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Filtered Search Results
Medchemexpress LLC [4-[[5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl- | 1700693-08-8 | MFCD29472241 | 98.0% | 416.86 g/mol | C19H21ClN6O3 | 10 MG
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JH-II-127 is an orally active, highly potent, selective, and brain-permeable inhibitor of leucine-rich repeat kinase 2 (LRRK2) used in preclinical research to probe LRRK2 signaling and Parkinson's disease models. It shows low-nanomolar activity against wild-type and mutant LRRK2 and has characterized solubility and storage profiles for in vitro and in vivo studies.
- Highly potent LRRK2 inhibition (low-nanomolar IC50 values).
- Selective activity against wild-type and mutant LRRK2 variants.
- Brain permeable, suitable for central nervous system studies.
- High purity solid with defined storage conditions for stability.
- Documented solubility protocols for in vitro and in vivo use.
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Medchemexpress LLC Rad51-in-1 | 2101739-18-6 | 99.9% | 50 MG
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RAD51-IN-1 is a small-molecule inhibitor of the RAD51 recombinase, derived from B02, intended for preclinical cancer research to inhibit homologous recombination and reduce RAD51 foci formation in tumor cells.
- Inhibits RAD51-mediated homologous recombination.
- Displays cytotoxic activity in multiple human cancer cell lines with low micromolar IC50 values.
- Reported high purity (99.89%) and solid, yellow to orange physical form.
- Stable as a powder under recommended storage (powder: -20°C for years).
- Available in small solid quantities and as a 10 mM solution in DMSO for in vitro use.
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Medchemexpress LLC HY-100669 2mg Medchemexpress, Mycro 3 CAS:944547-46-0 Purity:>98%
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Medchemexpress, HY-100669 2mg Mycro 3 CAS:944547-46-0 Mycro 3 is a potent and selective c-Myc inhibitor in whole cell assays. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100833 5mg Medchemexpress, Antibiotic-5d CAS:251349-54-9 Purity:>98%
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Medchemexpress, HY-100833 5mg Antibiotic-5d CAS:251349-54-9 Antibiotic-5d is a synthesis and antimicrobial compound. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Warangalone (scandenolone) | 4449-55-2 | 404.46 | 1 MG
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Warangalone (scandenolone) | 4449-55-2 | 404.46 | 1 MG
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Apexbio Technology LLC Chloramphenicol(Synonyms: Chloromycetin, Levomycetin, Chlornitromycin, Fenicol, Amphicol, Kemicetine), 1g, CAS: 56-75-7.
Chloramphenicol (CAS 56-75-7) is a small molecule antibiotic commonly utilized in molecular biology research It exerts anti-microbial activity by specifically binding to the bacterial 50S ribosomal subunit thereby inhibiting the peptidyl transferase reaction and subsequently blocking protein synthesis At elevated concentrations chloramphenicol may also impede DNA synthesis in eukaryotic cells In plasmid selection assays typical effective concentrations are approximately 25 g/ml for stringent plasmids and 170 g/ml for relaxed plasmids For laboratory storage chloramphenicol solutions are maintained at 4 C
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TARGETMOL CHEMICALS INC GELDANAMYCIN 50MG
Also available in 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Geldanamycin an HSP90 inhibitor (Kd 1.2 uM) specifically disrupts glucocorticoid receptor (GR)/HSP association. purity: 98%
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Medchemexpress LLC HY-B0239 5g , Chloramphenicol CAS:56-75-7 Purity:98%
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Medchemexpress, HY-B0239 5g Chloramphenicol CAS:56-75-7 Formula:C11H12Cl2N2O5 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-111617 10mg Medchemexpress, BTR-1 CAS:18331-34-5 Purity:>98%
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Medchemexpress, HY-111617 10mg BTR-1 CAS:18331-34-5 BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Spiramycin S4082-50mg
Spiramycin (Formacidine) is a 16-membered ring macrolide (antibiotic)
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Apexbio Technology LLC ELTANEXOR KPT-8602 1MG
ELTANEXOR KPT-8602 1MG APEXBIO TECHNOLOGIES
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Medchemexpress LLC Cdk9-in-13 | 2768712-71-4 | 99.94% | 461.60 | 100 MG
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CDK9-IN-13 (compound 38) is a potent and selective CDK9 inhibitor, with an IC50 of <3 nM. It exhibits short half-lives in rodents. It is suitable for laboratory centrifugation and storage.
- Potent and selective cdk9 inhibitor
- Ic50 of <3 nm
- Short half-lives in rodents
- Cdk1: 0.14 μm
- Cdk2: 0.72 μm
- Cdk7: 0.40 μm
- Cdk12: 0.055 μm
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Medchemexpress LLC HY-10493 5mg Medchemexpress, Cobicistat CAS:1004316-88-4 Purity:>98%
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Medchemexpress, HY-10493 5mg Cobicistat CAS:1004316-88-4 Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) enzymes with IC50s of 30-285 nM. Cobicistat is a pharmacokinetic enhancer which increases the overall absorption of several HIV medications. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Biotin-PEG6-thalidomide | 2144775-48-2 | MFCD31561114 | 98.3% | C37H53N5O12S | 10MG
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Biotin-PEG6-thalidomide is a biotinylated polyethylene glycol (PEG6)-linked thalidomide derivative used as a PROTAC linker and cereblon (CRBN) affinity probe for targeted protein degradation research. It provides a hydrophilic spacer and a biotin handle to facilitate synthesis, biochemical assays, and affinity-based capture of protein complexes. Supplied for research use only.
- Provides a PEG6 spacer to increase solubility and flexibility
- Contains a thalidomide-derived moiety for cereblon binding
- Includes a biotin tag for affinity capture and pull-down assays
- Suitable for PROTAC synthesis and CRBN-binding studies
- Compatible with common organic solvents and assay conditions
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Selleck Chemical LLC Voriconazole 100mg 137234-62-9 UK-109496
Voriconazole (UK-109496) is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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