules 83730-53-4 | l-Buthionine (S,R)-sulfoximine | Oakwood Chemical | MFCD00070309 | 222.300 | C8H18N2O3S | 97.000 | CCCCS(=N)(=O)CCC(N)C(O)=O | 100mg | 537664469
l-Buthionine (S,R)-sulfoximine | Oakwood Chemical | 83730-53-4 | MFCD00070309 | 222.300 | C8H18N2O3S | 97.000 | CCCCS(=N)(=O)CCC(N)C(O)=O | 100mg | 537664469
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Medchemexpress LLC Ampicillin trihydrate | 7177-48-2 | 99.9% | 100 G
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Ampicillin trihydrate is a broad-spectrum beta-lactam antibiotic effective against various gram-positive and gram-negative bacteria. For research use only.
- It inhibits the growth of E. coli of swine origin in a dose-dependent manner, with an effective inhibitory concentration of 2.5 uG/mL.
- It is effective in alleviating hemorrhagic enteritis symptoms in pigs.
- After oral administration, ampicillin trihydrate produces maximum concentrations in bile twice as high as in serum, and peak concentration in portal blood is twice as high as in peripheral blood.
- It also provides neuroprotection against ischemia-reperfusion brain injury by reducing MMPs activities and increasing GLT-1 expression, significantly reducing medial hippocampal cell death following global forebrain ischemia.
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Medchemexpress LLC Belnacasan | 273404-37-8 | MFCD11100350 | 10mg
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Belnacasan | Putity: 99.99% | MW: 509 | 273404-37-8 | MFCD11100350 | 10mg
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![eMolecules 53123-88-9 | Sirolimus | Advanced ChemBlocks - In Stock914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g...](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000162925.jpg-250.jpg)
eMolecules 53123-88-9 | Sirolimus | Advanced ChemBlocks - In Stock914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g...
Sirolimus | Advanced ChemBlocks - In Stock | 53123-88-9914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 1g | 381426230
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TENOVA PHARMACEUTICALS INC RAPAMYCIN-LC-FLUORESCEIN
NC3801553 RAPAMYCIN-LC-FLUORESCEIN
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Selleck Chemical LLC Marimastat
Marimastat (BB-2516 TA2516) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-9 MMP-1 MMP-2 MMP-14 and MMP-7 with IC50 of 3 nM 5 nM 6 nM 9 nM and 13 nM respectively Phase 3
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Medchemexpress LLC Polymyxin B1 | 4135-11-9 | MFCD01699017 | 98.90% | C56H98N16O13 | 1 MG
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Polymyxin B1 is a potent antimicrobial lipopeptide derived from Bacilus polymyxa. It is the major component in Polymyxin B and functions by inducing lysis of bacterial cells through interaction with their membranes. It holds potential for treating multidrug-resistant Gram-negative bacterial infections.
- Potent antimicrobial lipopeptide
- Derived from Bacilus polymyxa
- Major component in Polymyxin B
- Induces bacterial cell lysis by interacting with membranes
- Potential for treating multidrug-resistant gram-negative bacterial infections
- Binds to negatively charged sites in bacterial cell membranes
- Disrupts cell wall integrity and increases permeability for water and molecules
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Medchemexpress LLC HY-13861 100mg Medchemexpress, GW7647 CAS:265129-71-3 Purity:98%
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Medchemexpress,HY-13861 100mg GW7647 CAS:265129-71-3 Formula:C29H46N2O3S GW7647 is a potent PPARα agonist, with EC50s of 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ and PPARδ, respectively. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Pfanstiehl Inc Streptozotocin (S-141) 5g - API, active pharmaceutical ingredient CAS: 18883-66-4
Streptozotocin(S-141) 5g - API, active pharmaceutical ingredient CAS: 18883-66-4
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MEDCHEMEXPRESS LLC VIPIVOTIDE TETRAXETAN 5MG
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501872550 VIPIVOTIDE TETRAXETAN 5MG
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Medchemexpress LLC Ro4929097 10Nm 1Ml 98 Percent | HY-11102
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Ro4929097 10Nm 1Ml 98 Percent
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Medchemexpress LLC Vortioxetine hydrobromide | 960203-27-4 | C18H23BrN2S | 500 MG
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Vortioxetine hydrobromide is a multimodal serotonergic agent that acts as an antagonist for 5-HT3A and 5-HT7 receptors, an inhibitor of the 5-hydroxytryptamine transporter (SERT), a 5-HT1A agonist, and a partial 5-HT1B agonist. It is intended for research use.
- Antagonist for 5-HT3A and 5-HT7 receptors
- Inhibitor of 5-hydroxytryptamine transporter (SERT)
- Agonist for 5-HT1A receptors
- Partial agonist for 5-HT1B receptors
- Increases cell proliferation and survival
- Stimulates maturation of immature granule cells in hippocampus
- Does not cause cognitive or psychomotor impairment
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TARGETMOL CHEMICALS INC Tacrolimus 50mg
Tacrolimus can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase.
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